Pengaruh fasciolosis pada sapi bali berdasarkan pemeriksaan darah, serum glutamic pyruvic transaminase (SGPT), dan alkaline phosphatase (ALP)

Amirullah Amirullah; Dradjat AS; Sriasih M; Maskur Maskur; Depamede SN; Kisworo D; Kurniasih Kurniasih

doi:10.22146/jsv.42994

Pengaruh fasciolosis pada sapi bali berdasarkan pemeriksaan darah, serum glutamic pyruvic transaminase (SGPT), dan alkaline phosphatase (ALP)

https://doi.org/10.22146/jsv.42994

Amirullah Amirullah^(1*), Dradjat AS⁽²⁾, Sriasih M⁽³⁾, Maskur Maskur⁽⁴⁾, Depamede SN⁽⁵⁾, Kisworo D⁽⁶⁾, Kurniasih Kurniasih⁽⁷⁾

(1) Balai Karantina Pertanian Kelas I Mataram NTB
(2) Fakultas Peternakan Universitas Mataram
(3) Fakultas Peternakan Universitas Mataram
(4) Fakultas Peternakan Universitas Mataram
(5) Fakultas Peternakan Universitas Mataram
(6) Fakultas Peternakan Universitas Mataram
(7) Fakultas Kedokteran Hewan, Universitas Gadjah Mada
(*) Corresponding Author

Abstract

Investation of Fasciola sp. On several species of cattle in Indonesia has occurred since a long time ago. Fasciolosis caused a high economical loss such as decreasing of carcass and organs, sometimes caused death of calves. The objectives of the research were to evaluate the effect of fasciolosis on Serum Glutamic Pyruvic Transaminase (SGPT), and the obstruction of bile duct by Alkaline Phosphatase (ALP) in Bali cattle suffered from fasciolosis. Faeces of Bali cattle raised in endemic areas of fasciolosis were examinated by sedimentation test to identify eggs per gram of faeces (EPG) of Fasciola sp. The blood samples of cattle which positive to fasciolosis were use to study the hematology by autoanalyser, SGPT and ALP. The results of research showed that from 89 cattle, 28 were infected by Fasciola sp. whithin of 7-115 EPG (min-max). From 20 fasciolosis cattle were indicated that MCHC of 90%, RBC of 30%, HB of 20%, and eosinophils of 2 % of cattle were lower than that of normal standard, while lymphocytes of 60%, MCV of 40%, ALP of 10% and SGPT of 5% of cattle were higher than that of normal standard. hematological appearances of cattle suffered from fasciolosis had macrocytichypochromic anemia, eosinopenia, and lymphocytosis. The increase of SGPT may be caused byhepatic cells destruction by young liver flukes, and the increase of ALP was caused by the obstruction of bile duct by mature liver flukes.

Keywords

Cattle; Fasciolosis; Hematology; SGPT; ALP

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References

Adama, J.Y., O.J. Ajanusi, N. Chiezey, A.Lawal. 2011. Biochemical responses of yankasa sheep to experimental fasciola gigantica infection in Zaria, Nigeria. Int. J. anim. veter. adv., 3(6): 409-415.

Aghaei, S., A. Farahnak, T. Golmohammadi, M. Eshraghian, M. Molaeirad. 2017. In Vitro Assay Of Alkaline Phosphatase Enzyme Activity In Fasciola Infected Livers and Fasciola Hepatica Parasite. Journal of Paramedical Sciences, 8 (3): 13-17

Astiti, L.G.S and T. Panjaitan.2012. Mapping Of Fascioliasis On Bali Cattle In Lombok,International Conference on Livestock Production and Veterinary Technology: 416-42.

Chauvin, A., G. Bouvet, C. Boulard. 1995. Humoral And Cellular Immune Responses To Fasciola Hepatica Experimental Primary And Secondary Infection In Sheep.Int J Parasitol. 25(10):1227-41.

Cyntia, M.K., S. Line, S.E. Aiello. 2010. Merck Veterinay Manual, 10thed. 3239 Satellite Blvd., Duluth, Ga 30096.

Dharmayudha, A.A.G.O.,I.B.D Kusumadarma, I.B.K.Ardana,M.S. Anthara, I.W.N.F. Gunawan, L.M. Sudimartini, K.K. Agustina. 2018.Aktivitas Alanin Aminotransferase dan Aspartat Aminotransferase Sapi Bali Terinfeksi Fasciola Gigantica.Bulvet. vol 10 (1):87-92.http://ojs.unud.ac.id/index.php/buletinvet.

Edith, R., R. Godara, R.L. Sharma, M.B. Thilagar.2010. Serum Enzyme And Hematological Profile Of Fasciola gigantica Immunized And Experimentally Infected Riverine Buffaloes. Parasitol. Res.106, (4): 947–956.

