Stomatitis aftosa yang diperparah oleh iritasi kimiawi obat tradisional

Ayu Fresno Argadianti; Yuliana Yuliana; Hening Tuti Hendarti; Desiana Radithia

doi:10.22146/mkgk.53046

Stomatitis aftosa yang diperparah oleh iritasi kimiawi obat tradisional

https://doi.org/10.22146/mkgk.53046

Ayu Fresno Argadianti^(1*), Yuliana Yuliana⁽²⁾, Hening Tuti Hendarti⁽³⁾, Desiana Radithia⁽⁴⁾

(1) Program Studi Ilmu Penyakit Mulut Program Pendidikan Dokter Gigi Spesialis, Fakultas Kedokteran Gigi, Universitas Airlangga, Surabaya, Jawa Timur Departemen Ilmu Penyakit Mulut, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta
(2) Departemen Ilmu Penyakit Mulut, Fakultas Kedokteran Gigi, Universitas Airlangga, Surabaya, Jawa Timur
(3) Departemen Ilmu Penyakit Mulut, Fakultas Kedokteran Gigi, Universitas Airlangga, Surabaya, Jawa Timur
(4) Departemen Ilmu Penyakit Mulut, Fakultas Kedokteran Gigi, Universitas Airlangga, Surabaya, Jawa Timur
(*) Corresponding Author

Abstract

Stomatitis aftosa adalah suatu kondisi inflamasi dengan etiologi yang belum diketahui, ditandai dengan ulserasi sangat nyeri di mukosa rongga mulut selama 7 hingga 14 hari. Berbagai faktor berpengaruh dalam pembentukannya, salah satunya adalah trauma lokal. Perawatan diberikan untuk meredakan nyeri, mengeliminasi sumber trauma, dan penyembuhan ulserasi. Tujuan laporan kasus ini adalah untuk melaporkan stomatitis aftosa yang diperparah oleh iritasi kimiawi obat tradisional. Seorang laki-laki berusia 64 tahun mengeluh sariawan pada gusi kiri bawah terasa nyeri sejak kurang lebih 1 minggu yang lalu. Pasien mengoleskan suatu obat cair tradisional untuk meredakan rasa nyeri tapi kemudian rasa nyeri timbul kembali dan belum mereda. Tanda vital normal kecuali skor VAS (visual analog scale) nyeri mulut 6/10. Pemeriksaan ekstra oral normal, pemeriksaan intra oral didapatkan ulkus soliter berukuran 1x1,5 cm pada lipatan bukal regio 34, 35 dengan peninggian tanpa indurasi dan nyeri. Tata laksana meliputi anamnesis untuk mengetahui faktor yang memperparah, pemeriksaan klinis, debridement lesi untuk menghilangkan jaringan nekrotik dan aplikasi obat topikal gel mengandung klorin dioksida. Pasien diinstruksikan untuk berhenti mengoleskan obat tradisionalnya dan menggunakan obat yang diresepkan. Lesi sembuh dalam waktu 13 hari. Stomatitis aftosa dapat diperparah oleh iritasi kimiawi. Anamnesis, pemeriksaan klinis, debridement lesi dan pemberian obat yang tepat dapat membantu tata laksana dan penyembuhan yang efektif.

Keywords

gel; kimia; klorin dioksida; stomatitis aftosa; trauma

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References

1. Khan NF, Ghafoor F, Khan AA. Pathogenesis of recurrent aphthous stomatitis: a review of literature. Proceeding S.Z.P.G.M.I. 2006; 20(2): 113-118.

2. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral & Maxillofacial Pathology, 2nd Edition, Philadelphia: W.B. Saunders Company; 2002.

3. Ghom AG. Textbook of Oral Medicine, 2nd Edition. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2010.

4. Noszticzius Z, Wittmann M, Kaly-Kullai K, Beregvari Z, Kiss I, Rosivall L, Szegedi J. Demonstating that chlorine dioxide is a size-selective antimicrobial agent and high purity clo2 can be used as a local antiseptic. 2013; http://arxiv.org/ftp/arxiv/papers/1304/1304.5163.pdf. Diakses: 5 Februari 2018.

5. Fourie J, Boy SC. Oral mucosal ulceration – a clinician’s guide to diagnosis and treatment. SADJ. 2016; 71(10): 500-508.

6. Anura A. Traumatic oral mucosal lesions: a mini review and clinical update. OHDM. 2014; 13(2): 254-259.

7. The Soap and Detergent Association. Glycerine: An Overview. 1990; www.aciscience.org/docs/glycerine_-_an_overview.pdf. Diakses: 18 Maret 2018.

