Changes in Anthropometry Measurement among Human Immunodefi ciency Virus/Acquired Immune Defi ciency Syndrome (HIV/AIDS) Patients Received Antiretroviral Treatment
Adi Irawan(1*), Doni Priambodo Wijisaksono(2), Rizka Humardewayanti(3), Yanri WIjayanti(4)
(1) 
(2) 
(3) 
(4) 
(*) Corresponding Author
Abstract
Background: Estimated nearly 38.6 million people infected by HIV and 2.8 million died in 2005. Evidence suggests the existence of a very important relationship between the output and improved nutritional status
in HIV/AIDS patients. Poor nutritional status in HIV/AIDS can be caused by several factors, namely the intake and absorption of inadequate nutrition, metabolic changes, hyper metabolism, or a combination of these, changes in the gastrointestinal tract as well as interactions between drugs and nutrients. Losing weight remains on the HAART (Highly Active Antiretroviral Therapies) era, but the problems are the side effects of HAART and lipodystrophy.
Objective: The purpose of this study is to determine the provision of anti- retroviral effect on changes in anthropometric values people with HIV/AIDS. Method: The study is using the one group pre-posttest design (quasi-experimental), by assessing changes in anthropometric values in subjects with HIV before and after the administration of ARVs. Analysis of the data is computerized by a computer program Result: Obtained 30 samples of the study with anthropometric changes pre and post ARVs 6 months. The
weight was 51.4 ± 9.12 to 53.6 ± 8.68 with a p-value 0.001. Body Mass Index (BMI) was 19.98 ± 3.47 into 20.84 ± 3.35 with a p-value 0.001 and upper arm circumference 24.13 ± 3.62 into 24.95±3.48 with a p-value 0.003. The provision of antiretroviral drugs for 6 months infl uences the change in nutritional status of HIV patients are assessed by anthropometric measure. Signifi cant changes in the changes body weight, BMI
and upper arm circumference. Changes in anthropometric values ARV Efavirenz group and non-Efavirenz meaningful change signifi cant in skinfold thickness obtained at the value of p 0.010.
Conclusion: There were no signifi cant changes in anthropometric values compared to patients with early stage HIV and advanced stage after 6 months of antiretroviral therapy.
Keywords: HIV, antiretroviral drugs, anthropometric, nutritional status
Full Text:
PDFReferences
Suttajit, M. Advances in Nutrition Support for Quality of Life in HIV/AIDS. Asia Pac J Clin Nutr. 2007. 16: 318-22.
Stambullian, M., Felin, S and Slobodianik, N.H. Nutritional status in patients with infection and AIDS. British Journal of Nutrition. 2007. 8; 1: 140-3.
HIV/AIDS Bureau. Health Care and HIV: Nutritional Guide for Providers and Clients. 2002. 2: 1-6.
FANTA. Nutrition and HIV/AIDS: A Training Manual for Nurses and Midwives. 2003. 3: 79-94.
Chow, D. C., Day, L. J., Souza, S and Shikuma, C. M. Metabolic complication of HIV therapy. 2006. HIV insite. May.
Ma d i y o n o, B. , Mo e s l i k h a n , S. , Sastroasmoro, S.,Budiman I., Purwanto, S.H., Perkiraan Besar Sampel, In: Sastroasmoro, S., Ismael, S., (Ed): Dasar- Dasar Metodologi Penelitian Klinis, Eds 3. Sagung Seto, Jakarta: 2010. 302-331.
Grinspoon, S., Carr A. Cardiovascular Risk and Body-Fat Abnormalities in HIV-Infected Adults. N Engl J Med 2005;2005.352:48-62.
Mangili, A., Murman, D. H., Zampini, A. M., Wanke, C. A. Nutrition in HIV Infection: Review of weight loss and wasting in the era of Highly Active Antiretroviral Therapy From the Nutrition for healthy living cohort. Clinical Infectious Disease. 2006. 43: 836-42.
Robl e s D. T. , Ol son J. M. HIV Lipodystrophy. 2008.
DOI: https://doi.org/10.22146/acta%20interna.16851
Article Metrics
Abstract views : 1207 | views : 897Refbacks
- There are currently no refbacks.
Copyright (c) 2014 Acta Interna The Journal of Internal Medicine
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Acta Interna The Journal of Internal Medicine Indexed by:
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.