A Comparison of Palm Oil, Beef Tallow, and Corn Oil Effect on Serum Glucose and Lipid Profile in Rats Fed a High-Fat Diet
Zaki Utama(1), Andriati Ningrum(2), Yunika Mayangsari(3), Sri Raharjo(4*)
(1) Departement of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada, Indonesia
(2) Departement of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada, Indonesia
(3) Departement of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada, Indonesia
(4) Departement of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada, Indonesia
(*) Corresponding Author
Abstract
This research aimed to investigate the influence of three types of palm oil products (RBDPO (refined bleached deodorized palm oi), RPO (red palm oil), and PKO (palm kernel oil)), on serum glucose and lipid profile of Sprague Dawley rats fed with experimental diet containing 20% of oils, comparing these effects with those of with animal- base oil (beef tallow) including corn oil as a representative from vegetable oil. The diet with level of fat 20% given to two groups (with and without AOM (azoxymethane)) of male Sprague Dawley rats for 13 weeks. The results exhibit that corn oil caused the lowest value of serum glucose (p < 0.05) in both AOM and non-AOM groups. Compared to other groups, beef tallow diet significantly increased serum triglycerides, cholesterol, and LDL, followed by RPO/PKO, RBDPO, and corn oil, respectively (p < 0.05). Meanwhile, corn oil diet produced the highest level of serum HDL, followed by RBDPO, PKO/RPO, and beef tallow (p < 0.05).
Keywords
References
Absalome, M. A., Massara, C. C., Alexandre, A. A., Gervais, K., Chantal, G. G. A., Ferdinand, D., Rhedoor, A. J., Coulibaly, I., George, T. G., Brigitte, T., Marion, M., & Jean-Paul, C. (2020). Biochemical properties, nutritional values, health benefits and sustainability of palm oil. Biochimie, 178, 81–95. https://doi.org/10.1016/j.biochi.2020.09.019
Akande, A. O., Jolayemi, O. S., Adelugba, V. A., & Akande, S. T. (2020). Silkworm pupae (Bombyx mori) and locusts as alternative protein sources for high-energy biscuits. Journal of Asia-Pacific Entomology, 23(1), 234–241. https://doi.org/10.1016/j.aspen.2020.01.003
Al-Hayder, M. N., Al-Mayyahi, R. S., & Abdul-Razak, A. S. (2020). Effects of sunflower oils and beef tallow on serum parameters and liver histopathology in experimental rats. Obesity Medicine, 18(April), 100232. https://doi.org/10.1016/j.obmed.2020.100232
Amini, S. A., Ghatreh-Samani, K., Habibi-Kohi, A., & Jafari, L. (2017). Comparison of pure palm olein oil, hydrogenated oil-containing palm, and canola on serum lipids and lipid oxidation rate in rats fed with these oils. Archives of Iranian Medicine, 20(2), 96–100. https://doi.org/0172002/AIM.007
Barham D, Trinder P. (1972). An improved color reagent for the determination of blood glucose by the oxidase system. Analyst, 97:142–145.
Brantley, K. D., Riis, A. H., Erichsen, R., Thorlacius-Ussing, O., Møller, H. J., & Lash, T. L. (2020). The association of serum lipid levels with colorectal cancer recurrence. Cancer Epidemiology, 66(December 2019), 101725. https://doi.org/10.1016/j.canep.2020.101725
Carrillo, W., Carpio, C., Morales, D., Vilcacundo, E., Alvarez, M., Silva, M. (2017). Content of fatty acids in corn (Zea mays L.) oil from Ecuador. Asian J Pharm Clin Res., 10(8), 150–153. http://dx.doi.org/10.22159/ajpcr.2017.v10i8.18786
Conlon, M. A., Sambanthamurthi, R., Tan, Y. A., Sundram, K., Fairus, S., Abeywardena, M. Y. (2020). Consumption of an oil palm fruit extract promotes large bowel health in rats. Nutrients, 12(644) https://doi.org/10.3390/nu12030644
Deeg R, Ziegenhorn J. (1983). Kinetic enzymatic method for automated determination of total cholesterol in serum. Clin Chem., 29:1798–1802.
