The The COmprehensive Registry and rEsearch on Heart Failure (CORE-HF) : 2 years report from single-center Indonesian heart failure clinic registry 2-years Report from CORE-HF Database
Main Article Content
Abstract
Introduction: Heart failure (HF) remains a rising global epidemic which lacking population-based data, especially in Indonesia. The COmprehensive Registry and rEsearch on Heart Failure (CORE-HF) is a single-center registry of Sebelas Maret HF Clinic as part of the ongoing national HF registry under InaHF. This paper designed to give an overview of HF epidemiological data, thus improves HF service quality, especially at Surakarta region.
Methods: The CORE-HF is a cohort, prospective, single-center registry which enrolls all patients with chronic HF. Subjects were recruited consecutively from the outpatient clinic of Sebelas Maret HF Clinic at UNS Academic Hospital. Both enrollment and follow-up have been performed since January 2018 until present. Variables recorded consist of basic characteristics, baseline risk factors, subjective indicators, objective diagnostic assessments, pharmacological therapy, and outcome indicators.
Results: HFrEF has a significant association towards a higher number of rehospitalization and all-cause mortality at any time (p<0.001). The 12 and 24-months cardiac related rehospitalization occurred significantly more in HFrEF group compared to other groups (p<0.001), whereas rehospitalization in HFpEF dominated by non-cardiac cause (p=0.381). Cumulative all cause mortality is significantly highest in HFrEF group for any period of time (p<0.001).
Conclusion: As a part of InaHF National HF registry, the CORE-HF registry focuses in chronic HF and designed to give an overview of HF epidemiological data, especially at Surakarta region. Together with HF Clinic system, we assure not only the optimal GDMT for all indicative patients, but also patient’s compliance.
Article Details
References
Shah KS, Xu H, Matsouaka RA, Bhatt DL, Heidenreich PA, Hernandez AF, Devore AD, Yancy CW and Fonarow GC. Heart Failure With Preserved, Borderline, and Reduced Ejection Fraction: 5-Year Outcomes. J Am Coll Cardiol. 2017;70:2476-2486.
Orso F, Fabbri G and Maggioni AP. Epidemiology of Heart Failure. Handb Exp Pharmacol. 2017;243:15-33.
Rajadurai J, Tse HF, Wang CH, Yang NI, Zhou J and Sim D. Understanding the Epidemiology of Heart Failure to Improve Management Practices: An Asia-Pacific Perspective. J Card Fail. 2017;23:327-339.
Su A, Al'Aref SJ, Beecy AN, Min JK and Karas MG. Clinical and Socioeconomic Predictors of Heart Failure Readmissions: A Review of Contemporary Literature. Mayo Clin Proc. 2019;94:1304-1320.
Reyes EB, Ha JW, Firdaus I, Ghazi AM, Phrommintikul A, Sim D, Vu QN, Siu CW, Yin WH and Cowie MR. Heart failure across Asia: Same healthcare burden but differences in organization of care. Int J Cardiol. 2016;223:163-167.
Groenewegen A, Rutten FH, Mosterd A and Hoes AW. Epidemiology of heart failure. Eur J Heart Fail. 2020;22:1342-1356.
Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, Falk V, Gonzalez-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GMC, Ruilope LM, Ruschitzka F, Rutten FH and van der Meer P. 2016 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure. Rev Esp Cardiol (Engl Ed). 2016;69:1167.
Siswanto B, Hersunarti N, Erwinanto, Barack R, Pratikto R, Nauli S and Lubis A. PEDOMAN TATALAKSANA GAGAL JANTUNG. PERHIMPUNAN DOKTER SPESIALIS KARDIOVASKULAR INDONESIA. 2015:48.
Mahmood SS, Levy D, Vasan RS and Wang TJ. The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective. Lancet. 2014;383:999-1008.
Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W and Voigt JU. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28:1-39 e14.
Mitchell C, Rahko PS, Blauwet LA, Canaday B, Finstuen JA, Foster MC, Horton K, Ogunyankin KO, Palma RA and Velazquez EJ. Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults: Recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr. 2019;32:1-64.
Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE, Jr., Colvin MM, Drazner MH, Filippatos GS, Fonarow GC, Givertz MM, Hollenberg SM, Lindenfeld J, Masoudi FA, McBride PE, Peterson PN, Stevenson LW and Westlake C. 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. 2017;136:e137-e161.
Vergaro G, Ghionzoli N, Innocenti L, Taddei C, Giannoni A, Valleggi A, Borrelli C, Senni M, Passino C and Emdin M. Noncardiac Versus Cardiac Mortality in Heart Failure With Preserved, Midrange, and Reduced Ejection Fraction. J Am Heart Assoc. 2019;8:e013441.
Heo S, Shin MS, Hwang SY, An M, Park JK, Kim S, Shim JL and Kim J. Sex Differences in Heart Failure Symptoms and Factors Associated With Heart Failure Symptoms. J Cardiovasc Nurs. 2019;34:306-312.
Turana Y, Tengkawan J and Soenarta AA. Asian management of hypertension: Current status, home blood pressure, and specific concerns in Indonesia. J Clin Hypertens (Greenwich). 2020;22:483-485.
Lloyd-Jones DM, Larson MG, Leip EP, Beiser A, D'Agostino RB, Kannel WB, Murabito JM, Vasan RS, Benjamin EJ, Levy D and Framingham Heart S. Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation. 2002;106:3068-72.
Holipah H, Sulistomo HW and Maharani A. Tobacco smoking and risk of all-cause mortality in Indonesia. PLoS One. 2020;15:e0242558.
Crespo-Leiro MG, Anker SD, Maggioni AP, Coats AJ, Filippatos G, Ruschitzka F, Ferrari R, Piepoli MF, Delgado Jimenez JF, Metra M, Fonseca C, Hradec J, Amir O, Logeart D, Dahlstrom U, Merkely B, Drozdz J, Goncalvesova E, Hassanein M, Chioncel O, Lainscak M, Seferovic PM, Tousoulis D, Kavoliuniene A, Fruhwald F, Fazlibegovic E, Temizhan A, Gatzov P, Erglis A, Laroche C, Mebazaa A and Heart Failure Association of the European Society of C. European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions. Eur J Heart Fail. 2016;18:613-25.
Smaha LA and American Heart A. The American Heart Association Get With The Guidelines program. Am Heart J. 2004;148:S46-8.
Israili ZH and Hall WD. Cough and angioneurotic edema associated with angiotensin-converting enzyme inhibitor therapy. A review of the literature and pathophysiology. Ann Intern Med. 1992;117:234-42.
Borghi C and Veronesi M. Cough and ACE Inhibitors: The Truth Beyond Placebo. Clin Pharmacol Ther. 2019;105:550-552.