Efek ekstrak teh hijau (Camellia sinensis (L.) O. Kuntze var. assamica) terhadap berat badan dan kadar malondialdehid wanita overweight

Alpha Olivia Hidayati; Wiryatun Lestariana; Emy Huriyati

doi:10.22146/ijcn.15377

Efek ekstrak teh hijau (Camellia sinensis (L.) O. Kuntze var. assamica) terhadap berat badan dan kadar malondialdehid wanita overweight

https://doi.org/10.22146/ijcn.15377

Alpha Olivia Hidayati^(1*), Wiryatun Lestariana⁽²⁾, Emy Huriyati⁽³⁾

(1) Politeknik Muhammadiyah Yogyakarta
(2) Bagian Biokimia, Fakultas Kedokteran Universitas Gadjah Mada
(3) Program Studi Gizi Kesehatan, Fakultas Kedokteran Universitas Gadjah Mada
(*) Corresponding Author

Abstract

Background: Overweight and obesity were risk factors of various degenerative diseases. Green tea extract contains polyphenol compounds, particularly catechins which act as antioxidants, fat dissolvent and aid lipolysis. Thus, it is necessary to study the use of green tea as an alternative treatment to overcome overweight.

Objective: To identify the effect of green tea extract supplementation on body weight and malondialdehide (MDA) level of overweight women in Yogyakarta District Health Office.

Method: This was an experimental study with double-blind randomized controlled trial design. Subject of the study were divided into two groups; one group consumed green tea extract capsules and the other consumed placebo. Weight, 6 times 24 hours recall, and level of MDA were measured on every subject.

Results: The results revealed that green tea extract has a weight-reducing effect and decrease MDA level of overweight women, though the reduction of weight and MDA level was not significant (p>0,05). Weight loss of 1.3% was observed in the treatment group, whereas the control group has an increase of 0.6% body weight, but the weight change was not significant (p=0.501, p=0.620). Changes in body weight after 12 weeks of treatment showed a significant disparity between the two groups (p=0.000). MDA level decreased by 10% in the treatment group compared to 8.3% in the control group. MDA levels pre and post intervention was significantly different in the treatment group (p=0.006), whereas in the control group there was no significant discrepancy observed (p=0.123). However, changes in MDA levels after 12 weeks of treatment showed no significant differences among groups (p=0.278). The mean nutrient intakes of subjects were still below the recommended dietary allowance (RDA), except for protein.

Conclusion: Green tea extract had a weight-reducing effect and decrease MDA level of overweight women in Yogyakarta District Health Office, though the reduction was not statistically significant.

Keywords

green tea extract; overweight; body weight; malondialdehid

Full Text:

PDF

References

Misnadiarly. Obesitas sebagai faktor risiko beberapa penyakit. Jakarta: Pustaka Obor Populer; 2007.

Badan Penelitian Pengembangan Kesehatan. Laporan hasil riset kesehatan dasar (Riskesdas) Indonesia – tahun 2010. Jakarta: Departemen Kesehatan Republik Indonesia; 2011.

Adiningsih S. Indonesia nutritional pattern in contributing prevalence of obesity. Fight obesity from cells to community. Malang: Laboratorium Ilmu Faal FK UNIBRAW; 2006.

Cabrera C, Artacho R, Gimenez R. Benefical effect of green tea. J Am Coll Nutr 2006;25(2):79–99.

Dewi K. Pengaruh ekstrak teh hijau (Camellia sinensis var. Assamica) terhadap penurunan berat badan, kadar trigliserida dan kolesterol total pada tikus jantan Galur Wistar. JKM 2008;7(2):156–63.

Toruon PL, Lukman G, Bony O. Performance nutrition. Jakarta: Prima Diet Catering; 2008.

Chu DC, Juneja LR. General chemical composition of green tea and its infusion. Chemistry and applications of green tea. New York: CRC Press New York; 1997.

