Faktor Risiko Potensial terhadap Canine Leptospirosis di Ragunan Animal Hospital Jakarta, Indonesia


Ambar Retnowati(1*), Agustin Indrawati(2), Upik Kesumawati Hadi(3), Safika .(4), Pratitis S Wibowo(5), Susan M Noor(6)

(1) Program Studi Kesmavet Fakultas Kedokteran Hewan Institut Pertanian Bogor
(2) Departemen IPHK Fakultas Kedokteran Hewan Institut Pertanian Bogor
(3) Departemen IPHK Fakultas Kedokteran Hewan Institut Pertanian Bogor
(4) Departemen IPHK Fakultas Kedokteran Hewan Institut Pertanian Bogor
(5) Rumah Sakit Hewan Jakarta Ps. Minggu Jakarta
(6) Laboratorium Bakteriologi Balai Besar Penelitian Veteriner Bogor
(*) Corresponding Author


Leptospirosis is a zoonotic disease caused by bacteria Leptospira sp. which causes infection in animals and humans. Dogs infected with leptospirosis showed symptoms such as anorexia, fever, vomiting, weakness, diarrhea and often experience yellowing of the eye area and mucosa around the mouth (icteric) with fatal systemic complications and multi-organ dysfunction, especially in the kidneys and liver. Leptospirosis is an endemic disease in Jakarta. This study aims to identify risk factors that can contribute to canine mortality based on early clinical symptoms that are found when the dog is in an animal health service facility such as a veterinary clinic, veterinary hospital or independent practice veterinarian. Method were used in this study is clinical manifestations and laboratory examinations and medical records of dogs with suspected leptospirosis. Criteria inclusion were based on aspects of the clinical symptoms of dogs in and around Jakarta. Analysis data used the chi-square with confidence of interval (CI) 95%. Dogs used during the study had ages for puppies (less than 1 year) totaling 13 or 32.50%, for adult dogs over 1 year amounted to 27 or 67.50%, 80% male dogs and 20% female. with 80% maintenance system not housed by the owner. Risk factors for clinical symptoms such as myalgia, symptomatic vomiting of the pulmonary area or shortness of breath and abdominal pain, conjunctival suffusion, anorexia and diarrhea contributed to the high mortality rate leptospirosis during study in dogs 2020.


Canine; Clinical symptoms; Leptospirosis; Mortality; Risk factors

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Budiharta, S dan Suardana I.W. (2002). Epidemiologi dan Ekonomi Veteriner. PenerbitUdayanaBali.https://scholar.google.co.id/scholar?oi=bibs&cluster=9628917383055217777&btnI=1&hl=en javascript:void(0). Brown, C. A., Roberts, A. W., Miller, M. A., Davis, D. A., Brown, S. A., Bolin, C. A., Jarecki-Black, J., Greene, C. E., & Miller-Liebl, D. (1996). Leptospira interrogans serovar grippotyphosa infection in dogs. Journal of the American Veterinary Medical Association, 209(7), 1265–1267. Desvars A, Cardinale E, Michault, A. (2011). Animal leptospirosis in small tropical areas. Epidemiology and Infection,Vol.139(2):167-188. Edwards, C. N., & Levett, P. N. (2004). Prevention and treatment of leptospirosis. Expert Review of Anti-Infective Therapy, 2(2), 293–298. https://doi.org/10.1586/14787210.2.2.293 Greenlee, J. J., Bolin, C. A., Alt, D. P., Cheville, N. F., & Andreasen, C. B. (2004). Clinical and pathologic comparison of acute leptospirosis in dogs caused by two strains of Leptospira kirschneri serovar grippotyphosa. American journal of veterinary research, 65(8), 1100–1107. https://doi.org/10.2460/ajvr.2004.65.1100 Goldstein, R. E., Lin, R. C., Langston, C. E., Scrivani, P. V., Erb, H. N., & Barr, S. C. (2006). Influence of infecting serogroup on clinical features of leptospirosis in dogs. Journal of veterinary internal medicine, 20(3), 489–494. https://doi.org/10.1892/0891-6640(2006)20[489:ioisoc]2.0.co;2 McCallum, K. E., Constantino-Casas, F., Cullen, J. M., Warland, J. H., Swales, H., Linghley, N., Kortum, A. J., Sterritt, A. J., Cogan, T., & Watson, P. J. (2019). Hepatic leptospiral infections in dogs without obvious renal involvement. Journal of veterinary internal medicine, 33(1), 141–150. https://doi.org/10.1111/jvim.15340 Gasem, M. H., Hadi, U., Alisjahbana, B., Tjitra, E., Hapsari, M., Lestari, E. S., Aman, A. T., Lokida, D., Salim, G., Kosasih, H., Merati, K., Laras, K., Arif, M., Lukman, N., Sudarmono, P., Lisdawati, V., Lau, C. Y., Neal, A., & Karyana, M. (2020). Leptospirosis in Indonesia: diagnostic challenges associated with atypical clinical manifestations and limited laboratory capacity. BMC infectious diseases, 20(1), 179. https://doi.org/10.1186/s12879-020-4903-5 Greene GC, Sykes JE, Brown CA, Hartmann K. (2008). Leptospirosis. Dalam Greene CE Editor. Infection disease of dogs and cats. Missouri: Sounders Elsevier. page. 402-417. Harkin KR. (2012). Canine leptospirosis: A perpective on recent trend. Today Veterinary Practice 2(4): 27-33. [Kemenkes] Kementerian Kesehatan Republik Indonesia. (2019). Profil Kesehatan Indonesia 2018. Jakarta Klaassen, J. K. (1999). Reference Values in Veterinary Medicine. Laboratory Medicine, 30(3), 194–197. https://doi:10.1093/labmed/30.3.194 Levett, P. N. (2001). Leptospirosis Leptospirosis. Clinical Microbiology Reviews, 14(2), 296–326. https://doi.org/10.1128/CMR.14.2.296 Reagan, K. L., & Sykes, J. E. (2019). Diagnosis of Canine Leptospirosis. Veterinary Clinics of North America - Small Animal Practice, 49(4), 719–731. https://doi.org/10.1016/j.cvsm.2019.02.008 Sykes, J. E., Hartmann, K., Lunn, K. F., Moore, G. E., Stoddard, R. A., & Goldstein, R. E. (2011). 2010 ACVIM small animal consensus statement on leptospirosis: diagnosis, epidemiology, treatment, and prevention. Journal of veterinary internal medicine, 25(1), 1–13. https://doi.org/10.1111/j.1939-1676.2010.0654.x Ward, M. P., Glickman, L. T., & Guptill, L. E. (2002). Prevalence of and risk factors for leptospirosis among dogs in the United States and Canada: 677 cases (1970-1998). Journal of the American Veterinary Medical Association, 220(1), 53–58. https://doi.org/10.2460/javma.2002.220.53 Ward, M. P., Guptill, L. F., Prahl, A., & Wu, C. C. (2004). Serovar-specific prevalence and risk factors for leptospirosis among dogs: 90 cases (1997-2002). Journal of the American Veterinary Medical Association, 224(12), 1958–1963. https://doi.org/10.2460/javma.2004.224.1958

DOI: https://doi.org/10.22146/jsv.60354

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