Correlating Color and The Chemical Profiles of Sterculia quadrifida Barks for Herbal Raw Materials Quality

Triana Hertiani(1*), Siswandi Siswandi(2), Agrita Eka Pratiwi(3), Aryaningtyas Widya Pamungkas(4), Amanda Rumondang(5), Tsania Andaya Rodiata(6), Sekar Ayu Pratiwi(7), Caterina Siskadewi Lay(8), Ikra Agustina(9)
(1) Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Gadjah Mada. Jl. Sekip Utara, Sleman 55281, Yogyakarta
(2) Research Center for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency, Cibinong Science Center, Jalan Raya Jakarta, Cibinong, West Java 16915
(3) Master in Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara, Sleman, Yogyakarta 55281
(4) Master in Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara, Sleman, Yogyakarta 55281
(5) Master in Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara, Sleman, Yogyakarta 55281
(6) Master in Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara, Sleman, Yogyakarta 55281
(7) Master in Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara, Sleman, Yogyakarta 55281
(8) Master in Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara, Sleman, Yogyakarta 55281
(9) Master in Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara, Sleman, Yogyakarta 55281
(*) Corresponding Author
Abstract
The traditional use of faloak (Sterculia quadrifida R. Br.) stem bark as an effective treatment for various diseases has led to its widespread cultivation and collection. Therefore, this study aims to determine the correlation between the intensity and color variation of faloak stem bark with its antioxidant activity and phytochemical content using chemometrics analysis. The study procedures were carried out by collecting samples from different locations in East Nusa Tenggara, Indonesia. Stem bark intensity and color variations were then associated with chemical profiles of extract produced. Chemical profiles analyzed were Total Phenolic Content (TPC), Total Flavonoid Content (TFC), and antioxidant activity as measured using the DPPH, b-carotene bleaching, and CUPRAC methods. Subsequently, the data were subjected to multivariate statistical analyses utilizing Principal Component Analysis (PCA) and Cluster Analysis (CA). The results showed that color variations on faloak stem bark had no significant impact on cluster formation. CA and PCA showed grouping according to gray value representing color intensity. Meanwhile, PCA revealed significant correlations between gray value of faloak stem bark extract and TPC, antioxidant activity, and extract yield, with TFC having no association. Based on these results, color detection system could be developed to facilitate S. quadrafida bark collection as herbal medicine raw materials in the field.
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