Status iodium pada anak usia sekolah berdasarkan ekskresi iodium urin dan asupan iodium

Widya Ayu Kurnia Putri(1*), Dodik Briawan(2), Hidayat Syarief(3), Leily Amelia(4)

(1) Program Studi Ilmu Gizi, Fakultas Ilmu Ilmu Kesehatan, Universitas Jenderal Soedirman, Purwokerto
(2) Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, Institut Pertanian Bogor
(3) Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, Institut Pertanian Bogor
(4) Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, Institut Pertanian Bogor
(*) Corresponding Author


Iodine status in school-age children determined from iodine urine excretion and iodine intake

Background: School-age children are more at risk if they experience deficiencies and excess iodine. The concentration of iodine in urine is a good biomarker for assessing iodine intake, 90% of iodine intake will be excreted through urine.

Objective: This study aimed to analyze the iodine status of school-age children based on urinary iodine excretion (UIE) and iodine intake.

Method: The study design used a cross-sectional study on 44 healthy school-aged children in Bogor Regency. Subject selection was done purposively in healthy 5th-grade elementary school students. The data taken in this study was urine iodine excretion concentration and food recall (1x24 hours). Data were analyzed using descriptive analysis and Pearson correlation test.

Results: Median iodine excretion concentration in urine was 157 μg/l and the average daily iodine intake of children was 83.29 mg/day.

Conclusion: The concentration of iodine excretion in the urine of the children is in the category of sufficient iodine as recommended by WHO / UNICEF / ICCID while the daily intake of iodine for children is still in the less category. The results showed that there was no association of iodine daily intake with iodine excretion concentration in urine(p=0.469).


children; intake; iodine; UIE

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  1. Delange F. The role of iodine in brain development. Proc Nutr Soc. 2000;59(1):75–9. doi: 10.1017/s0029665100000094
  2. de Benoist B, McLean E, Andersson M, Rogers L. Iodine deficiency in 2007: global progress since 2003. Food Nutr Bull. 2008;29(3):195–202. doi: 10.1177/156482650802900305
  3. Andersson M, Karumbunathan V, Zimmermann MB. Global iodine status in 2011 and trends over the past decade. J Nutr. 2012;142(4):744–50. doi: 10.3945/jn.111.149393
  4. Zimmermann MB. Iodine deficiency. Endocr Rev. 2009;30(4):376–408. doi: 10.1210/er.2009-0011
  5. Andersson M, Takkouche B, Egli I, Allen HE, de Benoist B. Current global iodine status and progress over the last decade towards the elimination of iodine deficiency. Bull World Health Organ. 2005;83(7):518–25.
  6. Pearce EN, Andersson M, Zimmermann M. Global iodine nutrition—where do we stand in 2013?. Thyroid. 2013;23(5):523-8. doi: 10.1089/thy.2013.0128
  7. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes. Washington DC: National Academy Press; 2006.
  8. World Health Organization. Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers, 3rd ed. Geneva: WHO; 2007.
  9. Kementerian Kesehatan RI. Laporan hasil riset kesehatan dasar (Riskesdas) tahun 2013. Jakarta: Badan Penelitian dan Pengembangan Kesehatan, Republik Indonesia; 2013.
  10. Gordon RC, Rose MC, Skeaff SA, Gray AR, Morgan KM, Ruffman T. Iodine supplementation improves cognition in mildly iodine-deficient children. Am J Clin Nutr. 2009;90(5):1264–71. doi: 10.3945/ajcn.2009.28145
  11. Santiago-Fernandez P, Torres-Barahona R, Muela-Martinez JA, Rojo-Martinez G, Garcia-Fuentes E, Soriguer F, et al. Intelligence quotient and iodine intake: a cross-sectional study in children. J Clin Endocrinol Metab. 2004;89(8):3851–7. doi: 10.1210/jc.2003-031652
  12. Zimmermann MB, Connolly K, Bozo M, Bridson J, Rohner F, Grimci L. Iodine supplementation improves cognition in iodine-deficient school children in Albania: a randomized, controlled, double-blind study. Am J Clin Nutr. 2006;83(1):108–14. doi: 10.1093/ajcn/83.1.108
  13. Zimmermann MB. Iodine deficiency and excess in children: worldwide status in 2013. Endocr Pract. 2013;19(5):839–46. doi: 10.4158/EP13180.RA
  14. Chung HR. Iodine and thyroid function. Ann Pediatr Endocrinol Metab. 2014;19(1):8–12. doi: 10.6065/apem.2014.19.1.8
  15. Gibson RS. Principles of nutritional assessment, second edition. New York (NY): Oxford University Press; 2005.
  16. Kartono D, Samsudin M, Supadmi S. Asupan iodium anak sekolah di Indonesia. Gizi Indon. 2014;33(1):8-19.
  17. Zimmermann MB. Iodine deficiency and excess in children: worldwide status in 2013. Endocr Pract. 2013;19(5):839–46. doi: 10.4158/EP13180.RA
  18. Kartono D, Samsudin M, Supadmi S. Perkiraan asupan iodium dan natrium menggunakan urin 24 jam pada anak dan dewasa. Media Gizi Mikro Indonesia. 2014;5(2):71–84.
  19. Saggiorato E, Arecco F, Mussa A, Sacerdote C, Rossetto R, Origlia C, et al. Goiter prevalence and urinary iodine status in urban and rural/mountain areas of Piedmont region. J Endocrinol Invest. 2006;29(1):67–73. doi: 10.1007/BF03349179
  20. Duarte GC, Tomimori EK, de Camargo RY, Catarino RM, Ferreira JE, Medeiros-Neto G, et al. Excessive iodine intake and ultrasonographic thyroid abnormalities in school children. J Pediatr Endocrinol Metab. 2009;22(4):327–34. doi: 10.1515/jpem.2009.22.4.327
  21. Zimmermann MB, Ito Y, Hess SY, Fujieda K, Molinari L. High thyroid volume in children with excess dietary iodine intakes. Am J Clin Nutr. 2005;81(4):840–4. doi: 10.1093/ajcn/81.4.840
  22. Zou Y, Lou X, Ding G, Mo Z, Zhu W, Zhou J, et al. An assessment of iodine nutritional status and thyroid hormone levels in children aged 8–10 years living in Zhejiang Province, China: a cross-sectional study. Eur J Pediatr. 2014;173(7):929-34. doi: 10.1007/s00431-014-2273-y
  23. Fuse Y, Saito N, Tsuchiya T, Shishiba Y, Irie M. Smaller thyroid gland volume with high urinary iodine excretion in Japanese school children: normative reference values in an iodine sufficient area and comparison with the WHO/ICCIDD reference. Thyroid. 2007;17(2):145–55. doi: 10.1089/thy.2006.0209
  24. Kapil U. Excess iodine nutrition in Delhi. Indian Pediatr. 2010;47(10):894.
  25. Madukosiri CH, Esther I. Iodine content in diet and urine of people in imiringi and otuasega communities in Ogbia Lga, Bayelsa. Electronic Journal of Environmental, Agricultural and Food Chemistry. 2011;10(5):2216-21.
  26. Pehrsson PR, Patterson KY, Spungen JH, Wirtz MS, Andrews KW, Swanson CA, et al. Iodine in food- and dietary supplement–composition databases. Am J Clin Nutr. 2016;104(Suppl 3):868S–76S. doi: 10.3945/ajcn.115.110064


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