Chitosan-Polyvinyl Alcohol Films Embedded Curcumin-Capped ZnO-CuO Nanoparticles: Synthesis, Characterization and Antibacterial Activity

Ahmad Fatoni; Nabila Wulandari; Hilma Hilma; Nurlisa Hidayati

doi:10.22146/ijc.114008

Chitosan-Polyvinyl Alcohol Films Embedded Curcumin-Capped ZnO-CuO Nanoparticles: Synthesis, Characterization and Antibacterial Activity

https://doi.org/10.22146/ijc.114008

Ahmad Fatoni^(1*), Nabila Wulandari⁽²⁾, Hilma Hilma⁽³⁾, Nurlisa Hidayati⁽⁴⁾

(1) Pharmacy Study Program, Bhakti Pertiwi High School of Pharmacy Science, Jl. Ariodillah III No. 22, Palembang 30128, Indonesia
(2) Pharmacy Study Program, Bhakti Pertiwi High School of Pharmacy Science, Jl. Ariodillah III No. 22, Palembang 30128, Indonesia
(3) Pharmacy Study Program, Bhakti Pertiwi High School of Pharmacy Science, Jl. Ariodillah III No. 22, Palembang 30128, Indonesia
(4) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sriwijaya, Jl. Palembang Prabumulih Km. 32, Ogan Ilir 30662, Indonesia
(*) Corresponding Author

Abstract

This study employs the green synthesis approach of the film chitosan-polyvinyl alcohol-curcumin-capped ZnO-CuO nanoparticles (Chi-PVA-cur-capped ZnO-CuO NPs). To create a multifunctional material, the biological and bimetallic agents work in concert to create the new chi-PVA-cur-capped ZnO-CuO NPs film. Curcuma longa ethanol extract was utilized to create cur-capped ZnO–CuO NPs. The casting approach was used to create this film. FTIR, XRD, SEM-EDS, and the agar diffusion method were used to examine the films for antibacterial activity. Cur-capped ZnO-CuO NPs had a particle size of 485.24 ± 5.66 nm. The swelling degree, moisture content, and thickness were all raised in all three films, but the water-soluble matter was decreased. FTIR results verified the existence of some functional groups: O–H, N–H, C–H, C=O, amide I, Zn–O, and Cu–O groups. The XRD analysis verified that all the films were amorphous. All that is present in the film is C, O, Cu, and Zn, and it has a rough form area in the SEM image. The film of type C showed a zone of inhibition in Escherichia coli at 20.69 ± 1.15 mm. These results imply that all-film has a great deal of promise as a strong antibacterial packaging material.

Keywords

PVA; curcumin; ZnO-CuO; Escherichia coli

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References

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DOI: https://doi.org/10.22146/ijc.114008