Fabrikasi Sensor Elektrokimia Berbasis Karbon dan Nanopartikel Perak (NPAg) Untuk Mendeteksi Acetaminophen

https://doi.org/10.22146/ijeis.54115

Nurafni Julianti(1*), Roberth Victoria Manurung(2), Arifin Arifin(3)

(1) Departemen Fisika, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Hasanuddin
(2) Pusat Penelitian Elektronika dan Instrumentasi, Lembaga Ilmu Pengetahuan Indonesia
(3) Departemen Fisika, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Hasanuddin
(*) Corresponding Author

Abstract


Acetaminophen (paracetamol) is one of the most heavily used analgesic drugs especially for pain or pain relief. The excess of acetaminophen for the human body produces a bad effects, one of them is a liver disease. In this study, silver nanoparticle (NPAg) is synthesized using Turkevich methods to increase the conductivity or the rate of transfer electron in the carbon’s surface. So, the sensitivity from electrochemical sensors to acetaminophen can be enhanced. The stability test was done by three samples from Ag/AgCl reference electrodes, each of them is 10 – 30 mV, 0,94 – 35 mV, and 20 – 67 mV. Generally, the performing of Ag/AgCl refrence elecrodes can be concluded as fairly stable with voltage less than 100 mV. From the data acetaminophen sample test, the peak of oxidation happens on 0,2 – 0,4 mV session, and the current produced increased significantly. The results of characterization using SEM morphology in NPAg have a smaller pores because of the size of the partical is also big. While the characterization using FTIR produces four kinds of functional groups including C-O, C-H, NO2, and N-H functional groups.

Keywords


Silver nanoparticles; Acetaminophen; Carbon

Full Text:

PDF


References

[1] I. Seikhshoaie, F. Garkani dan H. Beitollahi. An Electrochemical Acetaminophen Sensor Based on La3+/Co3O4 Nanoflowers Modified Graphite Screen Printed Electrode Architeccture. Original Article, vol. 10, no. 2, pp. 154-162, 2019.

[2] D. Apriandanu, S. Wahyuni, S. Hadisaputro dan Harjono. “Sintesis Nanopartikel Perak Menggunakan Metode Poliol Dengan Agen Stabilisator Polivinilalkohol (PVA)”. Jurnal MIPA, vol. 36, no, 2, pp.157-168, 2013.

[3] A. Mazzonello, V. V. Valdramidis, C. Farrugia, J. N. Grima dan R. Gatt. “Synthesis ‘and Characterization of Silver Nanoparticles”. International Journal of Modern Engineering Reseacrh (IJMER), vol. 7, no. 3, pp. 41-49, 2017.

[4] S. Ahmad, M. Ahmad, B. L. Swami dan S. Ikram. “A Review on Plants Extract Mediated Synthesis of Silver Nanoparticles for Antimocrobial Applications: A Green Expertise”. Journal of Advanced Research, no. 7, pp. 17-28, 2016.

[5] S. L. A. Paluri, M. L. Edwards, N. H. Lam, E. M. Williams, A. Meyerhoefer dan I. E. P. Sizemore . “Introduction “Green” and “Nongreen” Aspects of Noble Metal Nanoparticles Synthesis: An Inquiry-Based Laboratory Experiment for Chemistry and Engineering Students”. Journal Chemical Education, no. 92, pp.350-354, 2015.

[6] S. Yesilot dan C. Aydin. “Silver Nanoparticles; A New Hope In Cancer Therapy?”. Eastern Journal of Medicane, vol. 24, no. 1, pp. 111-116, 2019.

[7] I. Ristian, S. Wahyuni dan K. I. Supardi. “Kajian Pengaruh Konsentrasi Perak Nitrat Terhadap Ukuran Partikel Pada Sintesis Nanopartikel Perak”. Indonesian Journal of Chemical Science, vol. 3, no. 1, pp. 7-11, 2014.