Gunawiyaya FA. Penentuan LD-50 ekstrak teh hijau pada mencit strain C3H. Majalah Ilmu Kedokteran USAKTI 1996;15(4):1645–50.

Yang CS, Landau JM. Effect of tea consumption on nutrition and health. J Nutr 2000;130(10):2409–12.

Westerterp-Plantega MS, Lejeune MP, Kovacs EM. Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation. Obes Res 2005;13(7):1195–204.

Naim R. Manfaat teh hijau bagi kesehatan. Jurnal Medika 2003;4:243–5.

Nagao T, Komine Y, Soga S, Meguro S, Hase T, Tanaka Y, Tokimitsu I. Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Am J Clin Nutr 2005;81(1):122–9.

Onge MP. Dietary fats, teas, dairy, and nuts: potensial functional foods for weight control. Am J Clin Nutr 2005;81(1):7–15.

Hartoyo A, Mary A. Aktivitas antioksidatif dan hipokolesterolemik ekstrak teh hijau dan teh wangi pada tikus yang diberi ransum kaya asam lemak tidak jenuh ganda. Jurnal Teknologi dan Industri Pangan 2002;8(1):78–85.

Lemeshow S, Hosmer Jr DW, Klar J, Lwanga SK. Adequacy of sample size in health studies. Toronto: Willey & Sons; 1990.

WHO. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004;363(9412):157–63.

Winarsi H. Antioksidan alami dan radikal bebas: potensi dan aplikasinya dalam kesehatan. Yogyakarta: Kanisius; 2007.

Gibney MJ, Margetts GM, Kearney JM, Arab L. Gizi kesehatan masyarakat. Jakarta: EGC; 2008.

Chis B. Ensiklopedia keperawatan (churchilllivingstones mini encyclopaedia of nursing 1st ed). Jakarta: EGC; 2005.

Shils ME, Moshe S, Catharine R, Benjamin, Robert JC. Modern nutrition in health and disease. 10 ed. London: Lippincott Williams & Wilkins; 2006.

Murray RK, Granner DK, Mayes PA, Rodwell VW. Biokimia harper (Harper’s Illustrated Biochemistry). 27 ed. Jakarta: Penerbit buku kedokteran EGC; 2006.

Hardani E. Efek pemberian ekstrak teh hijau (Camelia sinensis (L.)O Kuntze) var. assamica terhadap total lemak tubuh dan profil lipid wanita dewasa overweight di lingkungan pegawai Dinas Kesehatan Kota Yogyakarta [Tesis]. Yogyakarta: Universitas Gadjah Mada; 2011.

Diepvens K, Westerterp KR, Westerterp-Plantega MS. Obesity and thermogenesis related to the consumtion of caffein, ephedrine, capsaicin, and green tea. Am J Physiol Regul Integr Comp Physiol 2007;292(1):R77–85.

Dullo AG, Durret C, Rohrer D, Giardier L, Mensi N, Fathi M, Chantre P, Vandermander J. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr 1999;70(6):1040–5.

Venables MC, Hulston CJ, Cox HR, Jeukendrup AE. Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans. Am J Clin Nutr 2008;87(3):778–84.

Koketsu M. Antioxidative activity of tea polyphenols. In: Takehiko Y, Lekh RJ, Djoing CC, Mujo K. Chemistry and applications of green tea. New York: CRC Press New York; 1997.

Zhu QY, Huang Y, Chen ZY. Interaction between flavonoids and alpha-tocopherol in human low density lipoprotein. J Nutr Biochem 2000;11(1):14–21.

Soliman GZA. Blood lipid peroxidation (superoxide dismutase, malondialdehyde, glutathion) level in egyption type 2 diabetic patients. Singapore Med J 2008;49(2):129–36.

Metzler DE. Biochemistry the chemical reactions of living cells. New York: Academic Press.Inc; 1977.

DOI: https://doi.org/10.22146/ijcn.15377