EFFECT OF STORAGE LENGTH ON PHYSICAL AND CHEMICAL STABILITY OF HAIR GROWTH LOTION CONTAINING CANDLENUT EXTRACT (Aleurites moluccana L. Willd.)

https://doi.org/10.22146/tradmedj.7998

Anas Putro Senu Prasojo(1), Sri Mulyani(2), Mufrod Mufrod(3*)

(1) Faculty of Pharmacy, Universitas Gadjah Mada
(2) Faculty of Pharmacy, Universitas Gadjah Mada
(3) Faculty of Pharmacy, Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Etanolic extract 70% of candlenut which has 5% concentration have been reported to have hair restoring activity. This study aims to investigate the effect of length storage on physical stability and flavonoid content of hair restoring lotion candlenut extract so that produce an acceptable form. Lotion were made in variation of xanthan gum concentration 0.5%; 1%; 1.5%. Flavonoid content were measured by densitometry. Observation result of physical stability such as latched power, viscosity test, and flavonoid content were statistically analyzed. Result of formula orientation showed that lotion which has 1% concentration of xanthan gum was the best which has latched power less than 1 second, viscosity increased weekly, and segregation was not occur. Type of emulsion result was o/w. Densitometry result showed that there were decrease of relative flavonoid ontent before and after storage, but it was not significant (α = 0.58).

Keywords


Lotion, candlenut (Aleurites moluccana L. Willd.), stability, hair growth



References

Anonim, 1995, Farmakope Indonesia, Edisi IV, 6-7, 554, 687, 713, 988, Departemen Kesehatan Republik Indonesia, Jakarta

Ansel, H.C., 1989, Pengantar Bentuk Sediaan Farmasi, diterjemahkan oleh Farida Ibrahim, Edisi IV, 377-390, UI-Press, Jakarta

Handayani, R., dan Sulistyo, J., 2008, Sintesis Senyawa Flavonoid-α-Glikosida secara Reaksi Transglikosida Enzimatik dan Aktivitasnya sebagai Antioksidan, Biodiversitas, 9, 1-4

Markham, K.R., 1982, Cara Mengidentifikasi Flavonoid, diterjemahkan oleh Kosasih Padmawinata, 1-21, Penerbit ITB, Bandung

Nielloud, F. dan Marti-Mestres, G., 2000, Pharmaceutical Emulsions and Suspensions, 7-9, 433-434, Marcel Dekker Inc., New York

Martin A., Swarbick, J., Cammarata, A., 1993, Farmasi Fisik : Dasar-Dasar Farmasi Fisik dalam Ilmu Farmasetik, diterjemahkan oleh Yoshita, Edisi III , 1143-1175, Penerbit Universitas Indonesia, Jakarta

Said, H., 2009, Panduan Merawat Rambut, 75, 89-92, Penebar Plus, Jakarta

Singh, K.K., 2006, Xanthan Gum, dalam Rowe, R.C., Shesky, P.J., Owen, S.C. (Eds.), Handbook of Pharmaceutical Excipients, 5th Edition, 821-823, Pharmaceutical Press, Chicago

Ulfah, A.M., 2003, Aktivitas Ekstrak Etanolik Biji Kemiri (Aleurites moluccana L. Wild) sebagai Pemicu Pertumbuhan Rambut Kelinci Putih Jantan serta Uji Kualitatif Kandungan Kimianya, Skripsi, Fakultas Farmasi UGM, Yogyakarta



DOI: https://doi.org/10.22146/tradmedj.7998

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 ISSN 2406-9086
Faculty of Pharmacy
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