PENGARUH FASCIOLOSIS PADA SAPI BALI TERHADAP KADAR SERUM GLUTAMIC PYRUVIC TRANSAMINASE (SGPT) DAN ALKALINE PHOSPHATASE (ALP)

https://doi.org/10.22146/jsv.40719

Amirullah Amirullah(1), Dradjat AS(2*), Sriasih M(3), Maskur Maskur(4), Depamede SN(5), Kisworo D(6), Kurniasih Kurniasih(7)

(1) Medik Veteriner Muda, Balai Karantina Pertanian Kelas I Mataram NTB
(2) Pasca Sarjana (Magister Manajemen Sumberdaya Peternakan), Fakultas Peternakan, Universitas Mataram
(3) Pasca Sarjana (Magister Manajemen Sumberdaya Peternakan), Fakultas Peternakan, Universitas Mataram
(4) Pasca Sarjana (Magister Manajemen Sumberdaya Peternakan), Fakultas Peternakan, Universitas Mataram
(5) Pasca Sarjana (Magister Manajemen Sumberdaya Peternakan), Fakultas Peternakan, Universitas Mataram
(6) Pasca Sarjana (Magister Manajemen Sumberdaya Peternakan), Fakultas Peternakan, Universitas Mataram
(7) Fakultas Kedokteran Hewan Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Investation of Fasciola sp. On several species of cattle in Indonesia has occurred since a long time ago. Fasciolosis caused a high economical loss such as decreasing of carcass and organs, sometimes caused death of calves. The objectives of the research were to evaluate the effect of fasciolosis on Serum Glutamic Piruvic Transaminase  (SGPT), and  obstruction of  bile duct by Alkaline Phosphatase (ALP) in Bali cattle suffered from fasciolosis. Feces of Bali cattle raised in endemic areas of fasciolosis were examinated by sedimentation test to identify eggs per gram of faeces (EPG) of Fasciola sp. The blood samples of cattle which positive to fasciolosis were use to study the hematology by autoanalyser (HCLAB Easy access &SYSMEX KX-2), SGPT (ILab 300 Plus Chemistry System) and ALP (IL 300 Plus Chemistry).  The results of research showed that from 89 head, 28 were infested of Fasciola sp whithin of 7-115 epg (min-max). From 20 fasciolosis cattle indicated that MCHC of 90%, RBC of 30%, HB of 20%,  and  eosinophils of 2 % of cattle were lower than that of normal standard, while  lymphocytes of 60%, MCV of 40%, ALP of 10%  and SGPT of 5% of cattle were higher than that of normal standart. It can be concluded that hematological appearances of cattle suffered from fasciolosis had macrocytic hypochromic anemia, eosinopenia, limphocytosis. The increase of SGPT showed the damage of liver by young liver flukes, and the increase of ALP was caused by the obstruction of bile duct by mature liver flukes.

Key word: ALP, Cattle, Fasciolosis, Hematology, SGPT.