8. European Medicines Agency. Questions and Answers on Ethanol in the Context of the Revision of the Guideline on ‘Excipients in the Label and Package Leaflet of Medicinal Products for Human Use’, Science Medicines Health; 2014.

9. Shah SA, Maxood A, Shah SI. Incidence of endodontic flare-ups using either calcium hydroxide or creosote as intracanal medicament in symptomatic teeth. JKCD. 2010; 1(1): 15-19.

10. Zimmer M. On the Early Use of Creosote in Dentistry. Australian Endodontic Journal. 2002; 26(3): 124-128.

11. Clayton GD, Clayton FE. Patty’s Industrial Hygiene and Toxicology Volume 2A, 2B, 2C: Toxicology, 3rd ed. New York: John Wiley Sons; 1981. 2603.

12. Bhuiyan MNI, Begum J, Nandi NC, Akter F. Constituents of the Essential Oil from Leaves and Buds of Clove (Syzigium caryophyllatum (L.) Alston). African Journal of Plant Science. 2010; 4(11): 451-454.

13. Aishwarya J, Harini N, Karthikeyan M. Clove oil and its role in oral health – a review. International Journal of Pharmaceutical Science and Health Care. 2014; 4(3): 155-168.

14. Mohoammadi NS, Ozgunes H, Basaran N. Pharmacological and toxicological properties of eugenol. Turk J Pharm Sci. 2017; 14(2): 201-206.

15. Hosseini M, Asl MK, Rakhshandeh H. Analgesic effect of clove essential oil in mice. Avicenna Journal of Phytomedicine. 2011; 1(1): 1-6.

16. Sarrami N, Pemberton MN, Thornhill MH, Theaker ED. Adverse reactions associated with the use of eugenol in dentistry. British Dental Journal. 2002; 193(5): 257-259.

17. Nisha AD, Nautiyal U. A Review: oral gels for mouth ulcer. International Journal of Recent Advances in Pharmaceutical Research. 2016; 6(3): 1-11.

18. Vowden K, Vowden P. Debridement Made Easy, Wounds UK; 2011. 7(4): 1-4.

19. Fernandez R, Griffiths R. Water for wound cleansing. Cochrane Database of Systematic Reviews. 2012; (2): 1-30.

20. Wolcott R, Fletcher J. The role of wound cleansing in the management of wounds. Wounds International. 2014; 1(1): 25-31.

21. Yeturu SK, Acharya S, Urala AS, Pentapati KC. Effect of aloe vera, chlorine dioxide, and chlorhexidine mouth rinses on plaque and gingivitis: a randomized controlled trial. Journal of Oral Biology and Craniofacial Research. 2016; 6: 54-58.

22. Shinada K, Ueno M, Konishi C, Takehara S, Yokoyama S, Zaitsu T, Ohnuki M, Wright FAC, Kawaguchi Y. Effect of a mouthwash with chlorine dioxide on oral malodor and salivary bacteria: a randomized placebo-controlled 7-day trial. Trials. 2010; 11(14): 1-11.

23. Young RO. Chlorine dioxide (CLO2) as a non-toxic antimicrobial agent for virus, bacteria and yeast (Candida albicans). Int J Vaccines Vaccin. 2016; 2(6): 00052.

24. Mo Z, Hu S, Hu D. Kinetics of the preparation of chlorine dioxide by sodium chlorite and hydrochloric acid at low concentration. Chemical Engineering Transactions. 2015; 46: 49-54.

25. Al-Bayaty F, Abdulla MA. A Comparison of wound healing rate following treatment with aftamed and chlorine dioxide gels in streptozotocin-induced diabetic rats. Evidence-Based Complementary and Alternative Medicine; 2012. 1-8.

26. Young AR, Jonski G, Rolla G. The Oral anti-volatile sulphur compound effects of zinc salts and their stability constants. Eur J Oral Sci. 2002; 110: 31-34.

27. George JP, Shobha R, Lazarus FJ. Folic acid: a positive influence on periodontal tissues during health and disease. Int J Health Allied Sci. 2013; 2: 145-152.

28. Subramaniam T, Subramaniam A, Chowdhery A, Das S, Gill M. Versatility of aloe vera in dentistry – a review. IOSR-Journal of Dental and Medical Sciences. 2014; 13(10): 98-102.

29. Cavalcante GM, de Paula RJS, de Souza LP, Sousa FB, Mota MRL, Alves APNN. Experimental model of traumatic ulcer in the cheek mucosa of rats. Acta Cirurgica Brasileira. 2011; 26(3): 227-234.

DOI: https://doi.org/10.22146/mkgk.53046