Antimicrobial and Cytotoxic Potential of the Compound Secreted by Marine Bacteria Collected from the Karwar Coast, West Coast of India
https://doi.org/10.22146/ijbiotech.15991 Pradeep V. Khajure(1*), J. L. Rathod(2)
(1) Department of Studies and Research in Marine Biology, Karnatak University PG Center, Karwar, Karnataka, India
(2) Department of Studies and Research in Marine Biology, Karnatak University PG Center, Karwar, Karnataka, India
(*) Corresponding Author
Abstract
Antibacterial substances from sea sediment were isolated from marine environment of Karrwar, west
coast of India and characterized. Out of the 21 isolates subjected to secondary screening, 10 isolates were active
against Bacillus subtilis, 12 against Staphylococcus aureus, 6 against Escherichia coli, 3 against Proteus vulgaris and
4 against Salmonella typhi. Metabolites in the broth extract of overnight grown Pseudomonas spp. No.7 proved
to have antimicrobial and cytotoxic against human lung carcinoma cell
coast of India and characterized. Out of the 21 isolates subjected to secondary screening, 10 isolates were active
against Bacillus subtilis, 12 against Staphylococcus aureus, 6 against Escherichia coli, 3 against Proteus vulgaris and
4 against Salmonella typhi. Metabolites in the broth extract of overnight grown Pseudomonas spp. No.7 proved
to have antimicrobial and cytotoxic against human lung carcinoma cell
Keywords
Marine Bacteria; antimicrobial activity; cytotoxic activity; human lung carcinoma cells
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PDF DOI: https://doi.org/10.22146/ijbiotech.15991
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