Keywords


ALP; Cattle; Fasciolosis; Hematology; SGPT;Fasciolosis; Hematologi; Sapi



References

Adama, J.Y., O.J. Ajanusi, N. Chiezey, A. Lawal. 2011. Biochemical responses of yankasa sheep to experimental fasciola gigantica infection in Zaria, Nigeria. Int. J. anim. veter. adv., 3(6): 409-415. Aghaei, S., A. Farahnak, T. Golmohammadi, M. Eshraghian, M. Molaeirad. 2017. In Vitro Assay Of Alkaline Phosphatase Enzyme Activity In Fasciola Infected Livers and Fasciola Hepatica Parasite. JPS. Vol8, No3. Pp: 13-17. Astiti, L.G.S and T. Panjaitan. 2012. Mapping Of Fascioliasis On Bali Cattle In Lombok International Conference on Livestock Production and Veterinary Technology PP: 416-42. Chauvin, A., G. Bouvet, C. Boulard. 1995. Humoral And Cellular Immune Responses To Fasciola Hepatica Experimental Primary And Secondary Infection In Sheep. Int J Parasitol. 25(10):1227-41. Cyntia, M.K., S. Line, S.E. Aiello. 2010. Merck Veterinay Manual, 10th ed. 3239 Satellite Blvd., Duluth, Ga 30096. Dharmayudha, A.A.G.O., I.B.D Kusumadarma, I.B.K. Ardana, M.S. Anthara, I.W.N.F. Gunawan, L.M. Sudimartini, K.K. Agustina. 2018. Aktivitas Alanin Aminotransferase dan Aspartat Aminotransferase Sapi Bali Terinfeksi Fasciola Gigantica. Bulvet. 2008 vol 10 No.1:87-92. http://ojs.unud.ac.id/index.php/buletinvet. Edith, R., R. Godara, R.L. Sharma, M.B. Thilagar. 2010. Serum Enzyme And Hematological Profile Of Fasciola Gigantica Immunized And Experimentally Infected Riverine Buffaloes. P R.Volume 106, Issue 4, pp 947–956. Egbu, M.I.Florence., O.P. Ubachukwu, C.I. Okoye. 2013. Haematological Changes Due to Bovine Fascioliasis. Afr. J. Biotechnol., Vol. 12 (15), pp.1828-1835. Estuningsih, S.E., S. Widjajanti, G. Adiwinata. 2003. Perbandingan antara uji elisa-antibodi dan pemeriksaan telur cacing untuk mendeteksi infeksi Fasciola gigantica pada sapi. JITV 9(1): 55-60. Fraser, A., M. Longnecker, D. Lawlor. 2007. Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999–2004. Gastroenterology. 133: 1814–1820. Ganguly, A., R.S. Bisla, S.S. Chaudhri. 2016. Haematological And Biochemical Change In Ovine Fasciolosis. Haryana vet. No: 55, Page: 27-30. Gowda, S., P.B. Desai, V.V. Hull, A.A.K. Math, S.N. Vernekar, S.S. Kulkarni. 2009. A review on laboratory liver function tests. Pan. Afr. Med. J. 3(17): 1-11. George, J.W., J. Snipes, V.M. Lane. 2010. Comparison Of Bovine Hematology Reference Intervals From 1957 to 2006. Vet Clin Pathol 39: 138-148. Hambal, M., S. Arman, D. Agus. 2013. Tingkat Kerentanan Fasciola gigantica pada Sapi dan Kerbau di Kecamatan Lhoong, Kabupaten Aceh Besar.JMV vol.7. Hal ; 49-53 Hodzic, A., A. Zuko, R. Avdic, R. Alic, J. Omeragic, A. Jazic. 2013. Influence Of Fasciola Hepatica On Serum Biochemical Parameters And Vasculer Biliary System Of Sheep Liver. Iranian J. Parasitol. 8: 92-98. Lotfollahzadeh, S., M. Mohri, ShR. Bahadori, M.R. Dezfouly, P. Tajik. 2008. The Relationship Between Normocytic, Hypochromic Anaemia And Iron Concentration Together With Hepatic Enzyme Activities In Cattle Infected With Fasciola Hepatica. J Helminthol. doi: 10.1017/S0022149X07874232.82(1) :85-88. Love, S. and G. Hutchinson. 2007. Wormtest For Livestock And Guide To Egg Counts. Profitable and Suistainable Primary Industries. Primefact 480 (Replaces Agnote Dai-308) 2-4. Macer, V.J. 2003. Veterinary Clinical Laboratory Tecniques. VET 24. Martindah, E., S. Widjajanti, S.E. Estuningsih, Suhardono. 2005. Meningkatkan kesadaran dan kepedulian masyarakat terhadap fasiolosis sebagai penyakit zoonosis. Wartazoa 15: 143-154. Mehmod, K., H. Zhang, A.J. Sabir, R.Z. Abbas, M. Ijaz, A.Z. Durrani, M.H. Saleem, M.Ur Rehman, M.K. Iqbal, Y. Wang, H.I. Ahmad, T. Abbas, R. Hussain, M.T. Ghori, S. Ali, A.U. Khan, Li. Jiakui. 2017. A Review On Epidemiology, Global Prevalence And Economical Losses Of Fasciolosis In Ruminants. Microbial Pathogenesis 109; 253-262. Munadi. 2011, Tingkat Infeksi Cacing Hati Kaitannya Dengan Kerugian Ekonomi Sapi Potong yang Disembelih di Rumah Potong Hewan Wilayah Eks-Kresidenan Banyumas Agripet : Vol (11) No. 1: 45-50. Pfukenyi, D.M., S. Mukaratirwa, Lii. Willingham, A.L.S. Monrad. 2006. Epidemiological Studies of Fascila gigantica Infections In Cattle In The Highveld And Lowveld Communal Grazing Areas Of Zimbabwe. Onderstepoort. JVR 73(1), 37-51. Shichibi.T.H. 2017. Study on the Prevalence and Economic Importance of Bovine Fasciolosis in Mizan Teferi Municipal Abattoir, SEWASJ 35 (2): 182-187, 2017. Suchit, S. P., J. J. Hasnani, P. V. Patel, C. J. Dave, R. Shukla, N. D. Hirani. 2015. Study on Haemato-Biochemical Alterations Occurred in Fasciola spp. Infected. IJMRD 2015; 2(3): 756-759. Taylor, M. A., R. L. Coop, R. L. Wall. 2016. Veterinary Parasitology. 4th Edition UK: Blackwell Publishing. Usib, L. P. E., E. S. Ibanga, H. J. Edoho, E. E. Amadi, E. Utah. 2014. Prevalence of Fascioliasis and the economic loss of condemned liver due to Fasciola infection in Cattle slaughtered at three abattoirs in Eket Urban, Akwa Ibom State of Nigeria. Global Advanced Research JFST, 3(2): 54-75. Wiedosari. E., H. Hayakawa, B. Copeman. 2006. Host differences in response to trickle infection with Fasciola gigantica in buffalo, Ongole and Bali calves. Trop. Anim. Health Prod. 38:43-53. WHO. 2007. World Health Organisation. Report of the WHO Informal Meeting on use of triclabendazole in fascioliasis controls. WHO/CDS/PCT/2007. Whitlock, J. 2017. Liver Enzymes and Liver Function Tests and Results. The American Association of Clinical Chemistry. http://www.labtestsonline.org/understanding/analytes/liver_panel/glance.html. Zhang, W. Y., M. Moreau, B. Z. Yang, Z. Q. Li, J. C. C. Hope, J. Howard, Y. W. Huang. 2006. Humoral And Cellular Immune Responses To Fasciola Gigantica Experimental Infection In Buffaloes. Research In Vet. Sc Volume 80, Page 299-307.



DOI: https://doi.org/10.22146/jsv.40719

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