IMPRINTING ZEOLITE-MODIFIED GLASSY CARBON AS A VOLTAMMETRIC SENSOR FOR URIC ACID

https://doi.org/10.22146/ijc.21292

Miratul Khasanah(1*), Muji Harsini(2), Alfa Akustia Widati(3)

(1) Chemistry Department, Faculty of Sciences and Technology, Airlangga University Kampus C Unair, Mulyorejo Surabaya, 60115
(2) Chemistry Department, Faculty of Sciences and Technology, Airlangga University Kampus C Unair, Mulyorejo Surabaya, 60115
(3) Chemistry Department, Faculty of Sciences and Technology, Airlangga University Kampus C Unair, Mulyorejo Surabaya, 60115
(*) Corresponding Author

Abstract


Development of the uric acid sensor through coating of glassy carbon (GC) electrode with imprinting zeolite (IZ) was carried out. Zeolite was synthesized by mixing TEOS, TBOT, TPAOH, and water followed by hydrothermal process. Zeolite was molded together with uric acid to produce IZ. The deposition potential of IZ and uric acid to the GC surface was -0.6 V during 150 sec with addition of KNO3 0.02 M as supporting electrolyte. The method gives linearity of 0.9834 (concentration 5.6x10-9M - 2.8x10-8 M), precision 1.89 - 7.65%, sensitivity 0.33 µA/nM/cm2, limit of detection 5.9x10-9 M, and accuracy 96.26 ± 0.55% (n = 5). The developed sensor showed a high selectivity toward uric acid. The presence of ascorbic acid, creatine, and creatinine with an equal concentration with uric acid did not interfere on the uric acid analysis.

Keywords


sensor; uric acid; voltammetry; imprinting zeolite; glassy carbon

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References

[1] Chen, J.-C., Chung, H.-H., Hsu, C.-T., Tsai, D.-M., Kumar, A.S., and Zen, J.-M., 2005, Sens. Actuators, B, 110, 2, 364–369.

[2] Khasanah, M., Supriyanto, G., Handajani, U.S., Fitriana, M., and Asmaningrum, W., 2007, Analysis of Uric Acid in Urine and Serum with Voltammetry Stripping Analysis using Hanging Mercury Drop Electrode, Proceeding of the ICOWOBAS, Universitas Airlangga, Surabaya, 6-7th August 2007, 307–311.

[3] Khasanah, M., Supriyanto, G., Wafiroh, S., Kuncaka, A., Sugiharto, E., and Mudasir, 2010, Indo. J. Chem., 10, 3, 295–300.

[4] Khasanah, M., Supriyanto, G., Tambunan, F.N., Mudasir, Kuncaka, A., and Sugiharto, E., 2010, Molecularly Imprinted Polymethacrylic Acid Modified Glassy Carbon as a Voltammetric Sensor of Uric Acid Analysis, Proceeding of the 2nd ICCS, Universitas Gadjah Mada, Yogyakarta, 14-16th October 2010, 457–460.

[5] Eimer, G.A., Díaz, I., Sastre, E., Casuscelli, S.G., Crivello, M.E., Herrero, E.R., and Perez-Pariente, J., 2008, Appl. Catal. A, 343, 1-2, 77–86.

[6] Goriushkina, T.B., Kurç, B.A., Sacco, A.Jr., and Dzyadevych, S.V., 2010, Sens. Electron. Microsys. Technol., 1, 36-42.

[7] Treacy, M.M.J., Higgins, J.B., and von Balloms, R., 2001, Collection of Simulated XRD Powder Patterns for Zeolite, 4th ed., Elsevier, Amsterdam.

[8] Mondal, P., and Deka, R.Ch., 2007, Bull. Catal. Soc. India, 6, 151–159.

[9] Fang, Y.M., and Hu, H.Q., 2007, Catal. Commun., 8, 817–820.

[10] Drago, R.S., Dias, S.C., McGilvray, J.M., and Mateus, A.L.M.L., 1998, J. Phys. Chem., 102, 9, 1508–1514.

[11] Taverniers, I., De Loose, M., and Van Bockstaele, E., 2004, Trends Anal. Chem., 23, 8, 535–552.

[12] Workman, J.Jr., and Mark, H., 2006, Spectroscopy, 21, 9, 18–24.

[13] Khasanah, M., 2012, Development of Stripping Voltammetric Method for Uric Acid Analysis through Electrode Coating with Molecular Imprinting Polymer, Dissertation, FMIPA UGM, Yogyakarta, 69–70.

[14] Zare, H.R., Memarzadeh, F., Ardakani, M.M., Namazian, M., and Golabi, S.M., 2005, Electrochim. Acta, 50, 16-17, 3495–3502.

[15] Lin, X-Q., and Jin, G-P., 2005, Electrochim. Acta, 50, 16-17, 3210–216.

[16] Zare, H.R., Rajabzadeh, N., and Ardakani, M.M., 2006, Electroanal. Chem., 589, 1, 60–69.

[17] Ren, W., Luo, H.Q., and Li, N.B., 2006, Biosens. Bioelectron., 21, 7, 1086–1092.

[18] Lin, X., and Li, Y., 2006, Electrochim. Acta, 51, 26, 5794–5801.

[19] Wei, Y., Li, M., Jiao, S., Huang, Q, Wang, G., and Fang, B., 2006, Electrochim. Acta, 52, 3, 766–772.

[20] Babaei, A., Zendehdel, M., Khalilzadeh, B., and Taheri, A., 2008, Colloids Surf., B, 66, 2, 226–232.

[21] Chen, P-Y., Vittal, R., Nien, P-C., Liou, G-S., and Ho, K-C., 2010, Talanta, 80, 3, 1145–1151.

[22] Lakshmi, D., Prasad, B.B., and Sharma, P.S., 2006, Talanta, 70, 2, 272–280.

[23] Lakshmi, D., Sharma, P.S. and Prasad, B.B., 2007, Biosens. Bioelectron., 22, 12, 3302–3308.



DOI: https://doi.org/10.22146/ijc.21292

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