Skrining Talasemia Beta Minor pada Pelajar SMK di Kecamatan Ciamis

Doni Setiawan; Atun Farihatun; Ary Nurmalasari

doi:10.22146/jkesvo.57621

Skrining Talasemia Beta Minor pada Pelajar SMK di Kecamatan Ciamis

https://doi.org/10.22146/jkesvo.57621

Doni Setiawan^(1*), Atun Farihatun⁽²⁾, Ary Nurmalasari⁽³⁾

(1) Program Studi Teknologi Laboratorium Medik, Sekolah Tinggi Ilmu Kesehatan Muhammadiyah, Ciamis, Jawa Barat
(2) Program Studi Teknologi Laboratorium Medik, Sekolah Tinggi Ilmu Kesehatan Muhammadiyah, Ciamis, Jawa Barat
(3) Program Studi Teknologi Laboratorium Medik, Sekolah Tinggi Ilmu Kesehatan Muhammadiyah, Ciamis, Jawa Barat
(*) Corresponding Author

Abstract

Latar Belakang: Frekuensi talasemia beta minor di Indonesia mencapai 6–10%. Talasemia beta minor bersifat asimtomatik sehingga peran deteksi dini perlu dilakukan untuk mencegah kelahiran talasemia mayor. Pemeriksaan hematologi telah diketahui dan teruji dapat digunakan untuk skrining talasemia beta minor pada populasi beresiko. Meningkatnya penderita talasemia beta mayor di Kabupaten Ciamis dikarenakan belum maksimalnya skrining dilakukan.
Tujuan: Mengetahui frekuensi talasemia beta minor pada pelajar SMK di Kecamatan Ciamis.
Metode: Penelitian ini menggunakan metode deskriptif kuantitatif, dengan teknik cross‑sectional, yang telah dilakukan sejak bulan Maret‑Juni 2020. Subjek penelitian adalah pelajar SMK di Kecamatan Ciamis. Parameter pemeriksaan yang digunakan untuk skrining talasemia beta minor adalah MCV, Indeks Men3er, Indeks RDW, dan OTOFT.
Hasil: Dari seluruh pelajar yang mengisi kuesioner sebanyak 238 pelajar, hanya 60 pelajar yang bersedia dan memenuhi kriteria penelitian. Hasil pemeriksaan parameter skrining talasemia beta minor didapatkan 5 (8,3%) pelajar MCV < 80 fL, 3 (5%) pelajar Indeks Men8er <13, Indeks RDW < 220 6 (10%) pelajar dan 9 (15%) pelajar dengan OTOFT positif.
Kesimpulan: Pada penelitian ini ditemukan 3 (5%) pelajar sebagai talasemia beta minor.

Keywords

talasemia; skrining pembawa sifat; pemeriksaan hematologi; indeks eritrosit

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DOI: https://doi.org/10.22146/jkesvo.57621