Pola sebaran tingkat infeksi bersama serotipe virus dengue di wilayah kajian RT-PCR Balai Besar Teknik Kesehatan Lingkungan dan Pengendalian Penyakit Yogyakarta: analisis data 2013-2015

https://doi.org/10.22146/bkm.11778

Fitria Wakano(1*), Lutfan Lazuardi(2), Eggi Arguni(3), Hari Kusnanto(4)

(1) Departemen Biostatistik, Epidemiologi dan Kesehatan Populasi Fakultas Kedokteran Universitas Gadjah Mada
(2) Departemen Kebijakan dan Manajemen Kesehatan Fakultas Kedokteran Universitas Gadjah Mada
(3) Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Gadjah Mada
(4) Departemen Biostatistik, Epidemiologi dan Kesehatan Populasi Fakultas Kedokteran Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Pattern of concurrent infection of dengue virus serotype in the regional study areas of Yogyakarta Center for Environmental Health and Diseases Control: an analysis of  2013-2015 data

Purpose

This study aimed to determine the pattern in the spread of infection rates with dengue viral serotypes.

Methods

The study was a descriptive research with spatial mapping methods. Data of 132 respondents were collected based on RT-PCR in 2013-2015. The complete address of the village-level patient from the dengue arbovirosis surveillance data of the Center for Environmental Health and Diseases Control Yogyakarta were used to determine the coordinate points with utilization of RBI and Google Earth maps in searching addresses for distribution of case coordinate points.

Results

There were similarities with the most complex quadruple joint infection rates of DEN in Semarang and Yogjakarta, while Kebumen obtained double DEN level. Three patterns of infection with DEN-1 and DEN-3 have p-value < 0.05 in Semarang in 2014, Sragen in 2015 and Semarang 2013 and 2 patterns in Gunung Kidul 2014 and Kulon Progo 2015. The patterns of infection with DEN-1, DEN-2 and DEN-3 in 2015 were covering Sragen and Semarang in 2013.

Conclusion

The most complex areas of infection were Semarang and Yogyakarta. The pattern of most likely cluster infection with DEN-1 and DEN-3 and DEN-1, DEN-2 and DEN-3 allegedly was a result of two infected patients, different serotypes of different mosquitoes or infection of more than one serotype of Ae. aegypti or Ae. albopictus as the main vector.


