Determinan ketidakpatuhan terapi antiretroviral pada ODHA dewasa
Zulpahmi Harahap(1*), Eggi Arguni(2), Theodola Baning Rahayujati(3)
(1) Dinas Kesehatan Provinsi Kepulauan Riau
(2) RSUP Dr. Sardjito
(3) Dinas Kesehatan Kulon Progo
(*) Corresponding Author
Abstract
Determinants of non-adherence to antiretroviral therapy in adults with HIV/AIDS
Purpose
This study aimed to determine the factors of non-adherence ARV therapy in adult PLWHA.
Methods
A case-control study was conducted using secondary data of the Cilacap VCT clinic with consecutive sampling technique. The total sample was 204, consisting of 102 cases and 102 controls (1:1). The cases were adult PLWHA who did not adhere to ARV therapy and the controls were adult PLWHA who adhere to ARV therapy. The bivariate analysis used Chi-square and Fisher's exact tests and multivariate analysis used logistic regression tests.
Results
The variables that were shown to jointly affect non-adherence to ARV therapy in adult PLWHA were the level of education, CD4 count, PMO and opportunistic infections.
Conclusions
The risk factors of non-adherence to ARV therapy in adult PLWHA were the level of education, PMO, CD4 count and opportunistic infections. There needs to be a special assistance and counseling program on a regular basis to PLWHA adults with low education, obligating all PLWHA adults that start ARV therapy to have a PMO, continue HIV screening programs to entire population at risk and advocate the local governments to facilitate PLWHA who can not afford to obtain CD4 test .
Keywords
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- Depkes RI. Situasi HIV/AIDS di Indonesia Tahun 1987-2006. Jakarta; 2006.
- Dinas Kesehatan Kabupaten Cilacap. Situasi HIV/AIDS di Kabupaten Cilacap Tahun 2014. Cilacap; 2015.
- Loue S. Mental Health Practitioner’s Guide to HIV/AIDS. New York: Springer; 2013.
- O’Brien R. A Caution Regarding Rules of Thumbs for Variance Inflation Factors, Quality & Quantity. 2007. 673-690 p.
- Roura M, Busza J, Wringe A, Mbata D, Urassa M, Zaba B. Barriers to sustaining antiretroviral treatment in Kisesa, Tanzania: a follow-up study to understand attrition from the antiretroviral program. AIDS Patient Care STDS. Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA; 2009 Mar;23(3):203–10.
- Ubra R. Faktor-faktor yang berhubungan dengan pengobatan minum ARV pada pasien HIV di Kabupeten Mimika, Provinsi Papua. Universitas Indonesia; 2012.
- Chitangala F. A Case Control Study to Identify Factors That May Influence Antiretroviral Treatment Adherence. University of Zambia; 2007.
- Salami A., FWAC, Fadeyi A, FMCPATH, James A., MBBS, Desalu O, et al. Factors influencing adherence to antiretroviral medication in Ilorin, Nigeria. J Int Assoc Physicians AIDS Care. 2010;9(3):191–5.
- Wasti SP, Simkhada P, Randall J, Freeman J V, Teijlingen E Van. Factors Influencing Adherence to Antiretroviral Treatment in Nepal : A Mixed-Methods Study. 2012;7(5):1–11.
- Fithria. Faktor-faktor yang mempengaruhi tingkat kepatuhan pengobatan ARV pada ODHA di RSUD Tugurejo dan RSU Panti Wilasa Citarum, Semarang. Universitas Diponegoro; 2010.
- Mosoko J., Akam P., Weidle J., Brooks A., Aweh T., Kinge S, et al. Retention in an Antiretroviral Therapy Programme During an Era of Decreasing Drug Cost in Limbe, Cameroon. J Int AIDS Soc. 2011;14:32.
- Notoatmodjo S. Ilmu Perilaku Kesehatan. Jakarta: Rineka Cipta; 2011.
- Hansana V, Sanchaisuriya P, Durham J, Sychareun V, Chaleunvong K, Boonyaleepun S, et al. Adherence to Antiretroviral Therapy ( ART ) among People Living With HIV ( PLHIV ): a cross-sectional survey to measure in Lao PDR. 2013;1–12.
- Agu K., Okojie O, Oqua D, Omonaiye O, Onuoha C, Isah M., et al. Medication Adherence and Risk Factors for Non-adherence Among Patients Taking Highly Active Antiretroviral Therapy. West African J Pharm. 2011;22(1):19–26.
- Yaya I, Landoh D., Saka B, Patchali P., Waswa P, Aboubakari A., et al. Predictor of adherence to antiretroviral therapy among people living with HIV and AIDS at the regional hospital of Sokode, Togo. Lab Sante Pulique (EA 3729), Aix-Marselle Univ Fr. 2013;
- Yone WW., Soh E, Kengne A., Balkissou A., Kuaban C. Non-adherence to antiretroviral therapy in Yaounder: Prevalence, determinants and the concordance of two screening criteria. J Infect Public Health. 2013;6:307–15.
- Weidle PJ, Wamai N, Solberg P, Liechty C, Sendagala S, Were W, et al. Adherence to antiretroviral therapy in a home-based AIDS care programme in rural Uganda. 2003;1587–94.
- Cahaya P. Pengaruh pelatihan dengan diskusi kelompok kecil terhadap pengetahuan, sikap dan keterampilan pengawas minum obat pada penderita TB Paru di Kabupaten Sleman. Universitas Gadjah Mada; 2004.
- Nursalam, Nurs N., Kurniawati N. Asuhan Keperawatan pada Pasien Terinfeksi HIV/AIDS. Jakarta: Salemba Medika; 2007.
- Widyanthini. Faktor-faktor yang berhubungan dengan loss to follow up pada ODHA yang menerima terapi ARV di klinik Amertha Yayasan Kerti Praja Bali Tahun 2002-2012. Universitas Udayana Bali; 2014.
- Depkes RI. Pedoman Nasional Perawatan Dukungan dan Pengobatan bagi ODHA. Jakarta: Direktorat Pemberantasan Penyakit Menular dan Penyehatan Lingkungan; 2003.
- Negash T, Ehlers V. Personal factors influencing patients adherence to ART in Addis Ababa, Ethiopia. J Assoc Nurse AIDS Care. 2013;24:530–8.
- Naidoo P, Peltzer K, Louw J, Matseke G, Mchunu G, Tutshana B. Predictors of tuberculosis ( TB ) and antiretroviral ( ARV ) medication non-adherence in public primary care patients in South Africa : a cross sectional study. 2013.
- Abuzaitoun O., Hanson I. Organ Specific Manifestation of HIV Disease in Children. Pediatr Clin North Am. 2013;47:24–109.
- Kemenkes RI. Pedoman Nasional Tatalaksana Klinis Infeksi HIV dan Terapi Antirteroviral Pada Orang Dewasa. Jakarta; 2011.
- Boyer S, Clerc I, Bonono C-R, Marcellin F, Bilé P-C, Ventelou B. Non-adherence to antiretroviral treatment and unplanned treatment interruption among people living with HIV/AIDS in Cameroon: Individual and healthcare supply-related factors. Soc Sci Med [Internet]. Elsevier Ltd; 2011;72(8):1383–92. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0277953611001171.
- Markos E, Worku A, Davei G. Adherence to ART in PLWHA at Yirgalem Hospital, South Ethiopia. Ethiop J Heal Dev. 2006;22(2):175–9.
DOI: https://doi.org/10.22146/bkm.9825
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