Cohort Study in Outcome and One-Year Mortality of Acute Stroke Patient in Academic Hospital Universitas Gadjah Mada

https://doi.org/10.22146/ahj.v6i1.94520

Fajar Maskuri(1*), Humaera Elphananing Tyas(2), Nimitta Talirasa(3), Arni Wiastuti(4), Fathiya Akhsani(5), Yanasta Yudo Pratama(6)

(1) Academic Hospital UGM
(2) Academic Hospital UGM
(3) Academic Hospital UGM
(4) Academic Hospital UGM
(5) 
(6) Universitas Islam Indonesia
(*) Corresponding Author

Abstract


Background: Stroke is still becoming one of the most common non-communicable diseases in Indonesia. Sample Registration System survey in 2016 showed that in Indonesia stroke has become the most common cause of death at all age, about 19.9%. 4 Research conducted by Novbakht found that age, sex, BMI, type of stroke, family history of stroke, hyperlipidaemia, diabetes, and severity of stroke was related and increased the mortality rate. 6 Academic Hospital Universitas Gadjah Mada had not conducted this type of research, so that researcher wanted to know the one-year mortality rate after stroke, factors that related to mortality, and to improve the quality of stroke treatment at Academic Hospital Universitas Gadjah Mada.

Objective: To know one-year mortality rate in acute stroke patients in Academic Hospital Universitas Gadjah Mada by looking for the acute stroke characteristic, outcome of stroke patients, and risk factors that cause mortality in stroke patients.

Method: This is an analytic research using retrospective cohort study through data collection of acute stroke patients (patients with <5 days stroke onset) during July 2019 until June 2022 then we followed up the condition in the first year after stroke by using medical records, direct examination, or via telephone or video call. Mortality rates were assessed one year after stroke and the predictors of death were evaluated using the cox proportional hazard model.

Result: One-year mortality after stroke in our study were related to age (>67 years old) (OR=2,29; 95% CI 1,18-4,46; p=0,015) and the severity of stroke was related to higher NIHSS score (NIHSS score during admission 16-42, (OR=38,49; 95% CI 8,92-166,0; p<0,001)) and ICU admission ((OR=8,01; 95% CI 4,03-15,90; p<0,001)).  

Conclusion: An association was found between stroke severity and one-year outcomes of acute stroke patients with old age (>67 years), high NIHSS scores, and ICU admissions


Keywords


Acute Stroke, Mortality, Outcome, Infarct Stroke, Haemorrhagic Stroke, NIHSS, MRS

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References

Setyopranoto, I., Bayuangga. H., Panggabean. A., Alifaningdyah, S., Lazuardi, L., Dewi, F., et al., 2019. Prevalence of Stroke and Associated Risk Factors in Sleman District of Yogyakarta Special Region, Indonesia. Stroke Research and Treatment:1-8. 2. Virani, S., Alonso, A., Benjamin, E., Bittencourt, M., Callaway, C., Carson, A., et al, 2020. Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association. Circulation;141(9). 3. Siswanto, 2018. Hasil Utama Riset Kesehatan Dasar (RISKESDAS) 2018. Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI. 4. Usman, Y., Iriawan, R.W., Rosita, T., Lusiana, M., Kosen, S., Kelly, M., et al., 2019. Indonesia’s Sample Registration System in 2018: A Work in Progress. Journal of Population and Social Studies;27(1):39-52. 5. Nambiar,V., Raj, M., Vasudevan, D., Bhaskaran, R., Sudevan, R.2022. One- year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, India. BMJ Open 2022;12:e061258. doi:10.1136/ bmjopen-2022-061258. 6. Novbakht, H., Shamshirgaran, S.M., Sarbakhsh, P. 2020. Predictors of long term mortality after first ever stroke. Journal of Education and Health Promotion February 2020 Vol 9: 1-8 7. Appelros, P., Nydevik, I., Viitanen, M. 2003. Poor outcome after first ever stroke Predictor for death , dependency and recurrent stroke within the first year. . (Stroke. 2003;34:122-126.) 7. Appelros, P., Nydevik, I., Viitanen, M. 2003. Poor outcome after first ever stroke Predictor for death , dependency and recurrent stroke within the first year. Stroke. 2003;34:122-126. 8. Abdo, R., Abboud, H., Salameh, P., El Hajj, T., Hosseini, H. 2018. Mortality and predictor of death post stroke: Data from a multicenter prospective cohort of Lebanese stroke patients. Journal of Stroke and Cerebrovascular disease Vol 28, issue 4, April 2019, Pages 859-868. 9. Qurbany ZT, Wibowo A. 2016. Stroke Hemoragik e.c Hipertensi Grade II. Jurnal Medula Unila. 5(6): 114-118 10. Handayani D, Dominica D. 2018. Gambaran Drug Related Problems (DRP’s) pada Penatalaksanaan Pasien Stroke Hemoragik dan Stroke Non Hemoragik di RSUD Dr M Yunus Bengkulu. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia. 5(1): 36-44. 11. Lyden, Patrick. Using the National Institutes of Health Stroke Scale. Stroke American Heart Association. (Stroke. 2017;48:513-519. DOI: 10.1161/STROKEAHA.116.015434.) 12. Sulter G, Steen C, Keyser J. Use of the Barthel Index and Modified Rankin Scale in Acute Stroke Trials. Stroke American Heart Association. (Stroke. 1999;30:1538-1541.) 13. Carval T, Garret C, Guillon B. Outcomes of patients admitted to the ICU for acute stroke: a retrospective cohort. BMC Anesthesiology. (BMC Anesthesiology (2022) 22:235) https://doi.org/10.1186/s12871-022-01777-4 14. Namale G, Kamacooko O, Makhoba A. Predictors of 30-day and 90-day mortality among hemorrhagic and ischemic stroke patients in urban Uganda: a prospective hospital-based cohort study. Namale et al. BMC Cardiovascular Disorders (2020) 20:442 https://doi.org/10.1186/s12872-020-01724-6 15. Ferrone S. Boltyenkov A, Lodato Z. Clinical Outcomes and Costs of Recurrent Ischemic Stroke: A Systematic Review. Journal of Stroke and Cerebrovascular Diseases, Vol. 31, No. 6 (June), 2022: 106438 https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106438 16. Kang K, Park J, Ryu W. Body mass index and waist circumference as predictors of recurrent vascular events after a recent ischemic stroke. Journal of Stroke and Cerebrovascular Diseases, Vol. 32, No. 9 (September), 2023: 107221 https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107221 17. Ovbiagele B, Bath PM, Cotton D, Vinisko R, dan Diener HC. Obesity and Recurrent Vascular Risk After a Recent Ischemic Stroke. Stroke, Vol. 42, 2011: 3397–3402 18. Kubo S, Hosomi N, Hara N. Ischemic Stroke Mortality Is More Strongly Associated with Anemia on Admission Than with Underweight Status. Journal of Stroke and Cerebrovascular Diseases, Vol. 26, No. 6 (June), 2017: pp 1369–1374 http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.02.016



DOI: https://doi.org/10.22146/ahj.v6i1.94520

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