Dhanasekara, C. S., Nelson, A., Spradley, M., Wynn, A., Robohm-Leavitt, C., Shen, C. L., & Kahathuduwa, C. N. (2022). Effects of consumption of coconut oil or coconut on glycemic control and insulin sensitivity: A systematic review and meta-analysis of interventional trials. Nutrition, Metabolism and Cardiovascular Diseases, 32(1), 53–68. https://doi.org/10.1016/j.numecd.2021.09.014
Dian, N. L. H. M., Hamid, R. A., Kanagaratnam, S., Isa, W. R. A., Hassim, N. A. M., Ismail, N. H., Omar, Z., & Sahri, M. M. (2017). Palm oil and palm kernel oil: Versatile ingredients for food applications. Journal of Oil Palm Research, 29(4), 487–511. https://doi.org/10.21894/jopr.2017.00014
Dupont, J., White, P. J., Carpenter, M. P., Schaefer, E. J., Meydani, S. N., Elson, C. E., Woods, M., Gorbach, S. L. (1990). Food uses and health effects of corn oil. Journal of the American College of Nutrition, 9:5, 438-470, DOI: 10.1080/07315724.1990.10720403
Edem, D. O. (2002). Palm oil: Biochemical, physiological, nutritional, hematological, and toxicological aspects: A review. Plant Foods for Human Nutrition, 57(3–4), 319–341. https://doi.org/10.1023/A:1021828132707
Fang, Z., He, M., & Song, M. (2021). Serum lipid profiles and risk of colorectal cancer: a prospective cohort study in the UK Biobank. British Journal of Cancer, 124(3), 663–670. https://doi.org/10.1038/s41416-020-01143-6
Hasibuan, H. A. (2012). Kajian mutu dan karakteristik minyak sawit Indonesia serta produk fraksinasinya. Jurnal Standardisasi 14(1), 13–21.
Hasibuan, H. A., Warnoto, Magrindin, Lubis, A. (2021). Produksi minyak sawit merah kapasitas 100kg/batch dan produk diversifikasinya berupa shortening dan margarin kapasitas 50 kg/batch. Warta PPKS, 26(1), 20–29.
Hwang, J. (2009). Diets with corn oil and/or low protein increase acute acetaminophen hepatotoxicity compared to diets with beef tallow in a rat model. Nutr Res Prac, 3(2), 95–101. https://doi.org/10.4162/nrp.2009.3.2.95
Jucáa, M. J., Bandeiraa, B. C., Carvalhoa, D. S., & Leal, A. T. (2014). Comparative study of 1,2-dimethylhydrazine and azoxymethane on the induction of colorectal cancer in rats Mario. Journal of Coloproctology, 34(3), 167–173. http://dx.doi.org/10.1016/j.jcol.2014.06.003
Jurgoński, A., Juśkiewicz, J., & Zduńczyk, Z. (2014). A high-fat diet differentially affects the gut metabolism and blood lipids of rats depending on the type of dietary fat and carbohydrate. Nutrients, 6(2), 616–626. https://doi.org/10.3390/nu6020616
Kadandale, S., Marten, R., & Smith, R. (2019). The palm oil industry and noncommunicable diseases. Bulletin of the World Health Organization, 97(2), 118–128. https://doi.org/10.2471/BLT.18.220434
Langlois MR, Blaton VH. (2006). Historical milestones in measurement of HDLcholesterol: Impact on clinical and laboratory practice. Clin Chimica Acta., 369:168–178.
Loganathan, R., Subramaniam, K. M., Radhakrishnan, A. K., Choo, Y. M., & Teng, K. T. (2017). Health-promoting effects of red palm oil: Evidence from animal and human studies. Nutrition Reviews, 75(2), 98–113. https://doi.org/10.1093/nutrit/nuw054
Mancini, A., Imperlini, E., Nigro, E., Montagnese, C., Daniele, A., Orrù, S., & Buono, P. (2015). Biological and nutritional properties of palm oil and palmitic acid: Effects on health. Molecules, 20(9), 17339–17361. https://doi.org/10.3390/molecules200917339
Miida T, Nishimura K, Okamura T, Hirayama S, Ohmura H. et al. (2014). Validation of homogeneous assays for HDL-cholesterol using fresh samples from healthy and diseased subjects. Atherosclerosis, 233(1):253–259.
N’guessan, B. B., Twumasi-Ankrah, J. S., Amponsah, S. K., Adams, I., Poakwah, A. K. K., Brown, C., Adinortey, M. B., Sarkodie, J. A., Adi-Dako, O., Asiedu-Gyekye, I. J., & Appiah-Opong, R. (2022). Effect of Metaswitch® dietary supplement on anthropometric parameters, serum lipids, glucose level, oxidative stress and in vivo antioxidant properties in high fat diet-induced overweight Sprague Dawley rats. Biomedicine and Pharmacotherapy, 149(March), 112892. https://doi.org/10.1016/j.biopha.2022.112892
Nagendran, B., Unnithan, U. R., Choo, Y. M., & Sundram, K. (2000). Characteristics of red palm oil, a carotene- and vitamin E-rich refined oil for food uses. Food and Nutrition Bulletin, 21(2), 189–194. https://doi.org/10.1177/156482650002100213
Nauck M, Warnwick GR, Rifai N. (2002). Methods for measurement of LDL-cholesterol: a critical assessment of direct measurement by homogeneous assays versus calculation. Clin Chem., 48:236–254.
