Unlocking the Nutraceutical Potential of Adlay (Coix lacryma-jobi L.) and Its Applications from Food to Pharmaceuticals
Abstract
The nutraceutical industry has experienced remarkable global growth, driven by increasing consumer interest in natural health products. Adlay (Coix lacryma-jobi L.), an underutilized cereal, exhibits significant potential as a nutraceutical due to its rich nutritional and bioactive profile, but its explorations remain limited. This review aims to explore the nutraceutical potential of adlay and its applications in food and pharmaceutical formulations. Adlay contains key functional components, including starch, fiber, coixan, arabinoxylans, and various bioactive compounds that offer promising health benefits. It has been studied for its diverse pharmacological activities, such as anti-cancer, anti-obesity, immunomodulatory, and other effects. Traditionally consumed as food, adlay has also been developed into functional food products to enhance nutritional value. In pharmaceutical formulations, adlay has been incorporated into advanced delivery systems, such as microemulsions, liposomes, and nanostructured-lipid carriers, exhibiting synergistic effects in combination with chemotherapeutic agents for cancer treatment. Furthermore, toxicological studies suggest that adlay is generally safe for consumption, reinforcing its potential for further development as a nutraceutical ingredient in both food and pharmaceutical applications.
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