Formulation and Antibacterial Activity of Coffee Ground Waste Extract Face Serum
Arif Nur Ikhsan(1*), Hani Nabila Suryani(2), Anik Sri Ernawati(3), Celine Aurellia Chang(4), Purwanto Purwanto Purwanto(5)
(1) Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
(2) Undergraduate Program, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
(3) Undergraduate Program, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
(4) Undergraduate Program, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
(5) Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
(*) Corresponding Author
Abstract
Coffee is one of the most popular beverages around the World, which generates over million tons of coffee ground waste each year. Using technologies, the waste can be converted into value-added products such as cosmetic. The objective from this study is to formulate the coffee ground waste extract to face serum for anti-acne treatment. Samples are collected from several coffee shops, then macerated using ethanol. Formulation consisting: HPMC, tween 80, glycerin, PEG 400, sodium EDTA, sodium benzoate and triethanolamine. Evaluation is conducted to the extract antibacterial activity, face serum bacterial activity and face serum stability. The extract exhibits 0.860 gram/mL MIC50 Cutibacterium acnes, meanwhile, the face serum provides 15.30 ± 4.03 mm inhibition zone. Ultimately, the face serum is stable after 4 weeks testing using accelerated stability test in terms of organoleptic, pH and viscosity.
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Lee YG, Cho EJ, Maskey S, Nguyen DT, Bae HJ. Value-Added Products from Coffee Waste: A Review. Molecules. 2023;28(8):1-19. doi:10.3390/molecules28083562 2. Ludwig IA, Clifford MN, Lean MEJ, Ashihara H, Crozier A. Coffee: biochemistry and potential impact on health. Food Funct. 2014;5(8):1695-1717. doi:10.1039/C4FO00042K 3. Choi S, Jung S, Ko KS. Effects of coffee extracts with different roasting degrees on antioxidant and anti-inflammatory systems in mice. Nutrients. 2018;10(3). doi:10.3390/nu10030363 4. Usman HN, Pratiwi L, Wijianto B. Cosmetic Serum Loaded Arabica Coffee ( Coffea arabica ) Extract : Formulation and Antioxidant Study. 2023;28(August):93-101. doi:10.22146/mot.83120 5. Mojica BE, Fong LE, Biju D, et al. The Impact of the Roast Levels of Coffee Extracts on their Potential Anticancer Activities. J Food Sci. 2018;83(4):1125-1130. doi:10.1111/1750-3841.14102 6. Singh Arora D, Jeet Kaur G, Kaur H. Antibacterial activity of tea and coffee: Their extracts and preparations. Int J Food Prop. 2009;12(2):286-294. doi:10.1080/10942910701675928 7. Banki A, Castiglione FM. Infections of the Facial Skin and Scalp. Elsevier Inc.; 2015. doi:10.1016/B978-0-323-28945-0.00022-3 8. Burlando B, Verotta L, Cornara L, Bottini-Massa E. Herbal Principles in Cosmetics. CRC Press; 2010. doi:10.1201/EBK1439812136 9. Aggnihotri S. Formulation and development of botanicals-based herbal serum. Pharmaspire. 2021;13(4):211-217. www.isfcppharmaspire.com 10. Juniatik M, Hidayati K, Priskaningtyas Wulandari F, et al. FORMULATION OF NANOEMULSION MOUTHWASH COMBINATION OF LEMONGRASS OIL (Cymbopogon citratus) AND KAFFIR LIME OIL (Citrus hystrix) AGAINST Candida albicans ATCC 10231 FORMULASI MOUTHWASH NANOEMULSI KOMBINASI MINYAK SEREH (Cymbopogon citratus) DAN MINYAK JERUK. Tradit Med J. 2017;22(1):2017. 11. Pum J. A Practical Guide to Validation and Verification of Analytical Methods in the Clinical Laboratory. Vol 90. 1st ed. Elsevier Inc.; 2019. doi:10.1016/bs.acc.2019.01.006 12. Yosefa SR, Tandanu E, Leslie W, Fransisca S, Angie E, Yosefa SR. In Vitro and In Vivo Antidiarrheal Activity of Dragon Fruit Peels Methanolic Extract. 2023;28(August):77-85. doi:10.22146/mot.81216 13. Veiga A, Toledo M da GT, Rossa LS, et al. Colorimetric microdilution assay: Validation of a standard method for determination of MIC, IC50%, and IC90% of antimicrobial compounds. J Microbiol Methods. 