Perioperative Fetal Surgery

  • Yusuf Raksawardana Faculty of Medicine, Public Health, and Nursing, Gadjah Mada University, Yogyakarta
Keywords: Fetal surgery, Open surgery, perioperative

Abstract

Anesthetic risk is inversely proportional to age, with neonates having a higher risk of mortality and morbidity compared to adults. Understanding these differences is essential for appropriate perioperative evaluation, preparation, planning, and anesthetic management in neonatal and fetal surgery. Advances in prenatal diagnostic techniques have improved the accuracy of fetal anomaly detection, enabling timely surgical intervention when indicated. Fetal surgery includes minimally invasive procedures, open fetal surgery, and ex utero intrapartum treatment (EXIT) procedures. Surgical intervention is considered when congenital abnormalities threaten fetal survival or lead to severe postnatal morbidity.

References

Andropoulos DB, Anesthesia for fetal intervention and surgery, in Gregory’s Pediatric Anesthesia. 6th Ed. Hoboken. 2020, 475–500.

Chestnut DH, Nathan N, Anesthesia for fetal surgery and other intrauterine procedures, in Chestnut’s Obstetric Anesthesia: Principles and Practice. 6th Ed. Philadelphia. 2020, 134–49.

Cohen DE, Kurth CD, Anesthesia for fetal surgery, in Smith’s Anesthesia for Infants and Children. 9th Ed. St. Louis. 2017, 589–604.

Apfelbaum JL, Hawkins JL, Agarkar M, Bucklin BA, Connis RT, Gambling DR, et al. Practice guidelines for obstetric anesthesia. Anesthesiology. 2016;124(2):270–300. https://journals.lww.com/anesthesiology/fulltext/2016/02000/practice_guidelines_for_obstetric_anesthesia__an.14.aspx

Zamora IJ, Ethun CG, Evans LM, Olutoye OO, Ivey RT, Haeri S, et al. Maternal morbidity and reproductive outcomes related to fetal surgery. J Pediatr Surg. 2013;48(5):951–55. https://www.jpedsurg.org/article/S0022-3468(13)00100-0/abstract

Al-Refai A, Ryan G, Van Mieghem T. Maternal risks of fetal therapy. Curr Opin Obstet Gynecol. 2017;29(2):80–4.

Graves CE, Harrison MR, Padilla BE. Minimally invasive fetal surgery. Clin Perinatol. 2017;44(4):729–51.

Strümper D, Gogarten W, Marcus AE. Anaesthesia for fetal surgeries. Indian J Anaesth. 2009;53(5):554–62.

Brusseau R, Mizrahi-Arnaud A. Fetal anesthesia and pain management for intrauterine therapy. Clin Perinatol. 2013;40(3):429–42.

Tran KM, Maxwell LG, Cohen DE, Adamson PC, Moll V, Kurth CD, et al. Quantification of serum fentanyl concentrations during ex utero intrapartum therapy. Anesth Analg. 2012;114(6):1265–1271.3w

Published
2026-01-13
How to Cite
Raksawardana, Y. (2026). Perioperative Fetal Surgery. Jurnal Komplikasi Anestesi, 12(3), 175-77. https://doi.org/10.22146/jka.v12i3.27659
Section
Literature Review