Cost Effectiveness Analysis Using Antibiotics of Cefixime and Cefotaxime for Diarrhea Patients at X Hospital in 2017

https://doi.org/10.22146/jmpf.36258

Gayatri Citraningtyas(1*), Ranny Inggrid Ruru(2), Amelia Nalang(3)

(1) Study Program of Pharmacy, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University
(2) Study Program of Pharmacy, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University
(3) Study Program of Pharmacy, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University
(*) Corresponding Author

Abstract


Diarrhea is a disease characterized by a change in the shape and consistency of stools, from soft to liquid, and increased frequency of bowel movements, which happen three times or more in a day. Different use of antibiotics by patients results in patient’s medical cost increase. The use of expensive antibiotics does not guarantee the effectiveness of patient care, therefore a research needs to be done to determine which antibiotic therapy is more cost effective between cefixime and cefotaxime antibiotics in hospitalized diarrhea patients in X hospital. This research was descriptive research with retrospective data retrieval. This research was conducted at Medical Record Installation and  Fund mobilization department of X hospital from November 2017 - Maret 2018. The samples in this study were 42 patients with 21 patients using Cefixime and 21 patients were using an Cefotaxime. Data was analyzed descriptively in table form. The results showed that the more cost-effective therapy between Cefixime and Cefotaxime in the treatment of diarrhea in X hospital was therapy with Cefixime antibiotic, which can be seen from ACER (Average Cost-Effectiveness Ratio) Cefixime Rp. 323.428,14/day compared with Cefotaxime ACER value of Rp. 477.180,26/day for each increase in effectiveness. The lowest ICER value on Cefixime was Rp. -50.565,8.-


Keywords


Analisis Efektivitas Biaya; Cefixime; Cefotaxime; Diare; Cost-effectiveness analysis; Cefixime; Cefotaxime; Diarrhea

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References

1. Setiawan I, Ani LS. Kejadian Diare Pada Balita Di Wilayah Kerja Puskesmas Tembuku Kabupaten Bangli Tahun 2016. E-Jurnal Med. 2017;6(5):12-20.

2. Trisnowati KE, Irawati S, Setiawan E. Kajian Penggunaan Antibiotik Pada Pasien Diare Akut Di Bangsal Rawat Inap Anak. Jurnal Manajemen dan Pelayanan Farmasi. 2017;7(1):16-23.

3. Dinkes Sulut. Profil Kesehatan Provinsi Sulawesi Utara 2016. Manado: Dinas Kesehatan Daerah Provinsi Sulawesi Utara; 2017.

4. Ruru,R.I., Citraningtyas,G., Uneputty,J.P., Analisis Efektifitas Biaya Pengobatan ISK Menggunakan Antibiotik Seftriakson Dan Siprofloksasin Di RSUP Prof. Dr. R.D. X Manado, Pharmacon, 2018; ISSN:2302-2493. 7(3) :42-51.

5. Septiani,S. Evaluasi Penggunaan Obat Pada Pasien Balita Terkena Diare Pada Pasien Rawat Inap Di Rumah sakit X Tahun 2014, Universitas Muhammadiyah Surakarta; 2015.

6. Trisnowati, K.E., Irawati S., Setiawan E. Kajian Penggunaan Antibiotik Pada Pasien Diare Akut Di Bangsal Rawat Inap Anak, Jurnal Manajemen Dan Pelayanan Farmasi, 2017; e-ISSN:2443-2946. 7(1) : 15-23

7. Khoirunnisa, S.M., Andayani, T.M., Inayati. Analisis Efektivitas Dan Biaya Penggunaan Zink Pada Anak Dengan Diare Akut Di Rumah Sakit PKU Muhammadiyah Yogyakarta Tahun 2011, Jurnal Manajemen Dan Pelayanan Farmasi, 2012; e-ISSN:2088-8137. 2(4) : 250-257.

8. Okafor, C.E., Ekwunife, O.I. Cost-Effectiveness Analysis Of Diarrhoea Management Approaches In Nigeria : A Decision Analytical Model, PLOS Neglected Tropical Diseases, 2017; DOI:0006124. 11(12) : 1-14.

9. Nalang,A., Citraningtyas,G., Lolo,W.A., Analisis Efektifitas Biaya Pengobatan Pneumonia Menggunakan Antibiotik Seftriakson Dan Sefotaksim Di RSUP Prof., Dr. R. D. X Manado, Pharmacon, 2018; ISSN:2302-2493. 7(3) : 321-329.

10. Salamah,U. Analisis Cost-Effectiveness Penggunaan Antibiotik Pada Pasien Pneumonia Pediatrik Di Instalasi Rawat Inap RSUD Dr. Moewardi Surakarta Tahun 2016. Universitas Muhammadiyah Surakarta; 2017.

11. Wulandari. Penanganan Diare di Rumah Tangga Merupakan Upaya Menekan Angka Kesakitan Diare Pada Balita, Universitas Negeri Gorontalo;2012.

12. Numlil, K. T., Betti G., Wulandari A. Evaluasi Penggunaan Obat Diare Terhadap Kesesuaian Obat dan Dosis Pada Pasien Anak Rawat Inap Di Rumah Sakit Umum Daerah (RSUD) Budhi Asih Jakarta, Farmasains UHAMKA, 2012,; 5(1): 241-242.

13. Sari, A., dan Rahmawati,E.Evaluasi Pemberian Antibiotik Pada Pasien Anak Diare Spesifik Di Instalasi Rawat Inap RS PKU Muhammadiyah Yogyakarta, Prosiding Rakernas dan Pertemuan Ilmiah Tahunan, 2016; e-ISSN:2541-0474.

14. Sugiharto, B. Kromosom Manusia. Yogyakarta: UGM; 2010.

15. Kereh, M.J.B. Analisis Efektivitas Biaya Pengobatan Pasien Pediatrik Demam Tifoid Menggunakan Cefixime Dan Cefotaxime Di RSU Pancaran Kasih GMIM Manado. Jurnal Pharmacon. 2018;7 (2):17-27.

16. Lorensia, A., dan Doddy D.Q. Farmakoekonomi, Edisi Kedua, Surabaya: Ubaya Press ;2016.



DOI: https://doi.org/10.22146/jmpf.36258

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