Nie, Y., & Luo, F. (2021). Dietary Fiber: An Opportunity for a Global Control of Hyperlipidemia. Oxidative Medicine and Cellular Longevity, 2021. https://doi.org/10.1155/2021/5542342
Ockerman, H. W., Basu, L. (2014). Inedible, in Encyclopedia of Meat Sciences 2nd ed. vol. 1. Elsevier, London, UK.
Pavlisova, J., Bardova, K., Stankova, B., Tvrzicka, E., Kopecky, J., & Rossmeisl, M. (2016). Biochimie Corn oil versus lard : Metabolic effects of omega-3 fatty acids in mice fed obesogenic diets with different fatty acid composition. Biochimie, 124, 150–162. https://doi.org/10.1016/j.biochi.2015.07.001
Sarkar, D., Christopher, A., Shetty, K. (2022). Phenolic bioactives from plant-based foods for glycemic control. Front Endocrinol, 12:727503. https://doi.org/10.3389/fendo.2021.727503
Si, H., Zhang, L., Liu, S., Leroith, T., & Virgous, C. (2014). High corn oil dietary intake improves health and longevity of aging mice. EXG, 58, 244–249. https://doi.org/10.1016/j.exger.2014.09.001
Sujadi, Hasibuan, H. A., Rahmadi, H. Y., Purba, A. R. (2016). Composition of fatty acid and iod number from nine oil palm DxP commercial planting material in IOPRI. J Pen Kelapa Sawit 24(1), 1–12.
Syarifah-Noratiqah, S. B., Fairus, S., Zulfarina, M. S., Nasrullah, Z., Qodriyah, H. M. S., & Naina-Mohamed, I. (2020). The Effects of Palm Oil on Plasma and Serum Lipid Parameters: A Systematic Review on Animal Intervention Studies. Frontiers in Veterinary Science, 7(July). https://doi.org/10.3389/fvets.2020.00303
Szulczewska-Remi, A., Nogala-Kałucka, M., & Nowak, K. W. (2019). Study on the influence of palm oil on blood and liver biochemical parameters, beta-carotene and tocochromanols content as well as antioxidant activity in rats. Journal of Food Biochemistry, 43(2), 1–12. https://doi.org/10.1111/jfbc.12707
Tian, Y., Wang, K., Li, J., Wang, J., Wang, Z., Fan, Y., Ye, Y., Ji, G., & Li, Y. (2015). The association between serum lipids and colorectal neoplasm: A systemic review and meta-analysis. Public Health Nutrition, 18(18), 3355–3370. https://doi.org/10.1017/S1368980015000646
Urugo, M. M., Teka, T. A., Teshome, P. G., Tringo, T. T. (2021). Palm oil processing and controversies over its health effect: overview of positive and negative consequences. J Oleo Sci. 70(12), 1693–1706. https://doi.org/10.5650/jos.ess21160
Wang, F., Zhao, D., Yang, Y., & Lishi, Z. (2019). Effect of Palm Oil Consumption on Plasma Lipid Concentrations Related to Cardiovascular Disease: A Systematic Review and Meta-Analysis. Asia Pacific Journal of Clinical Nutrition, 28(3), 495–506. https://doi.org/10.6133/apjcn.201909_28(3).0009
Yao, X., & Tian, Z. (2015). Dyslipidemia and colorectal cancer risk: a meta-analysis of prospective studies. Cancer Causes and Control, 26(2), 257–268. https://doi.org/10.1007/s10552-014-0507-y
Zhang, X., Zhao, X. W., Liu, D. B., Han, C. Z., Du, L. L., Jing, J. X., & Wang, Y. (2014). Lipid levels in serum and cancerous tissues of colorectal cancer patients. World Journal of Gastroenterology, 20(26), 8646–8652. https://doi.org/10.3748/wjg.v20.i26.8646
Zulkiply, S. H., Balasubramaniam, V., Bakar, N. A. A., Rashed, A. A., & Ismail, S. R. (2019). Effects of palm oil consumption on biomarkers of glucose metabolism: A systematic review. PLoS ONE, 14(8), 1–14. https://doi.org/10.1371/journal.pone.0220877
DOI: https://doi.org/10.22146/agritech.84359
Article Metrics
Abstract views : 2403 | views : 694 | views : 804Refbacks
- There are currently no refbacks.
Copyright (c) 2024 Andriati Ningrum, Zaki Utama, Sri Raharjo, Agnes Murdiati
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
agriTECH has been Indexed by:
agriTECH (print ISSN 0216-0455; online ISSN 2527-3825) is published by Faculty of Agricultural Technology, Universitas Gadjah Mada in colaboration with Indonesian Association of Food Technologies.