Type of Psychosocial Stressor as Risk Factor of Depressive Symptom in Metabolic Syndrome

https://doi.org/10.22146/actainterna.27002

Ana Fauziati(1*), Agus Siswanto(2), Luthfan Budi Purnomo(3)

(1) 
(2) 
(3) 
(*) Corresponding Author

Abstract


Background: Metabolic syndrome and depression are two major diseases over the world, which are increasing in prevalence over time. Depression is major mental health burden over the world. In long time, depression can lead to metabolic syndrome, while metabolic syndrome is risk factor for developing depression. Chronic stress that induced by psychosocial
stressor lead to the development of both metabolic syndrome and depression. Further research is important to identify which type of psychosocial stressor is the risk factor for depression symptom in patient with metabolic syndrome.
Aims: This study is to identify the type of psychosocial stressor which could be the risk factor for depressive symptom.
Method: The study design was case control. The case group consisted of metabolic syndrome patients with depressive symptom, while the control group consisted of metabolic syndrome patients without depressive symptom. Metabolic syndrome was diagnosed based on International Diabetes Federation (IDF) criteria. Depressive symptom was measured by Beck Depression Inventory (BDI). Psychosocial stressors were measured by Stressful Life Events (SLE) questionnaire. Dependent variable was depressive symptom, while independent variables were type of psychosocial stressors (finance, work, social relationship, health and housing). Analysis methods that used in this study were independent t test, Pearson/Spearman correlation analysis, chi square and logistic regression.
Result: There were 54 patients in this study, consisted of 24 in case group and 30 incontrol group. There was no significant difference in most basic characteristics between two groups. There was significant difference of SLE score between two groups. Chi square analysis showed that housing, finance, health, social relationship, and work stressors were risk factors for
developing depressive symptom in metabolic syndrome (OR 24.5; 9.7; 8.4; 5.4; 3.9 respectively, significant). Demographic factor which also influenced depressive symptoms was salary less than 1 million per month (OR 45, significant). According to logistic regression analysis, psychosocial stressors which most influenced the depressive symptom were finance and housing.
Conclusion: The study showed that housing, finance, health, social relationship and work stressors were risk factors for developing depressive symptomp in metabolic syndrome.


Keywords


Psychosocial stressor, metabolic syndrome, depression

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References

Eckel, R.H., 2008. The metabolic syndrome. Chapter 236:1509-1513, in: Fauci, A.S., Braunwald, E., Kasper, D.L., Hauser, S.L., Longo, D.L., Jameson, J.L., Loscalzo, J. (Eds.). Harrison’s Principles of Internal Medicine, 17th ed., McGraw Hill Medical, New

York.

Reus, V.I., 2008. Mental disorders. Chapter 386:2710-2723, in: Fauci, A.S., Braunwald, E., Kasper, D.L., Hauser, S.L., Longo, D.L., Jameson, J.L., Loscalzo, J. (eds.), 2008. Harrison’s Principles of Internal Medicine, 17th ed., McGraw Hill Medical, New York.

Zuberi, S.I., Syed, E.U., Bhatti, J.A., 2011. Association of depression with treatment outcomes in type 2 diabetes mellitus: a cross sectional study from Karachi, Pakistan. BMC Psychiatry, 11(27):1-6.

Pouwer, F. & Snoek, F.J., 2001. Association between symptoms of depression and the glycaemic control may be unstable across gender. Diabetic Medicine, 18:595-598.

Zihl, J., Schaaf, L., Ziler, E.A., 2010. The relationship between adult neurophysiological profiles and diabetic patient’s glycemic control. Applied Neurophysiology, 17:44-51

Eren, I., Erdi, O., Sahin, M., 2008. The effect of depression on quality of life of patients with type II diabetes mellitus Depression and Anxiety, 25; 98-106.

Hyvarinen, M.P., Wahlbeck, K., Erickson, J.G., 2007. Quality of life and metabolic status in mildly depressed patients with type 2 diabetes treated with paroxetine: a double-blind randomized controlled 6-month trial. BMC Family Practice, 8(34):1-7.

Vanhala, M, Jokelainen, J., Kiukaanniemi, K., S., Kumpuasalo, E.,Koponen, H.,2009. Depressive symptomspredispose females to metabolic syndrome: a 7 year follow up study. Acta Psychiatrica Scandinavica, 119:137- 142.

Dortland, R.A.K.B., Giltay, E.J., Veen, T., Zitman, F.G., Penninx, B.W.J.H., 2010. Metabolic syndrome abnormalities are associated with severity of anxiety and depression and with tricyclic antidepressant use. Acta Psychiatrica Scandinavica, 122:30-39.

