Isolation and Antioxidant and Antibacterial Activity of Flavonoid from Ficus variegate Blume

https://doi.org/10.22146/ijc.23947

Rolan Rusli(1*), Bela Apriliana Ningsih(2), Agung Rahmadani(3), Lizma Febrina(4), Vina Maulidya(5), Jaka Fadraersada(6)

(1) Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan
(2) Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan
(3) Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan
(4) Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan
(5) Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan
(6) Faculty of Pharmacy, University of Mulawarman, Samarinda, East Kalimantan
(*) Corresponding Author

Abstract


Ficus variegata Blume is specific plant of east Kalimantan. Flavonoid compound of Ficus variegata Blume was isolated by vacuum liquid and column chromatography, with previously extracted by maceration method using n-hexane and methanol, and fractination using ethyl acetate solvent. Eluent used in isolation were n-hexane:ethyl acetate (8:2). The results of elucidation structure by using spectroscopy methods (GC-MS, NMR, and FTIR) was obtained 5-Hidroxy-2-(4-methoxy-phenyl)-8,8-dymethyl-8H-pyrano[2,3-f] chromen-4-one. This compound has an antibacterial and antioxidant activities.

Keywords


Ficus variegata Blume; flavonoid; antibacterial activities; antioxidant activities

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DOI: https://doi.org/10.22146/ijc.23947

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