Keywords


region; level of joint infection; serotype; dengue virus



References

  1. WHO. Impact of Dengue. Available from: http:// www.who.int. Accessed 28 December 2015.
  2. Soegijanto. Demam Berdarah Dengue, Edisi dua, Airlangga University, Surabaya; 2006.
  3. Aryati, Wardhani, Yohan, Aksono dan Tedjo Sasmono. Distribusi Serotipe Dengue di Surabaya Tahun 2012. Indonesia Journal of Clinical Pathology and Medical Laboratory, Vol.19. 1, November 2012: 41-44. Diakses tanggal 4 Januari 2016
  4. Beti, Naiggolan, Putri, Rachmayanti, Albar, Indriastuti, Sjamsuridzal and Mirawati. Characterization of Dengue Virus Serotype 4 Infection in Jakarta, Indonesia, 2014;45(1) January 2014.
  5. Rafiq, Arif and Shaikh. Dengue In Pakistan: Journey From a Disease Free to a Hyper Endemic Nation Editorial. University of Health Sciences Karachi, 2011;5(3): 81-84.
  6. Wardani Diah WSR, Lutfan Lazuardi, Yodi Mahendradhata dan Hari Kusnanto. Pentingnya Analisis Cluster Berbasis Spasial dalam Penanggulangan Tuberkulosis di Indonesia. Jurnal Kesehatan Masyarakat Nasional 2013; 8(4).
  7. Rubens Jose Costalina, Maria Zélia Rouquayrol, Maria Roseli Monteiro, Maria Izabel Florindo and Claudia Pessoa. Interpretation Of The Presence Of Igm And Igg Antibodies In A Rapid Test For Dengue: Analysis Of Dengue Antibody Prevalence In Fortaleza City In The 20th Year Of The Epidemi, Revista da Sociedade Brasileira de Medicina Tropical 2012;45(2):163-167.
  8. Megariani, Rinang Mariko, Amrin Alkamar and Andani Eka Putra. Uji Diagnostik Pemeriksaan Antigen Nonstruktural 1 untuk Deteksi Dini Infeksi Virus Dengue pada Anak. Sari Pediatri, Vol. 16, No. 2, Agustus 2014, Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Andalas/RSUP dr. M. Djamil, Padang; 2014.
  9. Prasetyowati dan Nusa. DHF Cases Dominated by Den-3 Serotype In The West Java Province. Vol. 3, No. 1, June 2012, Vector Borne Disease Control, Research and Development Council, Ciamis, West Java; 2012.
  10. Jane P. Messina, Oliver J. Brady, Thomas W. Scott, Chenting Zou1, David M Pigott, Kristen A Duda, Samir Bhatt, Leah Katzelnick, Rosalina E Howes, Katerina E Battle1, Cameron P. Simmons and Simon I. Hay. Global spread of dengue virus types: mapping the 70 year history. Trends in Microbiology, March 2014, Vol. 22, No. 3
  11. Usavadee Thafara, Siriyasatien, Tawatsin, Asavadachanukorn, Surapee, Ratree and Mulla. Double infection of heteroserotypes of dengue Viruses in field populations of aedes aegypti and Aedes albopictus (diptera: culicidae) and Serological features of dengue viruses found in patients in southern Thailand. Dengue Viruses In Field Populations Of Dhf Vectors 2006;37(3) May 2006. National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi 11000, Thailand.
  12. Carvalho Araujo, Rita Maria Ribeiro Nogueira, Joselio Maria Galvao de Araujo, Izabel Leicia Cavalcante Ramalho, Maria Lucia Feitosa de Sa Roriz, Maria Elizabeth Lisboa de Melo and Ivo Castelo Branco Coelho. Concurrent Infection With Dengue Virus Type-2 and DENV-3 In a Patient From Ceara, Brazil, Laboratorio Central de Saúde Pública do Ceara, Fortaleza, CE, Brasil Laboratório de Flavivirus, Instituto Oswaldo Cruz-Fiocruz, Mem Inst Oswaldo Cruz, Rio de Janeiro, 2006 Vol. 101(8): 925-928
  13. Pino M A Loron, C.B Cropp, J.A Farfa, A.V Vorndam, E.M Rodri Guez-Angulo, E.P Rosado-Paredes, L.F Flores-Flores, B.J Beaty and D.J Gubler. Common Occurrence Of Conccurent Infections By Multyple Dengue Virus Serotypes; 1999.
  14. Gubler. Dengue and Dengue Hemorrhagic Fever, Clinical Microbiology Reviews, July 1998, p. 480–496 Vol. 11, No. 3. Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services; 1998.
  15. Aldstadt Jared, In-Kyu Yoon, Darunee Tannitisupawong, Richard G. Jarman, Stephen J. Thomas, Robert V. Gibbons, Angkana Uppapong, Sopon Iamsirithaworn, Alan L. Rothman, Thomas W. Scott and Timothy Endy. Space-time Analysis of Hospitalised Dengue Patients in Rural Thailand Reveals Important Temporal Intervals in the Pattern of Dengue Virus Transmission. Jurnal Tropical Medicine and International Health 2012;17(9) pp 1076–1085.
  16. Jakkrawarn Chompoosri, Usavadee Thavara, Apiwat Tawatsin, Surapee nantapreecha dan Padet Siriyasatien. Seasonal Monitoring of Dengue Infection in Aedes aegypti and Serological Feature of Patients with Suspected Dengue in 4 Central Provinces of Thailand. National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok; 2012.
  17. Bharaj Preeti, Chahar, Pandey, Diddi, Lalit, Guleria, Kabra and Broor. Concurrent infections by all four dengue virus serotypes during an outbreak of dengue in 2006 in Delhi, India. Virology Journal 2008;5(1). From: www.virologyj.com. Diakses tanggal 28 Desember 2015.
  18. Jehangir Khan, Asar Khan. Incidence of dengue in 2013: Dengue Outbreak In District Swat, Khyber Pakhtunkhwa, Pakistan. International Journal of Fauna and Biological Studies 2013;2(1): 01-07.
  19. Dissanayake V H W , N D Gunawardena, N C A Gunasekara, D R S Siriwardhana and N Senarath. Shift in The Transmission Pattern Of Dengue Serotypes And Concurrent Infection With More Than One Dengue Virus Serotype. Ceylon Medical Journal 2011;56: 176-178.
  20. Zhang Chunlin, Mammen P. Mammen, Jr, Piyawan Chinnawirotpisan, Chonticha Klungthong, Prinyada Rodpradit, Patama Monkongdee, Suchitra Nimmannitya, Siripen Kalayanarooj, and Edward C. Holmes. Clade Replacements in Dengue Virus Serotypes 1 and 3 Are Associated with Changing Serotype Prevalence. Journal Of Virology, 2005;79(24) p. 15123–15130.
  21. Wilder Smith Annelies, Sutee Yoksan, Arul Earnest, Ravathi Subrahmaniam and Nicholas I Paton. Serological Evidence For The Co-circulation Of Multiple Dengue Virus Serotypes in Singapore. Epidemiol. Infect. 2005;133, 667–671.
  22. Anop M., Aneesh Issac, Thomas Matheuw, Sairu Philip, Nabeel Abdul Kareem, R Unnikrishnan and E Sreekumar. Genetic Charaterization of Dengue Virus Serotype Caunsing Concurrent Infection In an Outbreak In Ernakulam, Kerala, South India. Indian Journal Of Experimental Biology 2010;48, pp.849-857



DOI: https://doi.org/10.22146/bkm.11778

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