Akbaraly, T.N., Ancelin, M.L., Jaussent, I., Ritchie, C., Gateau, P.B., et al., 2011. Metabolic syndrome and onset of depressive symptoms in the elderly findings from the three city study. Diabetes Care, 34:904-909.

Toker, S., Shirom, A., Melamed, S., 2008. Depression and the metabolic syndrome: gender dependent associations. Depression and Anxiety, 25:661-669.

Heiskanen T., Viinamaki, H., Lehto, S.M., Niskanen, L., Honkanen, K., et al., 2009. Association of depressive symptoms and the metabolic syndrome in men. Acta Psychiatrica Scandinavica, 120:23-29.

Akbaraly, T.N., Kivimaki, M., Brunner, E.J., Chandola, T., Marmot, M.G., et al., 2009. Association between metabolic syndrome and depressive symptoms in middle-aged adults results from the Whitehall II study. Diabetes Care, 32(3):499-504.

Hartley, T.A., Knox, S.S., Fekedulegn, D., Leiker, C.B., Violanti, J.M., et al., 2012. Association between depressive symptoms and metabolic syndrome in police officers: results from two cross sectional studies. Journal of Environmental and Public Health, 1-9.

Meittola, J., Niskanen, L.K., Vinamaki, H., Kumpusalo, E., 2008. Metabolic syndrome is associated with self perceived depression. Scandinavian Journal of Primary Helath Care, 26:203-210.

Demirci, H., Cinar, Y., Bilgel, N., 2011. Metabolic syndrome and depressive symptoms in a primary health care setting in Turkey. Bulletin of Clinical Psychopharmacology, 21(1):49-57.

Hildrum, B., Mykletun, A., Midthjell, K., Ismail, K., Dahl, A.A., 2009. No association of depression and anxietywith the metabolic syndrome: the Norwegian HUNT study. Acta Psychiatrica Scandinavica, 120:14-22.

Foley, D.L., Morley, K.I., Madden, P.A.F., Heath, A.C., Whitfield, J.B., Martin, N.G., 2010. Major depression and the metabolic syndrome. Twin Research and Human Genetics, 13(4):347-358.

Mudjaddid, E. & Shatri, H., 2009. Gangguan psikosomatik: gambaran umum dan patofisiologinya, in: Sudoyo, A.W., Setiyohadi, B., Alwi, I., Simadibrata, M.K., Setisti, S. (editor). Buku Ajar Ilmu Penyakit Dalam. jilid III, edisi V., page: 2093-2097. Interna Publishing, Jakarta.

Pyykkonen, A.J., Raikkonen, K., Tuomi, T., Erickson, J.G., Groop, L., Isomaa, B., 2010. Stressful life events and the metabolic syndrome. Diabetes Care, 33(2): 378-384.

Bjontorp, P., 2001. Do stress reaction cause abdominal obesity and comorbidities?. Obesity Reviews, 2:73-86.

Vogelzangs, N., 2010. Depression & Metabolic Syndrome. Dissertation. Universiteit Amsterdam.

Sharpley, C.F., 2009. Neurobiological pathway between chronic stress and depression: dysregulated adaptive mechanisms?. Clinical Medicine: Psychiatry 2:39-45.

Dahlan, M.S., 2010. Besar Sampel dan Cara Pengambilan Sampel dalam Penelitian Kedokteran dan Kesehatan, ed. 3:46-60. Salemba Medika Publisher, Jakarta.

Toker, S., Shirom, A., Melamed, S., 2008. Depression and the metabolic syndrome: gender dependent associations. Depression and Anxiety, 25:661-669.

Lloyd, C.E., Dyert, P.H. dan Barnett, A.H., 2000. Prevalence of symptoms of depression and anxiety in a diabetes clinic population. Diabetic Medicine, 17:198-202.

Dunbar, J.A., Reddy, P., Lameloise, N.D., Philpot, B., Laatikanen, T., Kilkkinen, A., et al., 2008, Depression: an important comorbidity with metabolic syndrome in a general population, Diabetes Care 31: 2368-2373.

Kinder, L.S., Carnethon, M.R., Palaniappan, L.P., King, A.C., Fortmann, S.P., 2004. Depression and the metabolic syndrome in young adults: findings from the Third National Health and Nutrition Examination Survey. Psychosom Med 66:316 –322.

Gatineau, M. & Dent, M. 2011. Obesity and Mental Health. Oxford: National Obesity Observatory, pp:1-28.

Herva, A., Rasanen, P., Miettunen, J., Timonen, M., Laksy, K., Veijola, J., Laitinen, J., Ruokonen, A., Joukamaa, M, 2004. Co occurrence of metabolic syndrome with depression and anxiety in young adults: the Northern Finland 1966 Birth Cohort Study. Psychosom Med 68:213–216.



DOI: https://doi.org/10.22146/actainterna.27002

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