Nyeri kepala tumor otak pada dewasa
https://doi.org/10.22146/bns.v18i2.54989 Kusumo Dananjoyo(1), Whisnu Nalendra Tama(2*), Rusdy Ghazali Malueka(3), Ahmad Asmedi(4)
(1) Departemen Neurologi Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada, Yogyakarta
(2) Departemen Neurologi Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada, Yogyakarta
(3) Departemen Neurologi Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada, Yogyakarta
(4) Departemen Neurologi Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada, Yogyakarta
(*) Corresponding Author
Abstract
Sebagian besar pasien datang ke pelayanan kesehatan dengan keluhan nyeri kepala intensitas ringan hingga sedangkan, sedangkan pasien dengan keluhan nyeri kepala hebat datang ke Unit Gawat Darurat. Sebagian besar pasien takut penyebab nyeri kepala adalah tumor otak. Prevalensi nyeri kepala pada tumor otak bervariasi, sekitar 32,2% hingga 71%. Nyeri kepala pada tumor otak bersifat tidak spesifik, dapat menyerupai nyeri kepala primer namun memiliki perjalanan klinis tumor otak. Prevalensi tumor otak asimptomatik pada suatu meta analisis yang melibatkan 16 penelitian neuroimaging dengan 19.559 pasien menunjukkan angka yang rendah, sekitar 0,7%. Abnormalitas pada MRI otak menunjukkan 14,1% nyeri kepala pada tumor otak menyerupai nyeri kepala tegang (1,4%) dan migraine (0,6%).
Pada artikel ini, kami bertujuan menjelaskan karakteristik nyeri kepala pada tumor otak pada pasien dewasa dan memberikan rekomendasi kapan dilakukan pemeriksaan neuroimaging, dan mendiskusikan patofisiologi dan terapi nyeri kepala terkait tumor otak.
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1.Rasmussen BK, Jensen R, Schroll M. Epidemiology of headache in a general population–a prevalence study. J Clin Epidemiol. 1991;44(11):1147–1157.
2.Dousset V, Henry P, Michel P. Epidemiology of headache. Rev Neurol (Paris). 2000;156(Suppl 4):4S24–29.
3.Kurth T, Buring JE, Rist PM. Headache, migraine and risk of brain tumors in women: prospective cohort study. J Headache Pain. 2015;16:501.
4.Hamilton W, Kernick D. Clinical features of primary brain tumours: A case-control study using electronic primary care records. Br J Gen Pract. 2007;57(542):695–699.
5.Morris Z, Whiteley WN, Longstreth WT Jr, Weber F, Lee YC, Tsushima Y, et al. Incidental findings on brain magnetic resonance imaging: systematic reviewand meta-analysis. BMJ. 2009;339:b3016.
6.Wang HZ, Simonson TM, Greco WR, Yuh WT. Brain MR imaging in the evaluation of chronic headache in patients without other neurologic symptoms. Acad Radiol. 2001;8(5):405–408.
7.Frishberg BM, Rosenberg JH, Matchar DB, McCrory DC, Pietrzak MP, Rozen TD. Evidence-based guidelines in the primary care setting: neuroimaging in patients with nonacute headache. American Academy of Neurology. 2000; 25 p. Available from: tools.aan.com/ professionals/practice/pdfs/gl0088.pdf.
8.Taylor LP. Mechanism of brain tumor headache. Headache. 2014;54(4):772–775.
9.Goffaux P, Fortin D. Brain tumor headaches: from bedside tobench. Neurosurgery. 2010;67(2): 459–466.
10.Vazquez-Barquero A, Ibanez FJ, Herrera S, Izquierdo JM, Berciano J, Pascual J. Isolated headache as the presenting clinical manifestation of intracranial tumors: a prospective study. Cephalalgia. 1994;14(4):270–272.
11.Antunes NL. The spectrum of neurologic disease in children with systemic cancer. Pediatr Neurol. 2001;25(3):227–235.
12.Hadidchi S, Surento W, Lerner A, Liu CS, Gibbs WN, Kim PE, et al. Headache and Brain Tumor. Neuroimag Clin N Am. 2019;29(2);291-300.
13.Society TIH. The International Classification of Headache Disorders. 3rd ed. 2018. Available from: https://www.ichd-3.org/
14.Forsyth PA, Posner JB. Headaches in patients with brain tumors:a study of 111 patients. Neurology. 1993;43(9):1678–1683.
15.Pfund Z, Szapary L, Jaszberenyi O, Nagy F. Headache in intracranial tumors. Cephalalgia. 1999;19(9):787–790.
16.Sarah N, Lynne PT. Headaches in Brain Tumor Patients: Primary or Secondary? Headache. 2014:776-785.
17.Schankin CJ, Ferrari U, Reinisch VM, Birnbaum T, Goldbrunner R, Straube A. Characteristics of brain tumour-associated headache. Cephalalgia. 2007;27(8):904–911.
18.Russo M,Villani V, Taga A, Genovese A, Terrenato I, Manzoni GC, et al. Headache as a presenting symptom of glioma: A cross-sectional study. Cephalalgia. 2018 Apr;38(4):730-735.
19.Valentinis L, Tuniz F, Valent F, Mucchiut M, Little D, Skrap M, et al. Headache attributed to intracranial tumours: A prospective cohort study. Cephalalgia. 2010;30(4):389–398.
20.Christiaans MH, Kelder JC, Arnoldus EP, Tijssen CC. Prediction of intracranial metastases in cancer patients with headache. Cancer. 2002;94(7):2063–2068.
21.Guillem A, Barriga FJ, Gimenez-Roldan S. Nummular headache associated to arachnoid cysts. J Headache Pain. 2009;10(3):215–217.
22.Edvardsson B, Persson S. Cluster headache and arachnoid cyst. Springerplus. 2013;2(1):4.
23.Kang SY, Choi JC, Kang JH, Lee JS. Huge supratentorial arachnoid cyst presenting as an orgasmic headache. Neurol Sci. 2012;33(3):639–641.
24.Douglas AC, Wippold FJ 2nd, Broderick DF, Aiken AH, Amin-Hanjani S, Brown DC, et al. ACR appropriateness criteria headache. J Am Coll Radiol. 2014;11(7):657–667.
25.Levy MJ. The association of pituitary tumors and headache. Curr Neurol Neurosci Rep. 2011;11(2):164–170.
26.Kahn K, Finkel A. It is a tumor–current review of headache and brain tumor. Curr Pain Headache Rep. 2014;18(6):421.
27.Ansari SF, Terry C, Cohen-Gadol AA. Surgery for vestibular schwannomas: A systematic review of complications by approach. Neurosurg Focus. 2012;33(3):E14.
28.Kirby S, Purdy RA. Headaches and brain tumors. Neurol Clin. 2014;32(2):423–432.
29.Brandsma D, Stalpers L, Taal W, et al. Clinical features, mechanisms, and management of pseudo-progression in malignant gliomas. Lancet Oncol. 2008;9(5):453–61.
30.Lou E, Turner S, Sumrall A, Reardon DA, Desjardins A, Peters KB, et al. Bevacizumab-induced reversible posterior leukoencephalopathy syndrome and successful retreatment in a patient with glioblastoma. J Clin Oncol. 2011; 29(28):e739–742.
31.Steinmann D, Paelecke-Habermann Y, Geinitz H, Aschoff R, Bayert A, Bolling T, et al. Prospective evaluation of quality of life effects in patients undergoing palliative radiotherapy for brain metastases. BMC Cancer. 2012;12:283.
DOI: https://doi.org/10.22146/bns.v18i2.54989
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