Egbu,M.I.Florence., O.P. Ubachukwu, C.I. Okoye. 2013.Haematological Changes Due to Bovine Fascioliasis. Afr. J. Biotechnol., 12 (15):1828-1835.

Fraser, A., M. Longnecker, D. Lawlor. 2007. Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999–2004. Gastroenterology. 133: 1814–1820.

Ganguly,A., R.S. Bisla, S.S. Chaudhri. 2016. Haematological And Biochemical Change In Ovine Fasciolosis. Haryana vet, 55: 27-30.

George, J.W., J. Snipes, V.M. Lane. 2010. Comparison Of Bovine Hematology Reference Intervals From 1957 to 2006. Vet Clin Pathol 39: 138-148.

Hambal, M., S. Arman, D. Agus. 2013. Tingkat Kerentanan Fasciola gigantica pada Sapi dan Kerbau di Kecamatan Lhoong, Kabupaten Aceh Besar.JMV,7: 49-53

Hodzic, A., A. Zuko, R. Avdic, R. Alic, J. Omeragic, A. Jazic. 2013. Influence Of Fasciola Hepatica On Serum Biochemical Parameters And Vasculer Biliary System Of Sheep Liver. Iranian J. Parasitol. 8: 92-98.

Lotfollahzadeh, S., M. Mohri, ShR. Bahadori, M.R. Dezfouly, P. Tajik. 2008.The Relationship Between Normocytic, Hypochromic Anaemia And Iron Concentration Together With Hepatic Enzyme Activities In Cattle Infected With Fasciola Hepatica.J. Helminthol. (1) :85-88.

Macer, V.J. 2003. Veterinary Clinical Laboratory Tecniques. VET 24.

Martindah, E., S. Widjajanti, S.E. Estuningsih, Suhardono. 2005. Meningkatkan kesadaran dan kepedulian masyarakat terhadap fasiolosis sebagai penyakit zoonosis. Wartazoa 15: 143-154.

Munadi.2011, Tingkat Infeksi Cacing Hati Kaitannya Dengan Kerugian Ekonomi Sapi Potong yang Disembelih di Rumah Potong Hewan Wilayah Eks-Kresidenan Banyumas Agripet 11 (1): 45-50.

Pfukenyi, D.M., S. Mukaratirwa, Lii. Willingham, A.L.S. Monrad.2006. Epidemiological Studies of Fascila gigantica Infections In Cattle In The Highveld And Lowveld Communal Grazing Areas Of Zimbabwe. Onderstepoort J Vet Res.73(1), 37-51.

Shichibi.T.H. 2017. Study on the Prevalence and Economic Importance of Bovine Fasciolosis in Mizan Teferi Municipal Abattoir.World Applied Sciences Journal35 (2): 182-187, 2017.

Suchit, S. P., J. J. Hasnani, P. V. Patel, C. J. Dave, R. Shukla, N. D. Hirani. 2015. Study on Haemato-Biochemical Alterations Occurred in Fasciola spp. Infected. International Journal of Multidisciplinary Research and Development 2015; 2(3): 756-759.

Taylor, M. A., R. L. Coop, R. L. Wall. 2016. Veterinary Parasitology. 4th Edition UK: Blackwell Publishing.

Usib, L.P. E., E. S. Ibanga, H. J. Edoho, E. E. Amadi, E.Utah. 2014. Prevalence of Fascioliasis and the economic loss of condemned liver due to Fasciola infection in Cattle slaughtered at three abattoirs in Eket Urban, Akwa Ibom State of Nigeria. Global Advanced Research JFST, 3(2): 54-75.

Wiedosari. E., H. Hayakawa, B. Copeman. 2006. Host differences in response to trickle infection with Fasciola gigantica in buffalo, Ongole and Bali calves. Trop. Anim. Health Prod. 38:43-53.

WHO. 2007. World Health Organisation. Report of the WHO Informal Meeting on use of triclabendazole in fascioliasis controls. WHO/CDS/PCT/2007.

Whitlock, J. 2017.Liver Enzymes and Liver Function Tests and Results. The American Association of Clinical Chemistry.http://www.labtestsonline.org/understanding/analytes/liver_panel/glance.html.

Zhang,W.Y., M. Moreau,B.Z. Yang, Z. Q.Li, J.C. C. Hope, J. Howard, Y. W.Huang.2006. Humoral And Cellular Immune Responses To Fasciola Gigantica Experimental Infection In Buffaloes. Research In Vet. Sc80: 299-307.

DOI: https://doi.org/10.22146/jsv.42994