Formulation, Physical Quality Evaluation, and Antioxidant Activity of Body Butter of Ethanol Extract of Dragon Fruit (Hylocereus polyrhizus) Peel

https://doi.org/10.22146/mot.51763

Agustina Nila Yuliawati(1*), Kadek Duwi Cahyadi(2)

(1) Mahaganesha College of Pharmacy
(2) Mahaganesha College of Pharmacy
(*) Corresponding Author

Abstract


Dragon fruit (Hylocereus polyrhizus) has polyphenols as an antioxidant. It has known that the antioxidant content of dragon fruit peels was more than in the flesh, so it can be used as a source of natural antioxidants to replace synthetic antioxidants. The use of dragon fruit (Hylocereus polyrhizus) peel, especially as topical preparations in the form of body butter, was still rarely done, whereas dragon fruit peel as an antioxidant can be used as an active ingredient of cosmetics. The purpose of this study was to obtain the body butter formula of ethanol extract of dragon fruit (Hylocereus polyrhizus) peel and its physical quality evaluation, to know the antioxidant activity of ethanol extract of dragon fruit (Hylocereus polyrhizus) peel and its body butter. This research was an experimental study with the stages of research consisting of determination of native plants, making ethanol extract of dragon fruit (Hylocereus polyrhizus) peel, ensuring its activity antioxidant, performing body butter formulation procedures, carrying out physical quality evaluation such as organoleptic, homogeneity, pH, spread, protection, and adhesion ability, then antioxidant activity of its body butter. The result of this research showed that the ethanol extract of dragon fruit (Hylocereus polyrhizus) peel has a moderate level of antioxidant (Antioxidant Activity Index / AAI = 0,88). Furthermore, body butter which has contains antioxidant content of ethanol extract of dragon fruit (Hylocereus polyrhizus) peel as much as 0.5% has the best physical quality evaluation during storage and the highest AAI (0,54) among other body butter formulas.


Keywords


Hylocereus polyrhizus; body butter; formulation; physical evaluation; antioxidant

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References

Adnan, L., Osman, A. & Abdul Hamid, A., 2011. 'Antioxidant activity of different extracts of red pitaya (Hylocereus polyrhizus) seed', International Journal of Food Properties. 14, 1171–1181.

Arikumalasari, J., Dewantara, I.G.N.A. & Wijayanti, N.P.A.D., 2013. 'Optimasi HPMC sebagai gelling agent dalam formula gel ekstrak kulit buah manggis (Garcinia mangostana L.)', Jurnal Farmasi Udayana. 2 (3), 145-152.

Del-Toro-Sánchez, C.L., Gutiérrez-Lomelí, M., Lugo-Cervantes, E., Zurita, F., Robles-García, M.A., Ruiz-Cruz, S., Aguilar, J.A., Morales-Del Rio, J.A. & Guerrero-Medina, P.J., 2015. 'Storage effect on phenols and on the antioxidant activity of extracts from anemopsis californica and inhibition of elastase enzyme', Journal of Chemistry. 2015, 1–8.

Deuschle, V.C.K.N., Deuschle, R.A.N., Bortoluzzi, M.R. & Athayde, M.L., 2015. 'Physical chemistry evaluation of stability, spreadability, in vitro antioxidant, and photo-protective capacities of topical formulations containing Calendula officinalis L. leaf extract', Brazilian Journal of Pharmaceutical Sciences. 51, 63–75.

Hamzah, N., Ismail, I. & Saudi, A.D.A., 2014. 'Pengaruh emulgator terhadap aktivitas antioksidan krim ekstrak etanol kelopak bunga rosella (Hibiscus Sabdariffa Linn)', Jurnal Kesehatan. 7 (2), 376-386.

Indrayudha, P., Rahmawati, D. & Sukmawati, A., 2010. 'Formulasi krim minyak atsiri rimpang temu giring (Curcuma heyneana Val & Zijp): uji sifat fisik dan daya antijamur terhadap Candida Albicans secara in vitro'. Majalah Obat Tradisional. 15 (2), 56-63.

Jamilah, B., Shu, C.E., Kharidah, M., Dzulkifly, M.A., & Noranizan, 2011. 'Physico-chemical characteristics of red pitaya (Hylocereus polyrhizus) peel'. International Food Research Journal. 18, 279–286.

Jasti, B.R., Abraham, W. & Ghosh, T.K., 2004. 'Transdermal and topical delivery systems', in Ghosh, T.K., & Jasti, B.R., Theory and Practice of Contemporary Pharmaceutics, pp. 445-446, CRC Press, Boca Raton.

Juwita, A.P., Yamlean, P.V.Y. & Edy, H.J., 2013. 'Formulasi krim ekstrak etanol daun lamun (Syringodium isoetifolium)', PHARMACON Jurnal Ilmiah Farmasi – UNSRAT. 2 (2), 8-12.

