Pharmacological Activities, Isolated Compounds, Toxicity, and Potential for New Drug Discovery from the Genus Leea

  • Purwaniati Purwaniati Universitas Bhakti Kencana
  • Rahmana Emran Kartasasmita School of Pharmacy, Bandung Technology Institute, Jl. Ganesa No.10, Bandung, Indonesia
  • Muhammad Insanu School of Pharmacy, Bandung Technology Institute, Jl. Ganesa No.10, Bandung, Indonesia
  • Maria Immaculata Iwo School of Pharmacy, Bandung Technology Institute, Jl. Ganesa No.10, Bandung, Indonesia
Keywords: Genus Leea, pharmacological activity, toxicity

Abstract

The genus Leea is a genus of medicinal plants. Half of this genus species are traditionally used to treat various ailments. This genus also holds promise for molecules that have the potential to be used as drugs or lead compounds in the discovery of a new drug. So far, 66 compounds have been isolated from this genus, 46 known to have pharmacological activity. Antioxidant, antimicrobial, anti-inflammatory and anticancer are the pharmacological activities most frequently found in these compounds. Although the toxicity studies are still limited to chronic toxicity tests showing low toxicity potential. The fact that various pharmacological activities and low potential make toxicity makes this plant worthy of continued study. The potential to possibility drugs from this genus is also huge.

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Webpage:
The Plant List (2022, December 2). Genus Leea. Retrieved from http://www.theplantlist.org/tpl1.1/search?q=leea
Published
2024-03-25
How to Cite
Purwaniati, P., Kartasasmita, R. E., Insanu, M., & Iwo, M. I. (2024). Pharmacological Activities, Isolated Compounds, Toxicity, and Potential for New Drug Discovery from the Genus Leea. Indonesian Journal of Pharmacy, 35(1), 1-19. https://doi.org/10.22146/ijp.6654
Section
Review Article