ANTIANEMIA ACTIVITY OF Parkia speciosa Hassk SEED ETHANOLIC EXTRACT

https://doi.org/10.22146/tradmedj.8140

Shella Nursucihta(1), Hanifah Ataina Thai’in(2), Denade Mawlidya Putri(3), Dwijayanti Ngesthi Utami(4), Andayana Puspitasari Ghani(5*)

(1) Faculty of Pharmacy, Universitas Gadjah Mada
(2) Faculty of Pharmacy, Universitas Gadjah Mada
(3) Faculty of Pharmacy, Universitas Gadjah Mada
(4) Faculty of Pharmacy, Universitas Gadjah Mada
(5) Faculty of Pharmacy, Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Iron deficiency anemia is occurred due to lack of iron within the body, so that the amount of iron for erythropoiesis does not meet the requirement. Petai (Parkia speciosa Hassk) which is widespread in Indonesian archipelago, contain high existence of iron is supposed to be able to increase hemoglobin level in white mouse blood (Rattus norvegicus). The research was carried out by using petai from Wonosari whose made to dry extract by using freezedryer. Petai seed extract (Parkia speciosa Hassk.) injected to Wistar rat (Rattus norvegicus). Data analysis was using One Sample t-Test and ANOVA test in order to find out the effect of the doses towards pharmacological effect. The result showed that petai seed extract (Parkia speciosa Hassk) gave effect towards the enhancement of hemoglobin level (Hb) within white mouse blood (Rattus norvegicus). However, the optimum dosage was not able to be determined yet.


Keywords


Petai (Parkia speciosa Hassk), hemoglobin level, anemia



References

Cooper, MJ., Cockell, KA., and L’Abbe, M.R,. 2006. The Iron Status of Canadian Adolescent and Adults: Current Knowledge and Practical Implication. Canadian Journal of Dietetic Practice and Research. Vol 67: No.3

Fairbanks V.F., and Beutler E,. 1998. Iron deficiency. In : Beutlher E, MA Lichtman, BS Coller and TJ Kipps., editors, William Hematology. 6th ed. Mc Graw-Hill inc. New York

Ferreira, MU., Nunes, MS., Bertolino, CN., and Malafronte, RS,. 2007. Anemia and Iron deficiency in School Chlidren, Adolescent, and Adults: A Comunity-Based Study in Rural Amazonia. American Journal of Public Health. Vol 97: No. 2

Heni, T,. 2010 . Mengenal Lebih Jauh Tentang Petai. http://henithree.student.umm.ac.id/2010/01/21/mengenal-lebih-jauh-tentang-petai/. Diakses pada tanggal 19 Oktober 2013

Hoffbrand, A. V., J. E. Pettit., P. A. H. Moss. 2005. Kapita Selekta Haemotologi Edisi 4. EGC Penerbit Buku Kedokteran. Jakarta : hlm 1-3

Lee, HS., Kim, MS., Kim, YJ., and Kim, WY,. 2006. Iron status and its European Journal of Clinical Nutrition. vol. 60; 1130-1135

Mohamed S., Shamsuddin ABD Md., Rehman, Sulaiman S. and Abdullah F. 1987. Some nutritional and anti nutritional components in jering (pithecellobium jeringa), kerdas (pithecellobium icrocarpum) and association with pregnancy outcome in Korean pregnant women. petai (parkia speciosa). Pertanika, 10(1), 61-68

Patimah, S. 2007. Pola Konsumsi Ibu Hamil dan Hubungannya Dengan Kejadian Anemia Defisensi Besi. Jurnal Penelitian Kesehatan. Fakultas Kedokteran. Jakarta: hlm.8-9

Soegijanto, S. 2004. Penyakit Tropis dan Infeksidi Indonesia Jilid 2. Airlangga University Press . Surabaya: hlm.1-3

Winarno , F.,G., 2004. Kimia Pangan Dan Gizi. PT Gramedia Utama. Jakarta



DOI: https://doi.org/10.22146/tradmedj.8140

Article Metrics

Abstract views : 3435 | views : 16529

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2015 Majalah Obat Tradisional

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

©Majalah Obat Tradisional (Traditional Medicine Journal)
 ISSN 2406-9086
Faculty of Pharmacy
Universitas Gadjah Mada