Synthesis, Characterization and Antimicrobial Activity of Complexes Metal Ions Ni(II), Zn(ΙΙ), Pd(II) and Pt(IV) with Polydentate 1,2,4-Triazole Ligand

Sarab Mahdi Al-Alzawi; Mahmoud Najim Al-Jibouri; Anaam Majeed Rasheed; Sinan Midhat Al-Bayati

doi:10.22146/ijc.76716

Synthesis, Characterization and Antimicrobial Activity of Complexes Metal Ions Ni(II), Zn(ΙΙ), Pd(II) and Pt(IV) with Polydentate 1,2,4-Triazole Ligand

https://doi.org/10.22146/ijc.76716

Sarab Mahdi Al-Alzawi⁽¹⁾, Mahmoud Najim Al-Jibouri^(2*), Anaam Majeed Rasheed⁽³⁾, Sinan Midhat Al-Bayati⁽⁴⁾

(1) Department of Chemistry, College of Science, Mustansiriyah University, Baghdad 10052, Iraq
(2) Department of Chemistry, College of Science, Mustansiriyah University, Baghdad 10052, Iraq
(3) Department of Chemistry, College of Science, Mustansiriyah University, Baghdad 10052, Iraq
(4) Department of Chemistry, College of Science, Mustansiriyah University, Baghdad 10052, Iraq
(*) Corresponding Author

Abstract

A new ligand of 1,2,4-triazole derivative was produced by cyclization of sodium dithiocarbamate derivative of ethyl 4-ethoxy-3-nitrobenzoate with carbon disulfide in an alkaline medium. The new ligand, entitled name: L: 4-amino-5-(3-ethoxy-5-nitrophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione, was fully characterized depending on HPLC-MS, FTIR, ¹H-NMR and ¹³C-NMR spectroscopies. In addition, the elemental microanalysis was carried out to confirm the skeletal structure of the ligand L. A library of complexes with Ni(II), Zn(II), Pd(II), and Pt(IV) metal ions was prepared by coordination with the ligand. These complexes were characterized by using FTIR, UV-Ѵis, ¹H-NMR, ¹³C-NMR, spectrophotometric techniques, elemental analysis C.H.N.S, and FAAS. The physicochemical properties of these complexes were determined at 25 °C, such as melting point, magnetic susceptibility and molar conductivity. The microbial study confirmed that the novel ligand and its complexes have the potential to be applied as antimicrobial agents.

Keywords

1,2,4-triazole ligands; platinum(IV); palladium(II) complexes of triazole; microbial activity

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DOI: https://doi.org/10.22146/ijc.76716