Kedare, S.B. & Singh, R.P., 2011. 'Genesis and development of DPPH method of antioxidant assay', Journal of Food Science and Technology, 48, 412–422.

Kusumawati, I. & Indrayanto, G., 2013. 'Natural antioxidants in cosmetics', in: Studies in Natural Products Chemistry, Elsevier, pp. 485–505.

Lambers, H., Piessens, S., Bloem, A., Pronk, H. & Finkel, P., 2006. 'Natural skin surface pH is on average below 5, which is beneficial for its resident flora', International Journal of Cosmetic Science. 28, 359–370.

Le Bellec, F., Vaillant, F. & Imbert, E., 2006. 'Pitahaya ( Hylocereus spp.): a new fruit crop, a market with a future', Fruits. 61 (4), 237–250.

Manihuruk, F.M., Suryati, T. & Arief, I.I., 2017. 'Effectiveness of the red dragon fruit (Hylocereus polyrhizus) peel extract as the colorant, antioxidant, and antimicrobial on beef sausage', Media Peternakan. 40, 47–54.

Omidizadeh, A., Yusof, R.M., Ismail, A., Roohinejad, S., Nateghi, L. & Bakar, M.Z.A., 2011. 'Effects of different cooking and drying methods on antioxidant and dietary fiber properties of red pitaya (Hylocereus polyrhizus)', Advance Journal of Food Science and Technology. 3(3), 203-210.

Purwanto, Mufrod, & Swastika, A.N.S.P., 2013. 'Antioxidant activity of cream dosage form of tomato extract (Solanum lycopersicum L.)', Traditional Medicine Journal. 18(3), 132–140.

Rompis, F.F., Yamlean, P.V.Y. & Lolo, W.A., 2019. 'Formulasi dan uji efektivitas antioksidan sediaan masker peel-off ekstrak etanol daun sesewanua (Cleodendron Squamatum Vahl.)', PHARMACON Jurnal Ilmiah Farmasi – UNSRAT. 8 (2), 151-159.

Sayuti, N.A., 2017. 'Uji aktivitas antiaging in vitro lavender body butter', Jurnal Kebidanan dan Kesehatan Tradisional Politeknik Kesehatan Kemenkes Surakarta. 2 (1), 30-37.

Scherer, R. & Godoy, H.T., 2009. 'Antioxidant activity index (AAI) by the 2,2-diphenyl-1-picrylhydrazyl method', Food Chemistry. 112, 654–658.

Selvamuthukumaran, M. & Shi, J., 2017. 'Recent advances in extraction of antioxidants from

plant by-products processing industries', Food Quality and Safety, Oxford University Press on behalf of Zhejiang University Press. 1, 61–81.

Singh, S., Sarkar, B.K., Ramaiah, M., Devgan, M. & Chowdary, Y.A., 2015. 'Formulation, evaluation and stability study of herbal cream containing embelin', International Journal of Pharmacognosy. 2 (3), 136-138.

Suena, N.M.D.S., Antari, N.P.U. & Cahyaningsih, E., 2017. 'Evaluasi mutu fisik formula body butter ekstrak etanol kulit buah manggis (Garcinia mangostana L.), Jurnal Ilmu Kefarmasian Indonesia. 15 (1), 63–69.

Thorat, I.D, Jagtap, D.D., Mohapatra D., Joshi, D.C., Sutar, R.F., & Kapdi S.S. 2013. 'Antioxidants, their properties, uses in food products and their legal implications', International Journal of Food Studies. 2, 81–104.

Wahyuningtyas, S.E.P., Permana, I.G.D.M. & Wiadnyani, A.A.I.S. 2017. 'Pengaruh jenis pelarut terhadap kandungan senyawa kurkumin dan aktivitas antioksidan ekstrak kunyit (Curcuma domestica Val.)', Jurnal ITEPA. 6 (2), 61-70.

Wu, L., Hsu, H.-W., Chen, Y.-C., Chiu, C.-C., Lin, Y.-I. & Ho, J.A., 2006. 'Antioxidant and antiproliferative activities of red pitaya', Food Chemistry. 95, 319–327.

Xu, P., Chen, L. & Wang, Y., 2019. 'Effect of storage time on antioxidant activity and inhibition on α‐amylase and α‐glucosidase of white tea', Food Science & Nutrition. 7, 636–644.

Zain, N.M. & Nazeri, M.A., 2016. 'Antioxidant and mineral content of pitaya peel extract obtained using Microwave Assisted Extraction (MAE)', Australian Journal of Basic and Applied Sciences. 10 (17), 63-68.





DOI: https://doi.org/10.22146/mot.51763

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