Synthesis, Characterization and Antioxidant of Azo Ligand, Cr(III), Mn(II), and Mo(VI) Complexes

Shrouq Masad Khdair Al-Dulaimi; Abbas Ali Salih Al-Hamdani

doi:10.22146/ijc.114337

Synthesis, Characterization and Antioxidant of Azo Ligand, Cr(III), Mn(II), and Mo(VI) Complexes

https://doi.org/10.22146/ijc.114337

Shrouq Masad Khdair Al-Dulaimi⁽¹⁾, Abbas Ali Salih Al-Hamdani^(2*)

(1) Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad 10071, Iraq
(2) Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad 10071, Iraq
(*) Corresponding Author

Abstract

This paper presents a novel azo dye prepared by reacting a diazonium salt derived from 4-methylbenzene-1,2-diamine with 3,5-dimethylphenol. This dye was used to synthesize a new series of mononuclear compounds with the formulas [Cr(L)Cl(H₂O)], [Mn(L)(H₂O)₂], and [MoO₂L]. Various measurements were performed on the prepared materials to determine the proposed formulations, including infrared, ultraviolet-visible, and mass spectrometry measurements, as well as thermogravimetric and elemental analysis. The conductivity, magnetic susceptibility, metal content, and chlorine content of the compounds were also evaluated. The complexes prepared from the dye were used to assess their ability to inhibit free radicals by measuring their antioxidant capacity using DPPH as the free radical and gallic acid as the standard, and determining the IC₅₀ value. The ability of the compounds to inhibit free radicals varied according to their IC₅₀ values and their comparison with ascorbic acid. The Mo complex gave the highest ability to inhibit free radicals compared to the rest of the compounds with the order as follows: Gallic acid > [MoO₂L] > LH₂ > [Cr(L)(H₂O)Cl] > [Mn(L)(H₂O)₂] These suggest that the synthesized metal–azo dye complexes, particularly the Mo complex, have promising potential as antioxidant agents and may be useful for future applications in pharmaceutical field.

Keywords

antioxidant; azo dyes; metal complexes; 4-methylbenzene-1; 2-diamine; thermal analysis

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DOI: https://doi.org/10.22146/ijc.114337