SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF THIAZOLE DERIVATIVES CONTAINING TRIAZOLE MOIETY USING LiBr AS A CATALYST

https://doi.org/10.22146/ijc.21446

Chetna Ameta(1), Diwaker Sitha(2), Rajat Ameta(3), Suresh C. Ameta(4*)

(1) Synthesis Laboratory, Department of Chemistry, M. L. Sukhadia University, Udaipur (Raj.)- 313 001
(2) Synthesis Laboratory, Department of Chemistry, M. L. Sukhadia University, Udaipur (Raj.)- 313 001
(3) Cadila Zyfine, Ahmedabad (Guj.)
(4) Synthesis Laboratory, Department of Chemistry, M. L. Sukhadia University, Udaipur (Raj.)- 313 001
(*) Corresponding Author

Abstract


Synthesis of triazole derivatives from 2-mercaptobenzothiazole has been achieved in four steps under microwave irradiation. LiBr potentially replace solvents and corrosive acids in this reaction scheme. The products of triazole derivatives have shown antimicrobial activity.

Keywords


LiBr; Microwave irradiation; Solvent free condition; Basic alumina

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References

[1] Sheldon, R.A., 2005, Green Chem., 7, 267–278.

[2] Kobayashi, S., and Manabe, K., 2002, Acc. Chem. Res., 35, 4, 209–217.

[3] Li, C.J., 2005, Chem. Rev., 105, 8, 3095–3166.

[4] Kappe, C.O., 2004, Angew. Chem. Int. Ed., 43, 46, 6250–6284.

[5] Delmas, F., Giorgio, C.D., Robin, M., Azas, N., Gasque, M., Detang, C., Costa, M., Pierre, T.D., and Galy, J-P., 2002, Antimicrob. Agents Chemother., 46, 8, 2588–2594.

[6] Hamday, M., Rahman, A., and Mohamed, A.L., 2007, J. Enzyme Inhib. Med. Chem., 22, 1, 57–64.

[7] Buffa, R., Zahradnik, P., and Flotinova, P., 2002, Collect. Czech. Chem. Commun., 67, 12, 1820–1832.

[8] Franchini, C., Muraglia, M., Corbo, F., Florio, M.A., Di Mola, A., Rosato, A., Matucchi, R., Nesi, M., Van, B.F., and Vitali, C., 2009, Arch. Pharm., 342, 605–613.

[9] Tatsumi, Y., Yokoo, M., Arika, T., and Yamaguchi, H., 2001, Antimicrob. Agents Chemother., 45, 5, 1493–1499.

[10] Lui, J., Li, L., Dai, H., Lui, Z., and Fang, J., 2006, J. Organomet. Chem., 691, 12, 2686–2690.

[11] Maesaki, S., Iwakawa, J., Higashiyama, Y., Miyazaki, Y., Yanagihara, K., Tomno, K., Tashiro, T., and Kohno, S., 2000, J. Infect. Chemother., 6, 101–103.

[12] Banfi, E., Scialino, G., Zampieri, D., Mamolo, M.G., Vio, L., Ferrone, M., Fermeglia, M., Paneni, M.S., and Pricl, S., 2006, J. Antimicrob. Chemother., 58, 1, 76–84.

[13] Ei-Sayed, R., 2006, Grasas y Aceties, 57, 2, 180–188.

[14] Havaldar, F.H., and Patil, A.R., 2008, Eur. J. Chem., 5, 2, 347–354.

[15] Singh, R.S., and Singh, D.K., 2010, E-J. Chem., 7, 37–40.

[16] Wang, H-L., Liu, R-B., and Jian, X., 2004, Corros. Sci., 46, 2455–2466.

[17] Abd Allah, O.A., 2000, Farmaco, 55, 9-10, 641–649.

[18] De Almeida, M.V., Cardoso, S.H., De Assis, J.V., and De Souza, M.V.N., 2007, J. Sulfur Chem., 28, 17–22.

[19] Chakraborti, A.K., Rudrawar, S., and Kondaskar, A., 2004, Eur. J. Org. Chem., 17, 3597–3600.

[20] Bandgar, B.P., Uppalla, L.S., and Sadavarte, V.S., 2002, J. Chem. Res., 1, 40–41.

[21] Maiti, G., Kundu, P., and Guin, C., 2003, Tetrahedron Lett., 44, 13, 2757–2758.

[22] Aroua, L., and Baklouti, A., 2007, Synth. Commun., 37, 1935–1942.

[23] Gregg, B.T., Golden, K.C., Quinn, J.F., Tymoshenco, D.O., Earlet, W.G., Razzano, D.A., Rennells, W.M., and Butcher, J., 2007, J. Comb. Chem., 9, 1036–1040.

[24] Pasha, M.A., Mahammed, K.A., and Jayashankara, V.P., 2007, Synth. Commun., 37, 4319–4326.



DOI: https://doi.org/10.22146/ijc.21446

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