Pola Pemberian Nutrisi Parenteral Pada Neonatus di RSUPN dr. Cipto Mangunkusumo. Indonesia

https://doi.org/10.22146/farmaseutik.v20i2.75586

Hartati Mahmuda(1), Fita Rahmawati(2*), Rina Mutiara(3)

(1) Universitas Gadjah Mada
(2) Universitas Gadjah Mada
(3) RSUPN dr. Cipto Mangunkusumo
(*) Corresponding Author

Abstract


Neonatus merupakan pengguna terapi nutrisi parenteral paling banyak karena sebagian besar bayi prematur dan bayi lahir dengan berat sangat rendah akan membutuhkan terapi dukungan nutrisi sesegera mungkin setelah lahir. Pemberian nutrisi parenteral pada neonatus dapat mempengaruhi pertumbuhan pasca-kelahiran, meningkatkan perkembangan saraf, dan mengurangi risiko kematian. Penelitian ini bertujuan untuk mengetahui pola pemberian nutrisi parenteral yang diberikan pada neonatus diawal kelahiran. Penelitian ini menggunakan desain observational cross sectional. Penelusuran riwayat pemberian nutrisi parenteral pada neonatus dilakukan secara retrospektif melalui rekam medik dan sistem informasi manajemen rumah sakit. Sejumlah 118 neonatus memenuhi kriteria inklusi penelitian dengan kriteria berat badan ≤ 2.500 g, mendapatkan nutrisi parenteral di bangsal perinatologi, RSUPN dr. Cipto Mangunkusumo Jakarta. Informasi jenis nutrisi parenteral yang diberikan kepada neonatus pada hari pertama kelahiran dianalisis secara deskriptif. Hasil penelitian menunjukkan jenis nutrisi parenteral yang diberikan meliputi makronutrisi berupa glukosa, protein, dan lipid serta mikronutrisi multivitamin, kalsium, dan fosfat. Sejumlah 35 neonatus mendapatkan nutrisi protein-glukosa dengan atau tanpa mikronutrisi, 23 neonatus dengan nutrisi protein-glukosa-lipid dengan atau tanpa mikronutrisi sejumlah 60 neuonatus dengan nutrisi glukosa dengan atau tanpa mikronutrisi.  Nutrisi parenteral yang diberikan beragam sesuai kebutuhan masing-masing neonatus agar tidak terjadi malnutrisi. 


Keywords


berat badan, neonatus, nutrisi parenteral, perinatologi.

Full Text:

PDF


References

Abubakari, A., Kynast-Wolf, G., dan Jahn, A., 2015. Prevalence of abnormal birth weight and related factors in Northern region, Ghana. BMC Pregnancy and Childbirth, 15: 335.

Al-lawama, M., Abu Alrous, H., Alkhatib, H., Alrafaeh, A., Wakileh, Z., Alawaisheh, B., dkk., 2019a. Nutritional Support of Very Low Birth Weight Infants in a Tertiary Center in a Developing Country. Journal of Clinical Medicine Research, 11: 283–288.

Al-lawama, M., Abu Alrous, H., Alkhatib, H., Alrafaeh, A., Wakileh, Z., Alawaisheh, B., dkk., 2019b. Nutritional Support of Very Low Birth Weight Infants in a Tertiary Center in a Developing Country. Journal of Clinical Medicine Research, 11: 283–288.

Bost, R.B., Tjan, D.H., dan van Zanten, A.R., 2014. Timing of (supplemental) parenteral nutrition in critically ill patients: a systematic review. Annals of Intensive Care, 4: 31.

Bronsky, J., Campoy, C., Braegger, C., Braegger, Christian, Bronsky, Jiri, Cai, W., dkk., 2018. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Vitamins. Clinical Nutrition, 37: 2366–2378.

Jochum, F., Moltu, S.J., Senterre, T., Nomayo, A., Goulet, O., Iacobelli, S., dkk., 2018. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Fluid and electrolytes. Clinical Nutrition, 37: 2344–2353.

Joosten, K., Embleton, N., Yan, W., Senterre, T., Braegger, C., Bronsky, J., dkk., 2018. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Energy. Clinical Nutrition, 37: 2309–2314.

Lapillonne, A., Fidler Mis, N., Goulet, O., van den Akker, C.H.P., Wu, J., Koletzko, B., dkk., 2018. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Lipids. Clinical Nutrition, 37: 2324–2336.

Lee, M.-S., Huang, Y.-C., Lee, C.-H., Chen, H.-N., Hsiao, C.-C., dan Huang, S.-C., 2020. Implementation of nutrition practice improves growth velocity and weight gain in premature infants ≤ 1250 grams. Pediatrics & Neonatology, 61: 534–541.

Lemeshow, S. dan World Health Organization (Editor), 1990. Adequacy of Sample Size in Health Studies. Published on behalf of the World Health Organization by Wiley ; Distributed in the U.S.A., Canada, and Japan by Liss, Chichester [England] ; New York : New York, NY, USA.

Mahovo, R. dan Velaphi, S., 2020. Duration of Hospital Stay and Factors Associated with Prolonged Hospital Stay in Very Low Birth Weight Infants Surviving to Hospital Discharge. Journal of Pediatrics, Perinatology and Child Health, 03: .

Mesotten, D., Joosten, K., van Kempen, A., Verbruggen, S., Braegger, C., Bronsky, J., dkk., 2018. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Carbohydrates. Clinical Nutrition, 37: 2337–2343.

Mihatsch, W., Fewtrell, M., Goulet, O., Molgaard, C., Picaud, J.-C., Senterre, T., dkk., 2018. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Calcium, phosphorus and magnesium. Clinical Nutrition, 37: 2360–2365.

Morisaki, N., Belfort, M.B., McCormick, M.C., Mori, R., Noma, H., Kusuda, S., dkk., 2014. Brief Parenteral Nutrition Accelerates Weight Gain, Head Growth Even in Healthy VLBWs. PLoS ONE, 9: e88392.

Patel, P. dan Bhatia, J., 2017. Total parenteral nutrition for the very low birth weight infant. Seminars in Fetal and Neonatal Medicine, 22: 2–7.

Ragab, M.H., Al-Hindi, M.Y., dan Alrayees, M.M., 2016. Neonatal parenteral nutrition: Review of the pharmacist role as a prescriber. Saudi Pharmaceutical Journal, 24: 429–440.

Oktavia, Y.S., Arifin, H., dan Yosmar, R., 2017. Parenteral Nutrition In Neonatus And Compatibility Issues: A Review Article. Asian Journal of Pharmaceutical and Clinical Research, 10: 54.

Stawny, M., Olijarczyk, R., Jaroszkiewicz, E., dan Jelińska, A., 2013. Pharmaceutical Point of View on Parenteral Nutrition. The Scientific World Journal, 2013: 1–9.

Turpin, R.S., Liu, F.X., Prinz, M., Macahilig, C., dan Malinoski, F., 2013. Parenteral Nutrition Prescribing Pattern: A Medical Chart Review of 191 Preterm Infants. Nutrition in Clinical Practice, 5.



DOI: https://doi.org/10.22146/farmaseutik.v20i2.75586

Article Metrics

Abstract views : 827 | views : 1179

Refbacks

  • There are currently no refbacks.


Majalah Farmaseutik Indexed by:

   
 
Creative Commons Licence
 
 
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.