2019;162(March):50-61. doi:10.1016/j.mimet.2019.05.003 14. Mytilinaios I, Salih M, Schofield HK, Lambert RJW. Growth curve prediction from optical density data. Int J Food Microbiol. 2012;154(3):169-176. doi:10.1016/j.ijfoodmicro.2011.12.035 15. Zhang X, Wang Y, Guo J, et al. Comparing two functions for optical density and cell numbers in bacterial exponential growth phase. J Pure Appl Microbiol. 2015;9(1):299-305. 16. Butterfield J, Lodise TP, Pai MP. Applications of Pharmacokinetic and Pharmacodynamic Principles to Optimize Drug Dosage Selection: Example of Antibiotic Therapy Management. Elsevier Inc.; 2012. doi:10.1016/B978-0-12-385467-4.00009-9 17. Poomanee W, Chaiyana W, Mueller M, Viernstein H, Khunkitti W, Leelapornpisid P. In-vitro investigation of anti-acne properties of Mangifera indica L. kernel extract and its mechanism of action against Propionibacterium acnes. Anaerobe. 2018;52:64-74. doi:10.1016/j.anaerobe.2018.05.004 18. Jantarat C, Sirathanarun P, Chuchue T, Konpian A, Sukkua G, Wongprasert P. In vitro antimicrobial activity of gel containing the herbal ball extract against propionibacterium acnes. Sci Pharm. 2018;86(1):1-9. doi:10.3390/scipharm86010008 19. Weber N, Biehler K, Schwabe K, et al. Hop extract acts as an antioxidant with antimicrobial effects against Propionibacterium acnes and Staphylococcus aureus. Molecules. 2019;24(2). doi:10.3390/molecules24020223 20. Hou HS, Bonku EM, Zhai R, et al. Extraction of essential oil from Citrus reticulate Blanco peel and its antibacterial activity against Cutibacterium acnes (formerly Propionibacterium acnes). Heliyon. 2019;5(12):e02947. doi:10.1016/j.heliyon.2019.e02947 21. Irianto IDK, Ismiyati, Witaningrum E, Ayuningtyas EN, Ulfah MM, Purwanto. Antibacterial activity of cream, ointment, and emulgel of Ocimum basilicum L. essential oil against Propionibacterium acnes. Maj Obat Tradis. 2023;28(1):40-47. doi:10.22146/mot.80909 22. Aulifa DL, Caroline M, Tristiyanti D, Budiman A. Formulation of the serum gel containing green coffee bean (Coffea robusta l) extract as an antioxidant and tyrosinase enzyme inhibitor. Rasayan J Chem. 2020;13(4):2346-2351. doi:10.31788/RJC.2020.1345866 23. Panontin JF, Barbosa R dos S, Isaac V, Seibert CS, Scapin E. Chemical composition, antioxidant activity and development of a facial serum formulation from the extract of Hancornia speciosa. Nat Prod Res. 2022;36(23):6121-6125. doi:10.1080/14786419.2022.2053968 24. Lourith N, Kanlayavattanakul M. Formulation and clinical evaluation of the standardized Litchi chinensis extract for skin hyperpigmentation and aging treatments. Ann Pharm Fr. 2020;78(2):142-149. doi:10.1016/j.pharma.2020.01.004 25. Rahman N, Rahman H, Haris M, Mahmood R. Antioxidant, anti-inflammatory and wound healing properties of ethanolic extracts of thevetia peruviana (Pers.) k. schum. Marmara Pharm J. 2019;23(1):101-113. doi:10.12991/jrp.2018.114 26. Al-Momani RM, Arabeyyat ZH, Malkawi EE, Al-Zibdah MK. Formulation and evaluation of herbal antioxidant face cream using extract of the marine seaweed Sargassum spp. (Phaeophyceae). J Res Pharm. 2022;26(4):828-833. doi:10.29228/jrp.180 27. Vora J, Srivastava A, Modi H. Antibacterial and antioxidant strategies for acne treatment through plant extracts. Informatics Med Unlocked. 2018;13(June 2017):128-132. doi:10.1016/j.imu.2017.10.005 28. Bhinge SD, Bhutkar MA, Randive DS, et al. Formulation and evaluation of polyherbal gel containing extracts of azadirachta indica, adhatoda vasica, piper betle, ocimum tenuiflorum and pongamia pinnata. Marmara Pharm J. 2019;23(1):44-54. doi:10.12991/jrp.2018.107 29. Demirbolat İ, Kartal M. Formulation, stability and analytical method validations of combined St. John’s wort and valerian root dry extracts in solid oral dosage forms. J Res Pharm. 2019;23(5):812-821. doi:10.35333/jrp.2019.29
DOI: https://doi.org/10.22146/farmaseutik.v19i3.90227
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