VITAMIN C, VITAMIN A AND ALPHA HYDROXY ACID IN BENGKOANG (Pachyrhizus Erosus)

https://doi.org/10.22146/tradmedj.10726

Ardian Widyatmoko(1*), Dwi Hastutik(2), Ari Sudarmanto(3), Endang Lukitaningsih(4)

(1) Faculty of Pharmacy, Universitas Gadjah Mada, Jogjakarta
(2) Faculty of Pharmacy, Universitas Gadjah Mada, Jogjakarta
(3) Faculty of Pharmacy, Universitas Gadjah Mada, Jogjakarta
(4) Faculty of Pharmacy, Universitas Gadjah Mada, Jogjakarta
(*) Corresponding Author

Abstract


Bengkoang or Pachyrhizus erosus has been used as a traditional cosmetic material since many years ago. Until now, many cosmetic preparations using bengkoang as a main material have been produced by cosmetic industries, mainly for skin care, whitening and sunscreen preparation. However, content of vitamin A, vitamin C and alpha hydroxyl acid has not been discovered yet. These compounds are essential in skin care process because of their activities in cell regeneration, antioxidant as well as peeling of dead skin cell layer. The aim of this research is to provide information about the content of three compounds in bengkoang. Vitamin A has been analysed by spectrophotometer, vitamin C analysed using titration method and alpha hydroxyl acid analysed using gas chromatography. The result showed that concentrations of vitamin A and vitamin C are 179.21 ± 8.19 ppm and 0.31 ± 0.06 %, respectively. Meanwhile the content of alpha hydroxyl acid was 0.80 ± 0.01% (measured as glycolic acid).

Keywords


bengkoang, vitamin A, vitamin C, alpha hydroxyl acid



References

American Cancer Society, 2014. Skin Cancer: Basal and Squamous Cell. (http://www.cancer.org, diakses pada 13 Maret 2015)

Carocho, M., and Ferreira, I.C.F.R. 2013. A Review on Antioxidants, Prooxidants and Related Controversy: Natural and Synthetic Compounds, Screening and Analysis Methodologies and FuturePerspectives. Food Chem.Toxicol. 51: 15–25.

Haynes, W.M. (ed.). 2013. Handbook of Chemistry and Physics. 94th ed. CRC Press LLC, Boca Raton: Florida. pp. 3-284

Juzeniene, A. and Moan, J. 2012. Beneficial Effects of UV Radiation Other Than Via Vitamin D Production, Dermatoendocrinol. 4(2): 109–117.

Khatib, S., Nerya, O., Musa, R., Shmuel, M., Tamir, S., Vaya, J. 2005. Chalcones as potent tyrosinase inhibitors: the importance of a 2,4-substituted resorcinol moiety. Bioorg. Med. Chem. 13: 433-441.

Kim, D., Park, J., Kim, J., Han, C., Yoon, J., Kim, N., Seo, J., Lee, C. 2006. Flavonoids as mushroom inhibitors: A Fluorescense quenching study. J. Agric. Food Chem. 54: 935-941

Lukitaningsih, E. 2009. The exploration of whitening and sun screening compounds in bengkoang roots (Pachyrhizus erosus), Dissertation, Würzburg, Germany

Lukitaningsih, E., Bahi, M., Holzgrabe, U. 2013. Tyrosinase Inhibition Type of Isolated Compounds Obtained from Pachyrhizus erosus. Aceh Int. J. Sci. Technol. 2 (3): 98-102.

Lukitaningsih, E., Holzgrabe, U. 2014. Bioactive compounds in Bengkoang (Pachyrhizus erosus) as Antioxidant and Tyrosinase Inhibition Agents. Indonesian J. Pharm. 25(2): 68-75.

Lukitaningsih, E. 2012. Phytosterol in Bengkoang. Pharmacon. 13(2): p 47-54. Matsuura, R., Ukeda, H., Sawamura, M. 2006. Tyrosinase inhibitory activity of Citrus essential oils. J. Agric. Food Chem. 54: 2309-2313.

Nurrochmad, A., Lukitaningsih, E., Monikawati, A., Septhea, D.B., Meiyanto, E. 2013. Combination of low-concentration of novel phytoestrogen (8,9)-furanyl-pterocarpan-3-ol from Pachyrhizus erosus attenuated tamoxifen-associated growth inhibition on breast cancer T47D cells. Asian Pac J Trop Biomed. 3(11): 847-852 .

Pouillot, A., Polla, L.L., Tacchini, P., Neequaye, A., Polla, A., dan Polla, B. 2011. Natural Antioxidants and Their Effects on The Skin. in: Formulating, Packaging, and Marketing of Natural Cosmetic Products. John Wiley & Sons, Inc., pp 239 – 253.

Sandler, J. A. 2005. The Phytochemical Extraction and analysis of new flavonoids and saponins from the genus Silphium, Dissertation, The University of Texas at Austin, pp 1-23.

Standring, S. 2008. Gray’s Anatomy : The Anatomical Basis of Clinical Practice, Churchill Livingstone, UK.

Sudjaroen, Y., Haubner, R., Würtele, G., Hull, W. E., Erben, G., Spiegelhalder, B., Changbumrung, S., Bartsch, H., Owen, R. W. 2005. Isolation and structure elucidation of phenolic antioxidants from Tamarind (Tamarindus indica L.) seeds and pericarp, Food Chem. Toxicol. 43: 1673-1682.

Walters, C., Keeney, A., Wigal, C.T., Johnston, C.R., and Cornelius, R. 1997. The spectrophotometric analysis and modelling of sunscreens. J. Chem. Edu. 74: 99-101.

Wang, K.H., Lin, R.D, Hsu, F.L., Huang, Y.H., Chang, H.C., Huang, C.Y., Lee, M.H. 2006. Cosmetic applications of elected traditional Chinese herbal medicines. J. Ethnopharmacol. 106: 353-359.



DOI: https://doi.org/10.22146/tradmedj.10726

Article Metrics

Abstract views : 7032 | views : 43193

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2016 Majalah Obat Tradisional

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

©Majalah Obat Tradisional (Traditional Medicine Journal)
 ISSN 2406-9086
Faculty of Pharmacy
Universitas Gadjah Mada