STUDI PENGGUNAAN OBAT ANTI TUBERKULOSIS PADA PASIEN TB-HIV/AIDS DI RSUP SANGLAH DENPASAR TAHUN 2009

Abstract

Background and Objective: A retrospective descriptive study
of anti-tuberculosis drugs in patients with TB - HIV/AIDS who
were hospitalized Nusa Indah Sanglah Hospital 2009 aims to
determine suitability of the use of anti-tuberculosis (OAT) to
the National Treatment Guidelines 2008 which consists of types
of drugs, combination drug and dosage, also to identify drug
interactions that do occur based on the level of significance.
Results and Conclusions: The results showed that the use
of OAT category 1 has the largest percentage of 61.7% and
then use of a combination of streptomycin with ethambutol
which is 12%, then use of isoniasid and rifampin which has a
percentage of 6%. The percentage of the correct dose 60.9%,
8.7% is not appropriate, and not identified was 30.4%. Usage
of the appropriate OAT that is equal to 74% and 26% did not
deserve. Drug interactions occurred in 23 patients with a
significant percentage of drugs that interact with a percentage
of 11.1%, the importance of 2 namely 33.3%, the importance
of 3 namely 0%, significance 4 namely 16.7%, and the
significance was 5 of 55, 6%.
Keywords: tuberculosis, TB-HIV/AIDS, suitability