* Corresponding Author
Synthesis of Fe3O4/Hydroxyapatite Nanocomposites: Structural, Surface, and Magnetic Characterization
https://doi.org/10.22146/ijc.107697 Ahmad Fadli(1), Agung Prabowo(2*), Drastinawati Drastinawati(3), Bima Wandika Putra(4), Heni Sugesti(5), Febriyati Puspasari(6)
(1) Department of Chemical Engineering, Faculty of Engineering, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km. 12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(2) Department of Chemical Engineering, Politeknik Negeri Samarinda, Jl. Dr. Cipto Mangunkusumo, Samarinda 75131, Indonesia
(3) Department of Chemical Engineering, Faculty of Engineering, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km. 12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(4) Department of Chemical Engineering, Faculty of Engineering, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km. 12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(5) Department of Chemical Engineering, Politeknik Negeri Sriwijaya, Jl. Srijaya Negara Bukit Besar, Palembang 30139, Indonesia
(6) Department of Chemical Engineering, Politeknik Negeri Samarinda, Jl. Dr. Cipto Mangunkusumo, Samarinda 75131, Indonesia
(*) Corresponding Author
Abstract
Magnetite/hydroxyapatite (Fe3O4/HA) nanocomposites are promising materials for biomedical applications, particularly in targeted drug delivery. This study investigates the effects of hydrothermal reaction time and FeCl3 precursor concentration on the structural, morphological, and magnetic properties of Fe3O4/HA composite powders synthesized via a one-pot hydrothermal method. The resulting composites exhibit biphasic structures comprising magnetite (cubic phase) and hydroxyapatite (hexagonal phase) crystallites, with average sizes ranging from 22 to 30 nm. Both increased reaction time and FeCl3 concentration contributed to the growth of crystal size. A notable enhancement in specific surface area was observed, increasing from 48.21 to 67.41 m2/g as FeCl3 concentration decreased from 0.15 to 0.05 M at a fixed reaction time of 15 h. Magnetic characterization revealed that the composites exhibited superparamagnetic behavior, with the highest saturation magnetization (Ms) reaching 17.27 emu/g. These results demonstrate that tuning synthesis parameters can optimize the structural and magnetic properties of Fe3O4/HA nanocomposites, making them strong candidates for use in controlled drug delivery systems.
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DOI: https://doi.org/10.22146/ijc.107697
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