Stability of Ethanol Extract Sunscreen Spray Gel Formula Kalakai Leaves (Stenochlaena palustris (Burm F.) Bedd)

Weni Puspita(1*), Heny Puspasari(2), Dian Kartikasari(3)
(1) Akademi Farmasi Yarsi Pontianak, East Pontianak, West Kalimantan
(2) Akademi Farmasi Yarsi Pontianak, East Pontianak, West Kalimantan
(3) Akademi Farmasi Yarsi Pontianak, East Pontianak, West Kalimantan
(*) Corresponding Author
Abstract
There is evidence that an ethanol extract from the leaves of the kalakai tree (Stenochlaena palustris (Burm F.) Bedd.) may provide ultra-protective sun protection. The purpose of this study is to analyze the stability of a sunscreen spray gel composition that contains an ethanol extract of kalakai leaves. We used a rotary evaporator to concentrate the kalakai leaf ethanol extract until it was thick, after macerating the leaves in 70% ethanol solvent. A spray gel formulation containing EEKL was subsequently created, with EEKL concentrations of 5% (FI), 7.5% (FII), and 10% (FIII). The physical stability of the EEKL Spray gel formula was examined by six cycles of the cycling test technique in a climatic chamber with temperatures of 40°C ± 2°C and 4°C ± 2°C. Organoleptics, consistency, thickness, pH, adhesive spreading ability, and spray pattern are some of the tests that are conducted. Using a UV-Vis spectrophotometer set at 290-320 nm wavelength, the sunscreen test was conducted. A t-dependent test was used to examine the quantitative data on physical stability and sunscreen. No significant variations were seen throughout six storage cycles (p>0.05), indicating high physical stability, for the three EEKL Spray gel compositions (FI:5%, FII:7.5%, FIII: 10%). Formula III, which falls under the ultra protection category and had the highest average SPF value before and after the cycling test at 35.82 ± 0.50, exhibited no significant change (P>0.05) in the sunscreen activity during the six storage cycles, according to the results of the stability test of the EEKL Spray gel sunscreen activity in the three formulas.
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Faculty of Pharmacy
Universitas Gadjah Mada