Hubungan Kadar Awal D-Dimer Terhadap Mortalitas pada Pasien COVID-19 Di RSUP Dr. Sardjito

Adam Alqustar; Juni Kurniawaty; Yunita  Widyastuti

doi:10.22146/jka.v10i1.8325

Submitted

May 28, 2023

Published

May 28, 2023

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Abstract

In severe COVID-19 infection, the immune response can be exaggerated and
cause a systemic cytokine storm that triggers systemic inflammatory response
syndrome (SIRS). Excessive systemic inflammatory response can lead to systemic
endothelial injury (endotheliopathy) and a hypercoagulable state that increases
the risk of systemic macrothrombosis and microthrombosis. D-dimers are
released when plasmin, a fibrinolytic enzyme, breaks down fibrin and is a
reflection of the endovascular thrombosis process. Assessment of circulating Ddimer concentrations is a sensitive test for diagnosing thrombotic status
(including pulmonary embolism and DIC) and predicting mortality event in
patient contracted with COVID- 19

Keywords

COVID-19 D-dimer CoagulopathY Thrombosis Mortality

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How to Cite

Alqustar, A., Kurniawaty, J., & Widyastuti, Y. (2023). Hubungan Kadar Awal D-Dimer Terhadap Mortalitas pada Pasien COVID-19 Di RSUP Dr. Sardjito. Jurnal Komplikasi Anestesi, 10(1), 35-44. https://doi.org/10.22146/jka.v10i1.8325

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Hubungan Kadar Awal D-Dimer Terhadap Mortalitas pada Pasien COVID-19 Di RSUP Dr. Sardjito

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