Maxillary Reconstruction Timing in Severe Systemic Lupus Erythematous (SLE) Patient with Bone Destruction due to Invasive Aspergillosis: Case Report

https://doi.org/10.22146/actainterna.62845

Yulyani Werdhiningsih(1*), Ayu Paramaiswari(2), Deddy Nur Wachid Achadiono(3), Nyoman Kertia(4)

(1) Subspecialty Training Program of Internal Medicine, Division of Rheumatology, Department of Internal Medicine Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/ Dr. Sardjito General Hospital
(2) Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/ Dr. Sardjito General Hospital
(3) Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/ Dr. Sardjito General Hospital
(4) Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/ Dr. Sardjito General Hospital
(*) Corresponding Author

Abstract


Severe Systemic Lupus Erythematosus patient was in the third of 28-days-cycle cyclophosphamide chemotherapy when the early symptoms of aspergillus infection occurred. This developed into extensive cranial bone damage. It was planned to get a biopsy and debridement for bone and soft tissue to diagnose and therapy palate osteonecrosis, followed by reconstruction surgery. This case report aimed to report the successful management of a severe patient on chemotherapy undergoing several operations so that the SLE aspergillosis is optimally managed.


Keywords


SLE; Invasive Aspergillosis; immunocompromised

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References

Sumariyono ,Handono K, Setyohadi B, Hidayat R, Najirman, Hamijoyo L., et al . Rekomendasi Perhimpunan Reumatologi Indonesia untuk Diagnosis dan Pengelolaan Lupus Eritematosus Sistemik. Perhimpunan Reumatologi Indonesia, 2019. 2. Ginzier EM, Dvorkina O. Infection in systemic lupus erythematosus. In: Hahn BH, Wallace DJ, editors. Dubois’ lupus erythematosus. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2007. p. 902–7. 3. Hung ML, Liao HT, Chen WS, Lai CC, Tsai CY, Chang DM. Invasive aspergillosis in patients with systemic lupus erythematosus: a retrospective study on clinical characteristics and risk factors for mortality.Lupus (2018) 0, 1–9. 4. Hahn BH., McMhon MA., Wilkinson A., Wallace WD., Daikh DI., Fitzgerald JD., et al. American College of Rheumatology Guidelines for Screening, Treatment, and Management of Lupus Nephritis.Arthritis Care & Research Vol. 64, No. 6, June 2012, pp 797– 808 DOI 10.1002/acr.21664 5. Fanouriakis A., Kostopoulou M., Alunno A., Aringer M., Bajema I., Boletis JN., et al. 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus. Ann Rheum Dis 2019;0:1–10. doi:10.1136/annrheumdis-2019-215089. 6. Pubchem-NIH. LiverTox,https://www.ncbi.nlm.nih.gov/books/n/livertox/Cyclophosphamide/.NCITheosaurus(NCIt).https://pubchem.ncbi.nlm.nih.gov/source/NCI%20Thesaurus%20(NCIt). 7. Eid RA., Razavi GSE., Mkrtichyan M.,Janik J., Khleif SN. Old-School Chemotherapy in Immunotherapeutic Combination in Cancer, A Low-cost Drug Repurposed.www.aacrjournals.org.2016 8. National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.1992. 9. Ben-Menachem E.Systemic Lupus Erythematosus: A Review for Anesthesiologists.www.anesthesia-analgesia.org.September 2010 • Volume 111 • Number 3. 10. Lacerda MA. Chemotherapy and Anesthesia. Rev Bras Anestesiol 2001; 51: 3: 250 - 270. 11. Kyung Yoo T, Gon Moon H, Han W, Young Noh D. 2017. Time interval of neoadjuvant chemotherapy to surgery in breast cancer: how long is acceptable? Gland Surg 2017;6(1):1-3.http://dx.doi.org/10.21037/gs.2016.08.06 12. Ministério da Saúde (BR) Secretaria de Atenção à Saúde. Departamento de Regulação, Avaliação e Controle Manual de bases técnicas da oncologia - SIA/SUS - sistema de informações ambulatoriais.Disponível email: http://portal.saude.gov.br/portal/arquivos/pdf/manual3_drac.pdf]. 2010.



DOI: https://doi.org/10.22146/actainterna.62845

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