Evaluation of Students’ Skills in Compounding of Divided Powders


M Rifqi Rokhman(1*), Hardika Aditama(2), Angi Nadya Bestari(3)

(1) Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(2) Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(3) Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(*) Corresponding Author


Several types of medicines for pediatric patients are not commercially available in appropriate dosage forms. While divided powder resulted from compounding process is an alternative to address this problem, the dosage accuracy is still profoundly a major issue. This research was aimed at comparing student’s ability prior to and after taking compounding practical work and analyzing weight accuracy of divided powders compounded by students. This research was designed as a pre-post study. Students who were taking compounding practical work (for 12 weeks) in 2017 were asked to fill a prescription contained divided powders in the beginning and the end of the semester, given enriched learning material of compounding technique videos and feedback as evaluation of their pretest results. The data is presented in the form of a percentage, while differences between pretest and post-test are compared utilizing Wilcoxon test. This study suggests that there was a significant increase of students’ ability in calculating the amount of each ingredient required to fill the prescription, choice of label color, approximating the beyond-use date, folding the divided powders, and making a copy of the prescription. However, there was a small number of students (15.3%) whose divided powders they have dispensed were in the allowed weight range. This study documents the need for quality assessment of medications prepared by students quantitatively and this assessment serves as a parameter of student performance.


compounding; penilaian mahasiswa; pulveres; keseragaman bobot; student assessment; divided powders; weight uniformity

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1. Park HL, Shrewsbury RP. Student Evaluation of Online Pharmaceutical Compounding Videos. Am J Pharm Educ. 2016;80(2):1-7.

2. Roark AM, Anksorus HN, Shrewsbury RP. Long-term Results of an Analytical Assessment of Student Compounded Preparations. Am J Pharm Educ. 2014;78(9):1-6.

3. Indonesian Pharmacist Association. Indonesian Pharmacist Competency Standards. Jakarta: IAI; 2016.

4. Kristina SA, Wiedyaningsih C, Widyakusuma NN, Aditama H. Extemporaneous Compounding Practice By Pharmacists : a Systematic Review. Int J Pharm Pharm Sci. 2017;9(2):42-46.

5. Nahata MC, Allen L V. Extemporaneous Drug Formulations. Clin Ther. 2008;30(11):2112-2119.

6. Kolling WM, Mcpherson TB. Assessment of the Accuracy of Pharmacy Students ’ Compounded Solutions Using Vapor Pressure Osmometry. Am J Pharm Educ. 2013;77(3):1-5.

7. Capehart KD. A Laboratory Exercise in Capsule Making. Am J Pharm Educ. 2008;72(5).

8. Kadi A, Francioni-Proffitt D, Hindle M, Soine W. Evaluation of Basic Compounding Skills of Pharmacy Students. Am J Pharm Pharm Educ. 2005;69(4):508-515.

9. Shrewsbury RP, Deloatch KH. Accuracy in Prescriptions Compounded by Pharmacy Students. Int J Pharm Compd. 1998;2(2):139-142.

10. Marriot JF, Wilson KA, Langley CA, Belcher D. Pharmaceutical Compounding and Dispensing. Second Edi. London: Pharmaceutical Press; 2010.

11. Ministry of Health Decree. Ministry of Health Decree No 73 Year 2016 on Standards of Pharmaceutical Services in Pharmacy. Jakarta; 2016.

12. U.S.Pharmacopeial Convention. Pharmaceutical Compounding - Nonsterile Preparations. USPharmacopeia. 2014:356-360. http://www.usp.org/usp-nf/official-text/revision-bulletins/pharmaceutical-compounding-nonsterile-preparations.

13. Government Regulation. Government Regulation No 51 Year 2009 on Pharmaceutical Works. Jakarta: Pemerintah Republik Indonesia; 2009.

14. Sugianto L, Yetti O, Handayani S. Uji Keseragaman Bobot dan Keseragaman Kadar Sediaan Pulveres yang Dibuat Apotek. J Heal Sci. 2008;3(6):1-5.

15. Wiedyaningsih C, Kristina SA, Widyakusuma NN, Aditama H. Opinion and Expectation of Pharmacists on Providing Extemporaneous Compounding in Jogjakarta and Central Java Provinces, Indonesia. Int J Pharm Pharm Sci. 2017;9(7):79-82. doi:10.22159/ijpps.2017v9i7.18358

16. Pignato A, Candidate P, Birnie CR. Analysis of Compounded Pharmaceutical Products to Teach the Importance of Quality in an Applied Pharmaceutics Laboratory Course. Am J Pharm Educ. 2014;78(3):1-10.

17. Mcgill JE, Holly DR. Integration of Pharmacy Practice and Pharmaceutical Analysis : Quality Assessment of Laboratory Performance. Am J Pharm Educ. 1996;60:370-374.

18. Begley K, Monaghan MS, Qi Y. Repeated Testing to Improve Skills in a Pharmacy Practice Laboratory Course. Am J Pharm Educ. 2013;77(6).

19. Morecroft CW. Engaging in Reflection: Error Logs and The Developing Students’ Skills. Pharm Educ. 2011;11(1):172-176.

DOI: https://doi.org/10.22146/jmpf.42802

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