Synthesis of Gold Nanoparticles Capped-Benzoic Acid Derivative Compounds (o-, m-, and p-Hydroxybenzoic Acid)

Agustina Sus Andreani(1*), Eko Sri Kunarti(2), Sri Juari Santosa(3)

(1) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara Yogyakarta 55281, Indonesia
(2) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara Yogyakarta 55281, Indonesia
(3) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara Yogyakarta 55281, Indonesia
(*) Corresponding Author


The effect of a hydroxyl functional group of the benzoic acid derivative compound, i.e. o-hydroxybenzoic acid, m-hydroxybenzoic acid, and p-hydroxybenzoic acid on the synthesis of AuNPs has been studied. It was revealed that the pH, heating time, the concentration of capping agent and the concentration of Au3+ affected the formation of AuNPs. We discovered that o-hydroxybenzoic acid possessed the highest stability, yet it needed the highest concentration of Au3+ and faster reaction time than p-hydroxybenzoic acid and slower than m-hydroxybenzoic acid. The stability was verified by means of UV-Vis spectrophotometer, XRD, TEM, Particle Size Analyzer (PSA), and Zeta Potential with an aging time of more than 5 months. We concluded that o-hydroxybenzoic acid acquired the most effective redox reaction instead of m-hydroxybenzoic acid and p-hydroxybenzoic acid, resulted in the smaller sized and unaggregated AuNPs. We also confirmed that the hydroxyl group of o-hydroxybenzoic acid, m-hydroxybenzoic acid and p-hydroxybenzoic acid is the functional group responsible for the reduction of Au3+ to Au0.


AuNPs; o-hydroxybenzoic acid; m-hydroxybenzoic acid; p-hydroxybenzoic acid

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[1] Shellaiah, M., Simon, T., Sun, K.W., and Ko, F.H., 2016, Simple bare gold nanoparticles for rapid colorimetric detection of Cr3+ ions in aqueous medium with real sample applications, Sens. Actuators, B, 226, 44–51.

[2] Li, J., Wang, X., Huo, D., Hou, C., Fa, H., Yang, M., and Zhang, L., 2017, Colorimetric measurement of Fe3+ using a functional paper-based sensor based on catalytic oxidation of gold nanoparticles, Sens. Actuators, B, 242, 1265–1271.

[3] Shrivas, K., Shankar, R., and Dewangan, K., 2015, Gold nanoparticles as a localized surface plasmon resonance based chemical sensor for on-site colorimetric detection of arsenic in water samples, Sens. Actuators, B, 220, 1376–1383.

[4] Turkevich, J., Stevenson, P.C., and Hillier, J., 1951, A study of the nucleation and growth process in the synthesis of colloidal gold, Discuss. Faraday Soc., 11, 55–75.

[5] Walekar, L.S., Pawar, S.P., Gore, A.H., Suryawanshi, V.D., Undare, S.S., Anbhule, P.V., Patil, S.R., and Kolekar, G.B., 2016, Surfactant stabilized AgNPs as a colorimetric probe for simple and selective detection of hypochlorite anion (ClO) in aqueous solution: Environmental sample analysis, Colloids Surf., A, 491, 78–85.

[6] Bialik-Wąs, K., Tyliszczak, B., Sobczak-Kupiec, A., Malina, D., and Piątkowski, M., 2012, The effect of dispersant concentration on properties of bioceramic particles, Dig. J. Nanomater. Biostruct., 7 (1), 361–366.

[7] Zhao, P., Li, N., and Astruc, D., 2013, State of the art in gold nanoparticle synthesis, Coord. Chem. Rev., 257 (3-4), 638–665.

[8] Kimling, J., Maier, M., Okenve, B., Kotaidis, V., Ballot, H., and Plech, A., 2006, Turkevich method for gold nanoparticle synthesis, J. Phys. Chem. B, 110 (32), 15700–15707.

[9] Fitriyana, F., and Kurniawan, F., 2015, Polyaniline-invertase-gold nanoparticles modified gold electrode for sucrose detection, Indones. J. Chem., 15 (3), 226–233.

[10] Roto, R., Marcelina, M., Aprilita, N.H., Mudasir, M., Natsir, T.A., and Mellisani, B., 2017, Investigation on the effect of addition of Fe3+ ion into the colloidal AgNPs in PVA solution and understanding its reaction mechanism, Indones. J. Chem., 17 (3), 439–445.

[11] Indumathy, R., Sreeram, K.J., Sriranjani, M., Aby, C.P., and Nair, B.U., 2010, Bifunctional role of thiosalicylic acid in the synthesis of silver nanoparticles, Mater. Sci. Appl., 1 (5), 272–278.

[12] Gusrizal, G., Santosa, S.J., Kunarti, E.S., and Rusdiarso, B., 2016, Dual function of p-hydroxybenzoic acid as reducing and capping agent in rapid and simple formation of stable silver nanoparticles, Int. J. ChemTech Res., 9 (9), 472–482.

[13] Gusrizal, G., Santosa, S.J., Kunarti, E.S., and Rusdiarso, B., 2017, Synthesis of silver nanoparticles by reduction of silver ion with m-hydroxybenzoic acid, Asian J. Chem., 29 (7), 1417–1422.

[14] Krishnamurthy, S., and Yun, Y.S., 2013, Recovery of microbially synthesized gold nanoparticles using sodium citrate and detergents, Chem. Eng. J., 214, 253–261.

[15] Qin, Y., Ji, X., Jing, J., Liu, H., Wu, H., and Yang, W., 2010, Size control over spherical silver nanoparticles by ascorbic acid reduction, Colloids Surf., A, 372, 172–176.

[16] Priyadarshini, E., and Pradhan, N., 2017, Gold nanoparticles as efficient sensors in colorimetric detection of toxic metal ions: A review, Sens. Actuators, B, 238, 888–902.

[17] Liu, J., Lee, J.B., Kim, D.H., and Kim, Y., 2007, Preparation of high concentration of silver colloidal nanoparticles in layered laponite sol, Colloids Surf., A, 302 (1-3), 276–279.

[18] Kaviya, S., and Prasad, E., 2014, Sequential detection of Fe3+ and As3+ ions by naked eye through aggregation and dis-aggregation of biogenic gold nanoparticles, Anal. Method, 7 (1), 168–174.

[19] Litvin, V.A., and Minaev, B.F., 2014, The size-controllable, one-step synthesis and characterization of gold nanoparticles protected by synthetic humic substances, Mater. Chem. Phys., 144 (1-2), 168–178.

[20] Ghosh, S.K., Pal, A., Kundu, S., Nath, S., and Pal, T., 2004, Fluorescence quenching of 1-methylaminopyrene near gold nanoparticles: Size regime dependence of the small metallic particles, Chem. Phys. Lett., 395 (4-6), 366–372.

[21] Li, S., Li, Y., Cao, J., Zhu, J., Fan, L., and Li, X., 2014, Sulfur-doped graphene quantum dots as a novel fluorescent probe for highly selective and sensitive detection of Fe3+, Anal. Chem., 86 (20), 10201–10207.

[22] Sánchez-Cortés, S., and García-Ramos, J.V., 2000, Adsorption and chemical modification of phenols on a silver surface, J. Colloid Interface Sci., 231 (1), 98–106.

[23] Alvarez-Ros, M.C., Sánchez-Cortés, S., and García-Ramos, J.V., 2000, Vibrational study of the salicylate interaction with metallic ions and surfaces, Spectrochim. Acta, Part A, 56 (12), 2471–2477.


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