Synthesis of Printed Hollow Fiber Membranes Urea as a Membrane Candidate Hemodialysis

Muhammad Cholid Djunaidi; Denandha Putri Ayuningrum; Nesti Dwi Maharani; Khabibi Khabibi; Pardoyo Pardoyo; Yanuardi Raharjo; Heru Susanto; Abdullah Malik Islam Filardli

doi:10.22146/ijc.83068

Synthesis of Printed Hollow Fiber Membranes Urea as a Membrane Candidate Hemodialysis

https://doi.org/10.22146/ijc.83068

Muhammad Cholid Djunaidi^(1*), Denandha Putri Ayuningrum⁽²⁾, Nesti Dwi Maharani⁽³⁾, Khabibi Khabibi⁽⁴⁾, Pardoyo Pardoyo⁽⁵⁾, Yanuardi Raharjo⁽⁶⁾, Heru Susanto⁽⁷⁾, Abdullah Malik Islam Filardli⁽⁸⁾

(1) Department of Chemistry, Faculty of Science and Mathematics, Diponegoro University, Jl. Prof. Soedharto SH, Tembalang, Semarang 50275, Indonesia
(2) Department of Chemistry, Faculty of Science and Mathematics, Diponegoro University, Jl. Prof. Soedharto SH, Tembalang, Semarang 50275, Indonesia
(3) Department of Chemistry, Faculty of Science and Mathematics, Diponegoro University, Jl. Prof. Soedharto SH, Tembalang, Semarang 50275, Indonesia
(4) Department of Chemistry, Faculty of Science and Mathematics, Diponegoro University, Jl. Prof. Soedharto SH, Tembalang, Semarang 50275, Indonesia
(5) Department of Chemistry, Faculty of Science and Mathematics, Diponegoro University, Jl. Prof. Soedharto SH, Tembalang, Semarang 50275, Indonesia
(6) Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Campus C, Mulyorejo, Surabaya 60115, Indonesia
(7) Department of Chemical Engineering, Faculty of Engineering, Diponegoro University, Jl. Prof. Soedharto SH, Tembalang, Semarang 50275, Indonesia
(8) Department of Chemical Engineering, Faculty of Engineering, Diponegoro University, Jl. Prof. Soedharto SH, Tembalang, Semarang 50275, Indonesia
(*) Corresponding Author

Abstract

Chronic kidney failure is a disease that affects the world's population and an alternative solution is hemodialysis. Hemodialysis is the process of cleaning the blood from urea and creatinine through a semi-permeable membrane in the form of a hollow fiber membrane (HFM) with the following advantages: flexible and low energy requirements. The weaknesses of commercial hemodialysis membranes are that they are hydrophobic, chemical resistant, and low biocompatibility. This research uses a membrane of polysulfone combined with eugenol and polyethylene glycol (PEG) or polyethylene glycol diglycidyl ether (PEGDE). Eugenol has allyl, hydroxy, and methoxy groups which are derived from polyeugenol via allyl groups and from polyeugenol to polyeugenoxy acetic acid via hydroxyl groups. The resulting molecularly imprinted membrane (MIM) in the form of hollow fiber has better porosity, absorption, flux values and is highly selective in transport, with the order of selectivity, namely urea > creatinine > vitamin B₁₂.

Keywords

hollow fiber; polyeugenoxy acetate; hemodialysis; imprinted

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DOI: https://doi.org/10.22146/ijc.83068