The Comparison of some General Anesthetics Preparation in Cat Orchiectomy Based on the Onset and Duration of Anesthesia

Abstract

Castration surgery (orchiectomy) is the most common operation performed by veterinarians to control the feral cat population. This study aims to determine the relative potency of the most effective anesthetic from the many types of anesthetic preparations available in terms of the onset and duration of anesthesia. The right anesthetic selection can help the smoothness of controlling the cat population in the environment with minimum side effects, which will improve their welfare and lower the possibility of zoonotic diseases. In this study, the comparison of the relative potency of anesthetic Ket-A-Xyl®, ketamine, ketamine-acepromazine combination, and ketamine-acepromazine-atropine combination in domestic cats (Felis domestica) was tested. Each group consists of 9 cats with 3 comparison groups data from another study. The groups namely A1 (ketamine) as control, A2 (ketamine-acepromazine), A3 (ketamine-acepromazine-atropine), and group A4 (Ket-A-Xyl®) which from the experiment. Acepromazine and atropine as premedication were administered subcutaneously, while Ket-A-Xyl® and ketamine were administered intramuscularly. All data were tested with statistical methods ANOVA and Kruskal-Wallis. The results showed that the onset of anesthesia in group A4 had a significant difference (P<0.05) compared to groups A1 and A3. While the duration of anesthesia, groups A2, A3, and A4 were significantly different compared to groups A1 (P<0.05), however, there was no significant difference between groups A2, A3, and A4. It can be concluded that the Ket-A-Xyl® preparation is the most effective anesthetic among the four test groups in terms of onset but there is no significant difference in terms of duration.