Identification of single nucleotide polymorphism of gen insuline-like growth factor binding protein 2 on growth of native chicken

Abstract

Insulin-like growth factor binding protein 2 (IGFBP 2) regulates a broad spectrum of biological activities involved in growth, development, and differentiation. Single nucleotide polymorphisms (SNP) of IGFBP 2 was selected to identify the genotype of black and white colors feather of native chicken with restriction fragment length polymorphism. Trait data from total 48 black and white colors feathers chicken from random population was recorded. The association of the SNP with the weekly body weight was analyzed. The results of the factor analysis indicated that the genotypes of the SNP were only significantly associated with body weight at DOC, and at 7, 14, and 21 day of age. The frequency of restriction enzyme C/T alleles in the black color was 0.48 (C) and 0, 52 (T), for the white color 0.41 (C) and 0.59 (T), and for black and white 0.45 (C) and 0.55 (T). Genotype among black, white, and black-white colors feather did not differ from the expected Hardy-Weinberg equilibrium.