Mean the levels of 25(OH) D in the II trimester of pregnant women at Sleman, Indonesia

Abstract

Objective: Pregnant women possess a high risk of suffering from a deficiency of vitamin D3. A deficiency of Vitamin D3 is associated with pregnancy-related complications, such as preterm birth, preeclampsia, gestational diabetes, and babies born small for gestational age. Furthermore, it creates a risk of infection and breathing problems when the baby is born, and affects the life of the child.

Methods: A descriptive study was done and consisted of participants who met the following criteria: 20 - 35 years of age, BMI between 18.5-24.9, had a record of their last day of menstruation (HPHT). Informed consent was also obtained and signed by all the participants. Women who had histories of preeclampsia and eclampsia, bleeding, premature rupture of membranes, gemelli pregnancy, abortion, and immature births, and mothers with comorbidities such as heart, lung, liver, intestinal, bone, kidney, thyroid, and immunology diseases were excluded from the study. Examination of 25 (OH) D was done using Enzyme-Linked Immuno Sorbant Assay (ELISA) method with 1.5 ml of the sample which had been centrifuged and had its serum extracted.

Results: The study began in July 2020 with a total of 80 pregnant women in their second trimester (TM II). The participants had an average height of 154.5 cm and body weight before pregnancy of 51.8 kg. The results obtained showed insufficient levels of 25 (OH) D levels in  72 (90%) participants and sufficient/normal levels in 8 (10%) participants.

Conclusion: Most pregnant women at Sleman Indonesia had insufficient levels of 25 (OH) D.