[8] M. Akter, et. al. “A Systematic Review on Silver Nanoparticles-Induced Cytoxity: Physicochemical Properties and Perspectives”. Journal of Advanced Research, no. 9, pp. 1-16, 2018.

[9] M. Khairy, B. C. Mahmoud dan C. E. Banks. “Simultaneous Determination of Codeineanditsco-Formulated Drugs Acetaminophen and Caffeine by Utilising Cerium Oxide Nanoparticles Modified Screen Printed Electrodes”. Sensors and Actuators B: Chemical, no. 259, pp. 142-254, 2018.

[10] N. K. Isvani, A. Mulyasuryani dan S. Prasetyawan. “Jurnal Kimia Valensi: Jurnal Penelitian dan Pengembangan Ilmu Kimia”.Kinerja Biosensor Konduktometri Berbasis (Screen Printed Carbon Electrode) SPCE-Kitosan Untuk Deteksi Diazinon, Malatinon, Klorpirifos dan Profenofos, vol. 1, no. 2, pp. 83-90, 2015.

[11] I. Seikhshoaie, F. Garkani dan H. Beitollahi. “Original Article”. An Electrochemical Acetaminophen Sensor Based on La3+/Co3O4 Nanoflowers Modified Graphite Screen Printed Electrode Architeccture, vol. 10, no. 2. pp. 154-162, 2019.

[12] A. Debataraja, Hiskia dan R. V. Manurung. “Fabrikasi Biotranduser Dengan Metode Amperometrik Studi Awal Sensor Unsur Hara Tanah”. Prosiding Conference on Smart-Green Technology in Electrical and Information Systems, pp. 121-124, 2013.

[13] K. Khaira. “Analisis Kadar Tembaga (Cu) dan Zeng (Zn) dalam Air Minum Isi Ulang Kemasan Galon di Kecamatan Lima Kaum Kabupaten Tanah Datar”. Jurnal Saintek, vol. VI, no. 2. pp. 116-123, 2014

[14] A. Mulyasuryani, R. T. Tjahhanto dan R. Andawiyah. Simultaneous Voltammetric Detection of Acetaminophen and Caffeine Base on Cassava Starch-Fe3O4 Nanoparticles Modified Glassy Carbon Electrodes. Journal Chemosensors, vol. 7, no. 49, pp. 1-11, 2019.

[15] J. C. Miller, dan J. N. Miller, 1991, Statistic and Chemmometrics for Anatycal Chemistry, Six Edition. Ashford Colour Press. UK.

[16] T. Rahman, M. A. Fadhlulloh, A. B. D. Nandiyanto dan A. Mudzakir. Review: Sintesis Karbon Nanopartikel. Integr. Proses, vol. 5, pp. 120-131, 2015.

[17] E. Y. Lembang, dan M. M. Zakir. Sintesis Nanopartikel Perak dengan Metode Reduksi Menggunakan Bioreduktor Ekstrak Daun Ketapang, pp. 1-11, 2016.

[18] P. Harry, dan S. T. Limbong. Identifikasi Gugus Fungsi Senyawa Kimia Pulp Batang Pisang Berdasarkan Spektrum FTIR. Jurnal Teknik dan Teknologi, vol. 12, no. 23, 2017.



DOI: https://doi.org/10.22146/ijeis.54115

Article Metrics

Abstract views : 2147 | views : 5225

Refbacks

  • There are currently no refbacks.




Copyright (c) 2020 IJEIS (Indonesian Journal of Electronics and Instrumentation Systems)

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.



Copyright of :
IJEIS (Indonesian Journal of Electronics and Instrumentations Systems)
ISSN 2088-3714 (print); ISSN 2460-7681 (online)
is a scientific journal the results of Electronics
and Instrumentations Systems
A publication of IndoCEISS.
Gedung S1 Ruang 416 FMIPA UGM, Sekip Utara, Yogyakarta 55281
Fax: +62274 555133
email:ijeis.mipa@ugm.ac.id | http://jurnal.ugm.ac.id/ijeis



View My Stats1
View My Stats2